期刊
MOLECULAR BIOLOGY AND EVOLUTION
卷 39, 期 8, 页码 -出版社
OXFORD UNIV PRESS
DOI: 10.1093/molbev/msac166
关键词
multiple sequence alignment; suffix tree; center star strategy; common substring; substring selection
资金
- National Natural Science Foundation of China [62131004, 62001311, 61922020]
- Special Science Foundation of Yangtze Delta Region Institute (Quzhou) [2020D004]
- Research Foundation of Shenzhen Polytechnic [6021310016K, 6021330003K]
- China Postdoctoral Science Foundation [2021M700702]
HAlign is a cross-platform program for multiple sequence alignments based on the center star strategy. The major updates of HAlign 3 improved time efficiency and alignment quality, making it a specialized program for processing large numbers of similar DNA/RNA sequences.
HAlign is a cross-platform program that performs multiple sequence alignments based on the center star strategy. Here we present two major updates of HAlign 3, which helped improve the time efficiency and the alignment quality, and made HAlign 3 a specialized program to process ultra-large numbers of similar DNA/RNA sequences, such as closely related viral or prokaryotic genomes. HAlign 3 can be easily installed via the Anaconda and Java release package on macOS, Linux, Windows subsystem for Linux, and Windows systems, and the source code is available on GitHub (https://github.com/malabz/HAlign-3).
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