4.7 Article

Synergistic effects on itaconic acid production in engineered Aspergillus niger expressing the two distinct biosynthesis clusters from Aspergillus terreus and Ustilago maydis

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Summary: Itaconic acid is a versatile molecule with a wide range of applications, which can be produced through both chemical and biological routes. Although Aspergillus terreus is a prevalent microbial cell factory for itaconic acid production, high manufacturing costs remain a challenge. To enable wider applications, a low-cost production process and improved strain performance are essential.

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