4.8 Article

Relevance of interactions between dopamine and glutamate neurotransmission in schizophrenia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Editorial Material Neurosciences

Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3

Neha Upmanyu et al.

Summary: Vesicular transporters determine the type of neurotransmitter stored and released by synaptic vesicles. Most vesicles contain only one type of transporter, while a small percentage have dual transporters. The colocalization of transporters influences the content and release of vesicles.

NEURON (2022)

Article Psychiatry

Machine Learning algorithm unveils glutamatergic alterations in the post-mortem schizophrenia brain

Arianna De Rosa et al.

Summary: This study investigates the role of glutamate signaling in schizophrenia by analyzing the levels of neuroactive amino acids and related molecules in the brains of schizophrenia patients and normal controls. The results reveal that variations in neuroactive amino acid levels and glutamate-related synaptic elements significantly affect the presence of schizophrenia. Furthermore, machine learning analysis identifies distinct clusters of molecules that can discriminate between schizophrenia patients and controls in different brain regions.

SCHIZOPHRENIA (2022)

Article Clinical Neurology

Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease

Thomas Steinkellner et al.

Summary: VGLUT2-expressing dopamine neurons exhibit resilience to degeneration and may be part of a neuroprotective response in Parkinson's disease.
Article Neurosciences

Heterogeneous expression of dopaminergic markers andVglut2in mouse mesodiencephalic dopaminergic nucleiA8-A13

Maxime Fougere et al.

Summary: Recent studies have identified three distinct expression patterns in dopamine neurons in mice along the rostrocaudal brain axis, providing insights into the homology of dopamine nuclei across vertebrate species.

JOURNAL OF COMPARATIVE NEUROLOGY (2021)

Article Behavioral Sciences

Modulation of mGlu5 improves sensorimotor gating deficits in rats neonatally treated with quinpirole through changes in dopamine D2 signaling

Russell W. Brown et al.

Summary: The study found that the positive allosteric modulator of mGlu5, CDPPB, can alleviate PPI deficits and striatal D2 signaling in the NQ model, without significant effects on locomotor activity.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2021)

Review Neurosciences

Disorganization of Oscillatory Activity in Animal Models of Schizophrenia

Lucinda J. Speers et al.

Summary: This article reviews the potential role of oscillatory circuits in schizophrenia, focusing on the hippocampus and frontal cortex. It discusses how a loss of oscillatory synchrony between brain regions may underlie some symptoms of the disorder. The disruption of phase precession in schizophrenia could contribute to cognitive symptoms such as deficits in memory and planning.

FRONTIERS IN NEURAL CIRCUITS (2021)

Article Neurosciences

VGLUT2 Is a Determinant of Dopamine Neuron Resilience in a Rotenone Model of Dopamine Neurodegeneration

Silas A. Buck et al.

Summary: The study found that DA neurons expressing VGLUT2 in the VTA/SNc exhibit higher resilience to rotenone-induced neurodegeneration, with an increase in VGLUT2 expression in response to rotenone. Dopaminergic terminals with VGLUT2 expression show greater protection throughout the striatum.

JOURNAL OF NEUROSCIENCE (2021)

Article Multidisciplinary Sciences

Striatal dopamine mediates hallucination-like perception in mice

K. Schmack et al.

Summary: Hallucination-like perception in mice was found to be correlated with elevated dopamine levels and could be induced by optogenetic stimulation, providing insights into the neural circuit mechanisms underlying hallucinations. These findings suggest potential for developing circuit-based treatments for psychotic disorders.

SCIENCE (2021)

Review Neurosciences

Dopamine Neurons That Cotransmit Glutamate, From Synapses to Circuits to Behavior

Daniel Eskenazi et al.

Summary: Dopamine neurons have the ability to cotransmit glutamate, playing significant roles in neuroprotection, behavioral responses, and neuropsychiatric disorders.

FRONTIERS IN NEURAL CIRCUITS (2021)

Article Multidisciplinary Sciences

Dopaminergic neuromodulation of prefrontal cortex the NMDA D-serine

Glenn Dallerac et al.

Summary: The study reveals the crucial role of D-serine in regulating glutamatergic transmission in the prefrontal cortex through D1 and D3 receptors, which are essential components in the dopamine-glutamate dialogue. In vivo microdialysis showed that D1 and D3 receptors modulate extracellular levels and activity of D-serine in the PFC via the cAMP/PKA signaling cascade. Furthermore, D-serine is necessary for the cognitive enhancement by D3 receptor blockade, as demonstrated in novel object recognition memory test.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Review Clinical Neurology

The role of dopamine D3receptors in the mechanism of action of cariprazine

Francesca Calabrese et al.

CNS SPECTRUMS (2020)

Article Psychiatry

Molecular alterations in the medial temporal lobe in schizophrenia

Anastasia M. Bobilev et al.

