期刊
JOURNAL OF SURGICAL ONCOLOGY
卷 126, 期 6, 页码 1058-1066出版社
WILEY
DOI: 10.1002/jso.26998
关键词
core needle biopsy; diagnostic imaging; fine-needle aspiration cytology; melanoma; surgical oncology
The diagnostic accuracy of ultrasound guided fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) in melanoma patients with suspected metastasis was investigated in this study. The results showed no significant differences in diagnostic accuracy between FNAC and CNB in different clinical scenarios. However, there were significantly fewer nondiagnostic biopsies when using CNB.
Background and Objective The aim of this study was to investigate the diagnostic accuracy of ultrasound guided fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) in different clinical scenarios for melanoma patients with lesions suspected of metastasis. Methods We included all patients at our department attending follow-up after surgery for cutaneous melanoma, who had undergone either FNAC or CNB between December 2016 and June 2019. Biopsy results were classified into one of four categories and verified with follow-up including imaging, re-biopsy or histology upon excision. The diagnostic accuracy of FNAC and CNB were calculated overall, and based on location of suspected metastasis, reason for suspicion and stage. Results We identified 232 biopsies in 164 patients; 109 FNACs and 123 CNBs. For FNAC, overall sensitivity was 83.3% and negative predictive value was 88.4%. For CNB, overall sensitivity was 92.4% and negative predictive value was 88.0%. There were significantly fewer nondiagnostic results using CNB compared to FNAC (chi(2)(1) = 6.7, p = 0.0095). Conclusions There were no significant differences between the diagnostic accuracy of FNAC and CNB in the different clinical scenarios. We found significantly fewer nondiagnostic biopsies when using CNB, although this may reflect the type of lesions selected for each approach.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据