Phenylalanine biosensor based on a nanostructured fiberglass paper support and fluorescent output signal readable with a smartphone

Article Biophysics

Wearable wristband-based electrochemical sensor for the detection of phenylalanine in biofluids

Marc Parrilla et al.

Summary: Wearable wristband electrochemical sensor is developed for monitoring PHE levels in PKU patients, aiming to control the disease, simplify the sample processing process, and achieve the determination of PHE in saliva and blood serum.

BIOSENSORS & BIOELECTRONICS (2022)

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Article Chemistry, Analytical

A universal nanostructured bioanalytical platform for NAD+-dependent enzymes based on the fluorescent output reading with a smartphone

Yacob Melman et al.

Summary: A nanostructured surface was used as a platform to immobilize NAD(+)-dependent enzymes for fluorescent analysis of substrates. The signal was obtained by processing fluorescent images using a smartphone. This system has potential applications in various fields including biomedical, forensic, homeland security, and environmental monitoring.

TALANTA (2022)

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Article Biochemistry & Molecular Biology

Paper-based biosensor based on phenylalnine ammonia lyase hybrid nanoflowers for urinary phenylalanine measurement

Baoting Sun et al.

Summary: Phenylketonuria (PKU) is a genetic defect in phenylalanine metabolism. A novel paper-based biosensor for semi-quantitative detection of phenylalanine in urine samples was developed, showing good stability and reusability.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Chemistry, Analytical

Surface Plasmon Resonance Based on Molecularly Imprinted Polymeric Film for l-Phenylalanine Detection

Duygu Cimen et al.

Summary: The study designed a surface plasmon resonance sensor for detecting L-phenylalaine using molecular imprinting technology, achieving rapid, sensitive, and selective detection. Characterization and kinetic studies were conducted, revealing good detection limits and response time in various experiments.

BIOSENSORS-BASEL (2021)

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Article Chemistry, Analytical

Colorimetric biosensor for phenylalanine detection based on a paper using gold nanoparticles for phenylketonuria diagnosis

Pouria Jafari et al.

Summary: A colorimetric paper-based biosensor was developed for the sensitive and selective determination of phenylalanine, with the color change indicating the concentration of phenylalanine. The method is easy to operate, provides quick results, has a wide linear range, and can be used for screening PKU in newborns.

MICROCHEMICAL JOURNAL (2021)

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Article Food Science & Technology

Phenylalanine-responsive fluorescent biosensor based on graphene oxide-chitosan nanocomposites catalytic film for non-destructive fish freshness grading

Farah Faiqah Fazial et al.

Summary: An optical enzymatic phenylalanine biosensor has been developed for non-invasive evaluation of fish freshness by detecting biofluid from the fish body surface. The biosensor showed a fast response time and a low detection limit, making it a practical tool for assessing fish quality.

FOOD CONTROL (2021)

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Article Chemistry, Physical