Photocatalytic Hydroalkylation of Aryl-Alkenes

Here, we present a visible light-catalyzed hydroalkylation of aryl-alkenes affording C-C bonds using aryl-alkenes and alkyl iodides. We demonstrate the formation of various hydroalkylation products in excellent yields, with primary, secondary, and tertiary alkyl iodides being tolerated in the reaction. Mechanistic experiments reveal a pathway consisting of halogen atom transfer followed by a radical-polar crossover mechanism delivering the desired hydroalkylation products.

Automated summary

This research presents a visible light-catalyzed hydroalkylation reaction of aryl-alkenes with alkyl iodides. The reaction demonstrates high yields of various hydroalkylation products, tolerating primary, secondary, and tertiary alkyl iodides. Mechanistic experiments reveal the pathway of halogen atom transfer followed by a radical-polar crossover mechanism.