Sodium Bicarbonate Locks May Be a Safe and Effective Alternative in Pediatric Intestinal Failure: A Pilot Study

Article Nutrition & Dietetics

Anticipated impact of recent ethanol lock shortage and price increase on practice among pediatric intestinal rehabilitation programs across the United States

Saurabh Talathi et al.

Summary: Most US providers use ethanol locks in children with intestinal failure, but many are experiencing or anticipating reduced access to these locks. Concerns have been raised that limited access to ethanol locks may lead to an increase in CLABSI rates in this vulnerable patient population. Further research is needed to explore alternative locking agents for CLABSI prevention.

JOURNAL OF PARENTERAL AND ENTERAL NUTRITION (2022)

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Article Nutrition & Dietetics

ASPEN definitions in pediatric intestinal failure

Biren P. Modi et al.

Summary: Pediatric intestinal failure is a rare disease that lacks consensus in key terms definition, but the ASPEN PIF Section has created evidence-based consensus definitions to address this issue.

JOURNAL OF PARENTERAL AND ENTERAL NUTRITION (2022)

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Article Nutrition & Dietetics

Reduction of Central Line-Associated Bloodstream Infections and Line Occlusions in Pediatric Intestinal Failure Patients Receiving Long-Term Parenteral Nutrition Using an Alternative Locking Solution, 4% Tetrasodium Ethylenediaminetetraacetic Acid

Jill Quirt et al.

Summary: This retrospective cohort study of 20 pediatric patients with intestinal failure (IF) found that 4% tetrasodium ethylenediaminetetraacetic acid (EDTA) solution was effective in reducing central line-associated bloodstream infections (CLABSIs) and line occlusions. Data showed no infections in the 12 months post-therapy and a significant decrease in occlusive episodes after starting EDTA therapy. These preliminary findings suggest the efficacy of 4% tetrasodium EDTA in reducing CLABSIs and catheter occlusions in pediatric patients with long-term central-access.

JOURNAL OF PARENTERAL AND ENTERAL NUTRITION (2021)

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Article Gastroenterology & Hepatology

Management of Central Venous Access in Children With Intestinal Failure: A Position Paper From the NASPGHAN Intestinal Rehabilitation Special Interest Group

Danielle Wendel et al.

Summary: Intestinal failure necessitates long-term central venous catheter care, but variations in care practices lead to significant changes in central venous access management. Recommendations for central line management have been proposed to reduce complications and mortality rates.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2021)

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Article Urology & Nephrology

A Randomized Controlled Trial of Comparative Efficacy between Sodium Bicarbonate and Heparin as A Locking Solution for Tunneled Central Venous Catheters Among Patients Requiring Maintenance Hemodialysis

Wannasit Wathanavasin et al.

Summary: The use of sodium bicarbonate locking solution for prevention of catheter-related thrombosis in prevalent hemodialysis patients with tunneled central venous catheters is inferior to heparin and associated with a high rate of thrombosis.

CANADIAN JOURNAL OF KIDNEY HEALTH AND DISEASE (2021)

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Article Nutrition & Dietetics