期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 87, 期 15, 页码 9957-9968出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.2c00954
关键词
-
资金
- National Natural Science Foundation of China [22005229]
- Key Laboratory of Coal Conversion and New Carbon Materials of Hubei Province [WKDM202006]
A different regioselective three-component reaction of alkenes, oxygen sources, and hydroperoxides mediated by ammonium iodine to alpha-oxyperoxidates has been developed. Mechanistic studies showed that regioselective radical addition and subsequent S(N)2 nucleophilic substitution can lead to the formation of products. In addition to the traditional pathway of S(N)2 reaction, an unusual transition configuration involving H2O attacking the alpha-C atom at the front side was also observed.
A different regioselective three-component reaction of alkenes, oxygen sources, and hydroperoxides mediated by ammonium iodine to alpha-oxyperoxidates has been developed. Mechanistic studies demonstrated that regioselective radical addition and subsequent S(N)2 nucleophilic substitution were possible for the formation of products. In addition to the traditional pathway of S(N)2 reaction, that is, where nucleophiles attack the alpha-C atoms at the back side, an additional unusual transition configuration with the H2O molecule attacking the alpha-C atom at the front side was obtained.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据