SCHIZOPHRENIA RESEARCH (2020)

Article Psychiatry

Dopamine and glutamate in schizophrenia: biology, symptoms and treatment

Robert A. McCutcheon et al.

WORLD PSYCHIATRY (2020)

Article Neurosciences

VGluT2 Expression in Dopamine Neurons Contributes to Postlesional Striatal Reinnervation

Willemieke M. Kouwenhoven et al.

JOURNAL OF NEUROSCIENCE (2020)

Review Pharmacology & Pharmacy

Hippocampal Hyperactivity as a Druggable Circuit-Level Origin of Aberrant Salience in Schizophrenia

Dennis Kaetzel et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Biochemistry & Molecular Biology

Memory and cognition in schizophrenia

J. Y. Guo et al.

MOLECULAR PSYCHIATRY (2019)

Review Psychiatry

D-Serine: Potential Therapeutic Agent and/or Biomarker in Schizophrenia and Depression?

Mary-Anne B. MacKay et al.

FRONTIERS IN PSYCHIATRY (2019)

Article Biochemistry & Molecular Biology

Dopamine-glutamate neuron projections to the nucleus accumbens medial shell and behavioral switching

Susana Mingote et al.

NEUROCHEMISTRY INTERNATIONAL (2019)

Review Neurosciences

Schizophrenia, Dopamine and the Striatum: From Biology to Symptoms

Robert A. McCutcheon et al.

TRENDS IN NEUROSCIENCES (2019)

Review Biochemistry & Molecular Biology

Serotonin and Glutamate Interactions in Preclinical Schizophrenia Models

Urjita H. Shah et al.

ACS CHEMICAL NEUROSCIENCE (2019)

Article Clinical Neurology

Human Striatal Response to Reward Anticipation Linked to Hippocampal Glutamate Levels

Matthijs G. Bossong et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2018)

Article Medicine, Research & Experimental

Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons

Thomas Steinkellner et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Article Neurosciences

Direct Glutamatergic Signaling From Midbrain Dopaminergic Neurons Onto Pyramidal Prefrontal Cortex Neurons

Jose Luis Perez-Lopez et al.

FRONTIERS IN NEURAL CIRCUITS (2018)

Review Psychiatry

Antipsychotics, Metabolic Adverse Effects, and Cognitive Function in Schizophrenia

Nicole E. MacKenzie et al.

FRONTIERS IN PSYCHIATRY (2018)

Article Multidisciplinary Sciences

Aversion or Salience Signaling by Ventral Tegmental Area Glutamate Neurons

David H. Root et al.

ISCIENCE (2018)

Article Neurosciences

Protein Markers of Neurotransmitter Synthesis and Release in Postmortem Schizophrenia Substantia Nigra

Kirsten E. Schoonover et al.

NEUROPSYCHOPHARMACOLOGY (2017)

Article Biochemistry & Molecular Biology

Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways

Lisha Shao et al.

HUMAN MOLECULAR GENETICS (2017)

Review Biochemistry & Molecular Biology

New Targets for Schizophrenia Treatment beyond the Dopamine Hypothesis

Albert C. Yang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Neurosciences

D3 Receptors Regulate Excitability in a Unique Class of Prefrontal Pyramidal Cells

Rebecca L. Clarkson et al.

JOURNAL OF NEUROSCIENCE (2017)

Review Neurosciences

Striatal dopamine neurotransmission: Regulation of release and uptake

David Sulzer et al.

BASAL GANGLIA (2016)

Review Neurosciences

Inhibitory and excitatory neuromodulation by hydrogen peroxide: translating energetics to information

Christian R. Lee et al.

JOURNAL OF PHYSIOLOGY-LONDON (2015)

Review Clinical Neurology

Glutamate and dopamine in schizophrenia: An update for the 21st century

Oliver Howes et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2015)

Article Neurosciences

Dopaminergic and glutamatergic microdomains in a subset of rodent mesoaccumbens axons

Shiliang Zhang et al.

NATURE NEUROSCIENCE (2015)

Article Neurosciences

Function and developmental origin of a mesocortical inhibitory circuit

Anna Kabanova et al.

NATURE NEUROSCIENCE (2015)

Review Physiology

NEURONAL REWARD AND DECISION SIGNALS: FROM THEORIES TO DATA

Wolfram Schultz

PHYSIOLOGICAL REVIEWS (2015)

Article Clinical Neurology

The glutamate hypothesis of schizophrenia: evidence from human brain tissue studies

Wei Hu et al.

YEAR IN NEUROLOGY AND PSYCHIATRY (2015)

Article Multidisciplinary Sciences

Synaptic dysregulation in a human iPS cell model of mental disorders

Zhexing Wen et al.

