期刊
MOLECULAR BIOLOGY REPORTS
卷 49, 期 11, 页码 10825-10847出版社
SPRINGER
DOI: 10.1007/s11033-022-07770-x
关键词
lncRNA; miRNA; circRNA; HNSCC; Cytokines; Chemokines
资金
- OPERA Grant from BITS Pilani-Hyderabad Campus
- CHDR Grant from BITS Pilani-Hyderabad Campus
- ICMR [2021-10878]
- DST Inspire fellowship [IF190343]
Head and neck squamous cell carcinoma (HNSCC) is a leading cause of cancer-related death worldwide, and recurrence poses a challenge. Cytokines play a crucial role in promoting HNSCC growth and anti-tumor immune response, while non-coding RNAs (ncRNAs) also play a key role in regulating cytokine function.
Head and neck squamous cell carcinoma (HNSCC) is a leading cause of cancer-related death worldwide. Despite aggressive treatment approaches, the recurrence of HNSCC remains a challenge. Cytokines play an essential role in HNSCC development and progression. They are not only involved in promoting cancer growth but may also be involved in an anti-tumor immune response. Non-coding RNAs (ncRNAs) have emerged as important transcriptional and post-transcriptional mediators of cytokine function in HNSCC. This review focuses on the complex regulatory network among regulatory ncRNAs and cytokines during HNSCC pathogenesis.
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