Electrochemical Immunoassay for Tumor Marker CA19-9 Detection Based on Self-Assembled Monolayer

Article Chemistry, Analytical

Morphologically Flex Sm-MOF Based Electrochemical Immunosensor for Ultrasensitive Detection of a Colon Cancer Biomarker

Sudip Biswas et al.

Summary: Rare earth metal-based MOFs were synthesized and used to fabricate label-free immunosensors for detection of carcinoembryonic antigen, demonstrating their potential in medical diagnosis.

ANALYTICAL CHEMISTRY (2022)

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Review Biochemistry & Molecular Biology

Electrochemical Signal Substance for Multiplexed Immunosensing Interface Construction: A Mini Review

Jiejie Feng et al.

Summary: This review summarizes the recent state-of-art development in the design of electrochemical immunosensing interface for simultaneous detection of multiple tumor markers, providing a comprehensive summary of signal substance selection.

MOLECULES (2022)

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Article Food Science & Technology

Current status of electrochemical detection of sunset yellow based on bibliometrics

Yuhong Zheng et al.

Summary: This study used bibliometrics to analyze the electrochemical detection of sunset yellow, including analyzing the countries, institutions, and years of publication, research directions, and hotspots, and ultimately summarized the development history and prospects of this topic.

FOOD AND CHEMICAL TOXICOLOGY (2022)

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Article Electrochemistry

A label-free Electrochemical Immunosensor Based on Polythionine-nanogold Nanocomposite for Detection of Trypsin Using screen-printed Electrode

Jianxiong Hu et al.

Summary: In this study, a label-free electrochemical immunosensor was developed to accurately detect trypsin in serum, which shows great potential for the diagnosis and monitoring of pancreatic diseases.

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE (2022)

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Review Chemistry, Analytical

Evaluation of Antioxidants Using Electrochemical Sensors: A Bibliometric Analysis

Yuhong Zheng et al.

Summary: This review summarizes the evaluation of antioxidants using electrochemical sensors by bibliometrics. The research priorities at different stages were discussed and perspectives for the future development of this topic were proposed.

SENSORS (2022)

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Article Chemistry, Analytical

A label-free electrochemical immunosensor for CA125 detection based on CMK-3(Au/Fc@MgAl-LDH)n multilayer nanocomposites modification

Mengdie Wu et al.

Summary: In this study, a label-free electrochemical immunosensor was constructed for the detection of cancer antigen 125 (CA125). This immunosensor used a multiple-enlargement means of layer-by-layer (LBL) assembly, incorporating ordered mesoporous carbon (CMK-3), gold nanoparticles (Au NPs), and MgAl layered double hydroxides containing ferrocenecarboxylic acid (Fc@MgAl-LDH). The LBL assembly approach greatly amplified the signal of the immunosensor and improved the immobilization of biomolecules.

TALANTA (2022)

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Review Chemistry, Analytical

Advances in Electrochemical Techniques for the Detection and Analysis of Genetically Modified Organisms: An Analysis Based on Bibliometrics

Yuhong Zheng et al.

Summary: This article interprets the application of electrochemical technology in the analysis and detection of transgenic products through bibliometrics. A total of 83 research articles spanning 2001 to 2021 were analyzed. The different stages in the development history of the subject and the contributions of countries and institutions to the topic were described. Different research directions on this topic were discussed through keyword co-occurrence analysis. The use of nanomaterials with excellent electrical conductivity allows for more sensitive detection of GM crops by electrochemical sensors. Furthermore, the most popular reports on the topic were interpreted using co-citation analysis. The future development of this topic was predicted based on the analysis results.

CHEMOSENSORS (2022)

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Article Environmental Sciences

Relationship between graphene and pedosphere: A scientometric analysis

Meiqing Jin et al.

Summary: This review summarizes the relationship between graphene and soils, including its applications in soil remediation, soil sensing, and effects on plant growth. Research findings suggest that graphene can alter soil physicochemical properties and microbial communities to some extent, but its impact on soil health is minimal.

CHEMOSPHERE (2022)

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Article Chemistry, Analytical

Ratiometric electrochemical immunosensor triggered by an advanced oxidation process for the ultrasensitive detection of carcinoembryonic antigen

Xiaochen Liao et al.

Summary: The novel ratiometric electrochemical immunosensor developed in this work offers ultrasensitive detection of carcinoembryonic antigen (CEA) by utilizing dual signals which enhance sensitivity and repeatability, showing promising applications in bioanalysis and disease diagnosis.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

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Article Nanoscience & Nanotechnology

Label-Free Electrochemical Immunosensor for Ultrasensitive Detection of Carbohydrate Antigen 125 Based on Antibody-Immobilized Biocompatible MOF-808/CNT

Sudip Biswas et al.

