4.8 Editorial Material

Mutations matter even if proteins stay the same

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NATURE
卷 606, 期 7915, 页码 -

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NATURE PORTFOLIO
DOI: 10.1038/d41586-022-01091-6

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Systematic editing of yeast genes to produce mutations reveals that the fitness of yeast is similarly affected by the mutations, regardless of whether the protein sequences encoded by the mutated genes change.
Systematic editing of yeast genes to generate thousands of mutations indicates that, overall, the mutations have similar effects on yeast fitness regardless of whether they change the protein sequences encoded by the mutated genes.

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