A new flavonoid glycoside from Toxicodendron vernicifluum (Stokes) FA Barkley

Toxicodendron vernicifluum (Stokes) F.A. Barkley, also called 'Qishu', is a shrub belonging to the Anacardiaceae family and producing lacquer. In this work, a new flavonoid glycoside (1), was isolated from the heartwood of T. vernicifluum, together with four known compounds (2-5). The structure of the new compound was determined as 4 ',7-dihydroxy-3 '-methoxy-3-O-beta-D-glucopyranosyl-flavonoid (1), on the basis of acidic hydrolysis, and spectroscopic analyses. Compound 1 showed significantly cytotoxic against A549 cell lines with the values of IC50 at 1.5 mu M.

Automated summary

In this study, a new flavonoid glycoside was isolated from the heartwood of Toxicodendron vernicifluum, together with four known compounds. The new compound showed significant cytotoxicity against A549 cell lines.