Summary: A high-performance nanocomposite of Zr-trimesic acid MOF (MOF-808) with carbon nanotube (CNT) was synthesized through in situ formation on activated CNT, showing excellent electrochemical properties and selectivity for ultra-low-level ovarian cancer biomarker detection.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Chemistry, Analytical

Detection of a novel glycodelin biomarker using electrochemical immunosensor for endometriosis

Thangapandi Kalyani et al.

Summary: Endometriosis is a major issue affecting women worldwide, and the use of an immunosensor to detect the GLY biomarker presents a new possibility for diagnosis, offering a sensitive and accurate alternative method.

ANALYTICA CHIMICA ACTA (2021)

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Review Electrochemistry

Fenton and Fenton-like catalysts for electrochemical immunoassay: A mini review

Jiejie Feng et al.

Summary: With the rapid development of electrochemical immunoassay, various catalysts are being used to improve the sensitivity of electrochemical immunosensors. Among these catalysts, Fenton and Fenton-like reactions are widely used due to their fast, mild, cost-effective, and environmentally friendly characteristics.

ELECTROCHEMISTRY COMMUNICATIONS (2021)

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Article Chemistry, Analytical

Carbohydrate antigen 19-9 electrochemical immunosensor based on 1D-MoS2 nanorods/LiNb3O8 and polyoxometalate-incorporated gold nanoparticles

Mehmet Lutfi Yola et al.

Summary: The study focuses on the development of an electrochemical immunosensor for CA 19-9 detection using 1D-MoS2 NRs/LNO and AuNPs@POM. The immunosensor shows high selectivity, stability, and reusability, providing a novel opportunity for clinical immunoassays.

MICROCHEMICAL JOURNAL (2021)

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Article Biophysics

Spatially-resolved dual-potential sandwich electrochemiluminescence immunosensor for the simultaneous determination of carbohydrate antigen 19-9 and carbohydrate antigen 24-2

Guichun Mo et al.

Summary: A new ECL immunosensor based on spatially-resolved dual-potential technology was developed for simultaneous detection of CA 19-9 and CA 242, showing high selectivity and stability in real sample analysis.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Chemistry, Analytical

Label-free electrochemical-immunoassay of cancer biomarkers: Recent progress and challenges in the efficient diagnosis of cancer employing electroanalysis and based on point of care (POC)

Soodabeh Hassanpour et al.

Summary: Early detection and accurate diagnosis of cancer are crucial for successful treatment, and immunosensors show promising potential in this field.

MICROCHEMICAL JOURNAL (2021)

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Review Chemistry, Analytical

Recent Progress in Electrochemical Immunosensors

JeeYoung Kim et al.

Summary: This paper reviews the recent progress in electrochemical immunosensors, focusing on the immobilization methods using antibodies for voltammetric, amperometric, impedimetric, and electrochemiluminescent immunosensors. The use of antibodies as molecular recognition molecules and the introduction of electrochemistry for quantitative signals are highlighted in the detection of biomarkers.

BIOSENSORS-BASEL (2021)

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Article Chemistry, Analytical

Ferric hydroxide nanocage triggered Fenton-like reaction to improve amperometric immunosensor

Xuanze Meng et al.

Summary: A new immunoprobe based on Fe(OH)3-NC was designed for constructing an amperometric immunosensor to detect tumor markers. The analytical performance of the immunosensor was remarkably enhanced by synthesizing Fe(OH)3-NC, immobilizing antibodies, and triggering a Fenton-like reaction.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Article Chemistry, Multidisciplinary

Construction of a Label-Free Electrochemical Immunosensor Based on Zn-Co-S/Graphene Nanocomposites for Carbohydrate Antigen 19-9 Detection

Chia-Wei Su et al.

Summary: Zn-Co-S@G nanocomposites were synthesized through a one-step hydrothermal method and showed promising performance in constructing an electrochemical immunosensor for CA19-9 detection. The strong interaction between Zn-Co-S and graphene facilitated the exposure of numerous electroactive sites, resulting in improved amplified electrochemical signals and a good linear relationship for detecting CA19-9.

NANOMATERIALS (2021)

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Article Chemistry, Analytical

Electrochemical immunosensor for detection of CA 15-3 biomarker in point-of-care

Tania S. C. R. Rebelo et al.

Summary: This work presents the development of a simple and rapid electrochemical immunosensor for the determination of the breast cancer biomarker CA 15-3. By using disposable gold screen-printed electrodes and covalently binding CA 15-3 antibody to the electrode surface, the sensor achieved sensitive detection at clinically relevant levels. Selectivity studies also demonstrated the high specificity of the antibody for CA 15-3 antigen, with successful application in quantifying CA 15-3 in artificial serum samples.

SENSING AND BIO-SENSING RESEARCH (2021)

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Article Chemistry, Multidisciplinary