4.5 Article

TLR2, TLR4, and NLRP3 mediated the balance between host immune-driven resistance and tolerance in Staphylococcus aureus-infected mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Critical Care Medicine

Vitamin C, Hydrocortisone, and the Combination Thereof Significantly Inhibited Two of Nine Inflammatory Markers Induced by Escherichia Coli But Not by Staphylococcus Aureus - When Incubated in Human Whole Blood

Pedro Miguel Coelho Medeiros et al.

Summary: The use of vitamin C combined with hydrocortisone to treat septic patients is controversial, and this study in an ex vivo human blood model suggests that the effect of this treatment on bacterial-induced inflammation is limited and consistent with clinical data.
Article Immunology

Fetal inflammation induces acute immune tolerance in the neonatal rat hippocampus

Garima Singh et al.

Summary: Research shows that prenatal LPS exposure-induced FIRS attenuates the hippocampal immune response to postnatal LPS in premature infants, without evidence of immune tolerance.

JOURNAL OF NEUROINFLAMMATION (2021)

Article Cell Biology

Itaconate confers tolerance to late NLRP3 inflammasome activation

Monika Bambouskova et al.

Summary: Itaconate, induced upon TLR stimulation, regulates NLRP3 inflammasome activation and synergizes with iNOS, establishing tolerance to NLRP3 inflammasome in inflammatory macrophages. Mechanistically, itaconate prevents full caspase-1 activation and gasdermin D processing, potentially leading to pyroptotic cell death and tissue damage if not controlled.

CELL REPORTS (2021)

Review Microbiology

Bacteria and Host Interplay in Staphylococcus aureus Septic Arthritis and Sepsis

Tao Jin et al.

Summary: Staphylococcus aureus infections pose a significant healthcare challenge, necessitating the development of new treatment options. Understanding the interaction between bacterial virulence factors and host immune response is crucial for determining disease outcomes. The timing and approach of treatment play a critical role in the effectiveness of therapies.

PATHOGENS (2021)

Article Multidisciplinary Sciences

Targeting Gα13-integrin interaction ameliorates systemic inflammation

Ni Cheng et al.

Summary: The study demonstrates that targeting integrin outside-in signaling in leukocytes and platelets can alleviate inflammation and clotting in septic mice, improving survival rates.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Orchestration of human macrophage NLRP3 inflammasome activation by Staphylococcus aureus extracellular vesicles

Xiaogang Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Microbiology

Staphylococcus aureus bloodstream infections: pathogenesis and regulatory mechanisms

Jakub M. Kwiecinski et al.

CURRENT OPINION IN MICROBIOLOGY (2020)

Article Multidisciplinary Sciences

Staphylococcus aureus targets the purine salvage pathway to kill phagocytes

Volker Winstel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Cell Biology

Emerging role of HMGB1 in lung diseases: friend or foe

Junying Ding et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2017)

Article Infectious Diseases

TLR4 genetic variation is associated with inflammatory responses in Gram-positive sepsis

N. Chantratita et al.

CLINICAL MICROBIOLOGY AND INFECTION (2017)

Article Cell Biology

Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling

Michael B. Murphy et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2015)

Review Physiology

NOD-LIKE RECEPTORS: VERSATILE CYTOSOLIC SENTINELS

Vinicius Motta et al.

PHYSIOLOGICAL REVIEWS (2015)

Review Microbiology

Immunomodulation and Disease Tolerance to Staphylococcus aureus

Zhigang Li et al.

PATHOGENS (2015)

Review Medicine, General & Internal

Clinical Management of Staphylococcus aureus Bacteremia A Review

Thomas L. Holland et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)

Review Immunology

Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy

Richard S. Hotchkiss et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Review Multidisciplinary Sciences

Disease Tolerance as a Defense Strategy

Ruslan Medzhitov et al.

SCIENCE (2012)

Review Immunology

Neutrophils in innate host defense against Staphylococcus aureus infections

Kevin M. Rigby et al.

SEMINARS IN IMMUNOPATHOLOGY (2012)

Review Immunology

Armed response: how dying cells influence T-cell functions

Thomas A. Ferguson et al.

IMMUNOLOGICAL REVIEWS (2011)

Article Agriculture, Dairy & Animal Science

Lipopolysaccharide and lipoteichoic acid induce different immune responses in the bovine mammary gland

O. Wellnitz et al.

JOURNAL OF DAIRY SCIENCE (2011)

Review Immunology

Immunity against Staphylococcus aureus cutaneous infections

Lloyd S. Miller et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Article Immunology

Toll-like Receptor 2 Ligand-Induced Protection against Bacterial Endophthalmitis

Ashok Kumar et al.

JOURNAL OF INFECTIOUS DISEASES (2010)

Review Microbiology

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

Trine H. Mogensen

CLINICAL MICROBIOLOGY REVIEWS (2009)

Review Immunology

Endotoxin tolerance: new mechanisms, molecules and clinical significance

Subhra K. Biswas et al.

TRENDS IN IMMUNOLOGY (2009)

Article Multidisciplinary Sciences

Gene-specific control of inflammation by TLR-induced chromatin modifications

Simmie L. Foster et al.

NATURE (2007)

Review Immunology

Cooperation of Toll-like receptor signals in innate immune defence

Giorgio Trinchieri et al.

NATURE REVIEWS IMMUNOLOGY (2007)

Review Immunology

HMGB1: guiding immunity from within

IE Dumitriu et al.

TRENDS IN IMMUNOLOGY (2005)

Review Immunology

Toll-like receptor signalling

S Akira et al.

NATURE REVIEWS IMMUNOLOGY (2004)