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Daniela Castanotto et al.
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Nancy Standart et al.
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William T. Booth et al.
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Elad Elkayam et al.
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Ryan J. Golden et al.
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Judith Hauptmann et al.
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Huili Guo et al.
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Young Sik Lee et al.
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Derrick J. Gibbings et al.
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Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps
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CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs
Daniela Castanotto et al.
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David G. Hendrickson et al.
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Yan Zeng et al.
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Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs
Susana Gonzalez et al.
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Thomas Ohrt et al.
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In vitro reconstitution of the human RISC-loading complex
Ian J. MacRae et al.
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Sabine Ruedel et al.
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Markus Landthaler et al.
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Dual role for argonautes in MicroRNA processing and Posttranscriptional regulation of MicroRNA expression
Sven Diederichs et al.
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Julia Hoeck et al.
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MicroRNA silencing through RISC recruitment of eIF6
Thimmaiah P. Chendrimada et al.
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P-body formation is a consequence, not the cause, of RNA-mediated gene silencing
Ana Eulalio et al.
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RNA helicase A interacts with RISC in human cells and functions in RISC loading
G. Brett Robb et al.
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Patricia A. Maroney et al.
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Anthony K. L. Leung et al.
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MRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
Isabelle Behm-Ansmant et al.
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Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54
Chia-ying Chu et al.
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Relief of microRNA-mediated translational repression in human cells subjected to stress
Suvendra N. Bhattacharyya et al.
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Identification of novel argonaute-associated proteins
G Meister et al.
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A role for the P-body component GW182 in microRNA function
JD Liu et al.
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Disruption of GW bodies impairs mammalian RNA interference
A Jakymiw et al.
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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
RI Gregory et al.
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Inhibition of translational initiation by Let-7 microRNA in human cells
RS Pillai et al.
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Characterization of Dicer-deficient murine embryonic stem cells
EP Murchison et al.
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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
TP Chendrimada et al.
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JD Liu et al.
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GL Sen et al.
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MicroRNA-directed cleavage of HOXB8 mRNA
S Yekta et al.
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JD Liu et al.
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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
G Meister et al.
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RISC is a 5′ phosphomonoester-producing RNA endonuclease
J Martinez et al.
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Functional siRNAs and rniRNAs exhibit strand bias
A Khvorova et al.
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J Martinez et al.
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T Eystathioy et al.
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Z Mourelatos et al.
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ATP requirements and small interfering RNA structure in the RNA interference pathway
A Nykänen et al.
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G Hutvágner et al.
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SM Hammond et al.
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