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Potential Role of Quercetin in Polycystic Ovary Syndrome and Its Complications: A Review

期刊

MOLECULES
卷 27, 期 14, 页码 -

出版社

MDPI
DOI: 10.3390/molecules27144476

关键词

quercetin; antioxidant; polycystic ovary syndrome; mechanism

资金

  1. National Natural Science Foundation of China [81674011]
  2. China Academy of Chinese Medical Sciences [C120221A02404]

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Polycystic ovary syndrome is a common disease that seriously affects women's physical and mental health. Quercetin can intervene in the pathologic process of PCOS from multiple aspects, making it significant in the treatment of PCOS.
Polycystic ovary syndrome (PCOS) is a common multisystem disease with reproductive, metabolic and psychological abnormalities. It is characterized by a high prevalence rate in women of childbearing age and highly heterogeneous clinical manifestations, which seriously harm women's physical and mental health. Quercetin (QUR) is a natural compound of flavonoids found in a variety of foods and medicinal plants. It can intervene with the pathologic process of PCOS from multiple targets and channels and has few adverse reactions. It is mentioned in this review that QUR can improve ovulation disorder, relieve Insulin resistance (IR), reduce androgen, regulate lipid metabolism, regulate gut microbiota and improve vascular endothelial function, which is of great significance in the treatment of PCOS.

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