NATURE (2014)

Article Multidisciplinary Sciences

Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models

Sungkun Chun et al.

SCIENCE (2014)

Article Psychiatry

Schizophrenia Is a Cognitive Illness Time for a Change in Focus

Rene S. Kahn et al.

JAMA PSYCHIATRY (2013)

Review Physiology

Neurotransmitter Corelease: Mechanism and Physiological Role

Thomas S. Hnasko et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 74 (2012)

Article Biochemistry & Molecular Biology

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

Thomas Papouin et al.

Article Neurosciences

Glial D-Serine Gates NMDA Receptors at Excitatory Synapses in Prefrontal Cortex

Pascal Fossat et al.

CEREBRAL CORTEX (2012)

Review Pharmacology & Pharmacy

Genetic Data Supporting the NMDA Glutamate Receptor Hypothesis for Schizophrenia

Thomas L. Schwartz et al.

CURRENT PHARMACEUTICAL DESIGN (2012)

Article Pharmacology & Pharmacy

Glutamate neurocircuitry: theoretical underpinnings in schizophrenia

Thomas L. Schwartz et al.

FRONTIERS IN PHARMACOLOGY (2012)

Review Neurosciences

Inverted-U-Shaped Dopamine Actions on Human Working Memory and Cognitive Control

Roshan Cools et al.

BIOLOGICAL PSYCHIATRY (2011)

Letter Biochemistry & Molecular Biology

Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study

O. Howes et al.

MOLECULAR PSYCHIATRY (2011)

Article Multidisciplinary Sciences

Modelling schizophrenia using human induced pluripotent stem cells

Kristen J. Brennand et al.

NATURE (2011)

Review Neurosciences

From glutamate co-release to vesicular synergy: vesicular glutamate transporters

Salah El Mestikawy et al.

NATURE REVIEWS NEUROSCIENCE (2011)

Review Biochemistry & Molecular Biology

Targeting glutamate synapses in schizophrenia

Julie R. Field et al.

TRENDS IN MOLECULAR MEDICINE (2011)

Review Psychiatry

Roles of the Akt/GSK-3 and Wnt Signaling Pathways in Schizophrenia and Antipsychotic Drug Action

Zachary Freyberg et al.

AMERICAN JOURNAL OF PSYCHIATRY (2010)

Review Psychiatry

The Hippocampal Formation in Schizophrenia

Carol A. Tamminga et al.

AMERICAN JOURNAL OF PSYCHIATRY (2010)

Review Biochemistry & Molecular Biology

The neurobiology of D-amino acid oxidase and its involvement in schizophrenia

L. Verrall et al.

MOLECULAR PSYCHIATRY (2010)

Review Pharmacology & Pharmacy

Signaling pathways in schizophrenia: emerging targets and therapeutic strategies

Caline S. Karam et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2010)

Article Neurosciences

The Neuropsychopharmacology of Fronto-Executive Function: Monoaminergic Modulation

T.W. Robbins et al.

Annual Review of Neuroscience (2009)

Article Psychiatry

Elevated Striatal Dopamine Function Linked to Prodromal Signs of Schizophrenia

Oliver D. Howes et al.

ARCHIVES OF GENERAL PSYCHIATRY (2009)

Article Neurosciences

The Dual Dopamine-Glutamate Phenotype of Growing Mesencephalic Neurons Regresses in Mature Rat Brain

Noemie Berube-Carriere et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2009)

Review Behavioral Sciences

Prefrontal cortex-nucleus accumbens interaction:: In vivo modulation by dopamine and glutamate in the prefrontal cortex

Alberto Del Arco et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2008)

Review Clinical Neurology

The amphetamine-induced sensitized state as a model of schizophrenia

R. E. Featherstone et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2007)

Article Biochemistry & Molecular Biology

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

Sandeep T. Patil et al.

NATURE MEDICINE (2007)

Article Neurosciences

A genetic variant of the serine racemase gene is associated with schizophrenia

Yukitaka Morita et al.

BIOLOGICAL PSYCHIATRY (2007)

Article Neurosciences

Prefrontal cortical projections to the midbrain in primates: Evidence for a sparse connection

William Gordon Frankle et al.

NEUROPSYCHOPHARMACOLOGY (2006)

Review Neurosciences

The principal features and mechanisms of dopamine modulation in the prefrontal cortex

JK Seamans et al.

PROGRESS IN NEUROBIOLOGY (2004)

Article Clinical Neurology

Antipsychotic drugs, dopamine receptors, and schizophrenia

P Seeman

CLINICAL NEUROSCIENCE RESEARCH (2001)

Article Multidisciplinary Sciences

D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor

JP Mothet et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Biochemistry & Molecular Biology

Dale's principle and glutamate corelease from ventral midbrain dopamine neurons

D Sulzer et al.

AMINO ACIDS (2000)