4.7 Article

Biotin-Targeted Au(I) Radiosensitizer for Cancer Synergistic Therapy by Intervening with Redox Homeostasis and Inducing Ferroptosis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Oncology

Broadening horizons: the role of ferroptosis in cancer

Xin Chen et al.

Summary: Ferroptosis is an iron-dependent form of regulated cell death driven by excessive lipid peroxidation, and can be induced by various agents to suppress tumor growth while also potentially triggering inflammation-associated immunosuppression. The extent of ferroptosis's impact on tumor biology and its interactions with other signaling pathways are still under investigation.

NATURE REVIEWS CLINICAL ONCOLOGY (2021)

Article Chemistry, Medicinal

Developing a Novel Anticancer Gold(III) Agent to Integrate Chemotherapy and Immunotherapy

Juzheng Zhang et al.

Summary: The study developed a metal agent that effectively inhibited gastric tumor growth by targeting two different cellular components in the tumor microenvironment simultaneously, integrating immunotherapy and chemotherapy.

JOURNAL OF MEDICINAL CHEMISTRY (2021)

Article Biochemistry & Molecular Biology

Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer

Laurie Freire Boullosa et al.

Summary: Auranofin (AF), an FDA-approved antirheumatic drug, exhibits anticancer properties by inhibiting TrxR in non-small cell lung cancer cells. Mutant p53 expression enhances sensitivity to AF and leads to various cell death mechanisms including apoptosis and ferroptosis. AF also modulates the innate immune response, enhancing natural killer cell-mediated killing and dendritic cell maturation.

REDOX BIOLOGY (2021)

Article Chemistry, Multidisciplinary

Multifunctional AuI-based AIEgens: Manipulating Molecular Structures and Boosting Specific Cancer Cell Imaging and Theranostics

Zhang Jing et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Biochemistry & Molecular Biology

Chemistry, structure, and biological roles of Au-NHC complexes as TrxR inhibitors

Merve Goksin Karaaslan et al.

BIOORGANIC CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

Anticancer activity of a Gold(I) phosphine thioredoxin reductase inhibitor in multiple myeloma

Jun Hui Sze et al.

REDOX BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin

Amir Ata Saei et al.

REDOX BIOLOGY (2020)

Article Oncology

Cervical Cancer, Version 1.2020 Featured Updates to the NCCN Guidelines

Nadeem R. Abu-Rustum et al.

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2020)

Article Chemistry, Multidisciplinary

Rationally Designed Redox-Active Au(I) N-Heterocyclic Carbene: An Immunogenic Cell Death Inducer

Sajal Sen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Review Chemistry, Inorganic & Nuclear

Advances in alkynyl gold complexes for use as potential anticancer agents

Zhibin Yang et al.

COORDINATION CHEMISTRY REVIEWS (2020)

Article Chemistry, Medicinal

Targeting the Thioredoxin System as a Strategy for Cancer Therapy

Mianli Bian et al.

JOURNAL OF MEDICINAL CHEMISTRY (2019)

Article Chemistry, Multidisciplinary

Enzyme-like Click Catalysis by a Copper-Containing Single-Chain Nanoparticle

Junfeng Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Reversible Covalent and Supramolecular Functionalization of Water-Soluble Gold(I) Complexes

Benedict Kemper et al.

CHEMISTRY-A EUROPEAN JOURNAL (2017)

Review Biochemistry & Molecular Biology

TrxR1 as a Potent Regulator of the Nrf2-Keap1 Response System

Marcus Cebula et al.

ANTIOXIDANTS & REDOX SIGNALING (2015)

Article Chemistry, Multidisciplinary

Heterometallic titanium-gold complexes inhibit renal cancer cells in vitro and in vivo

Jacob Fernandez-Gallardo et al.

CHEMICAL SCIENCE (2015)

Article Chemistry, Medicinal

Design and synthesis of novel photoaffinity probes for study of the target proteins of oleanolic acid

Liying Zhang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Article Cell Biology

Effects of redox modulation by inhibition of thioredoxin reductase on radiosensitivity and gene expression

Markus Selenius et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2012)

Article Chemistry, Organic

Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

Karen Ka-Yan Kung et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2012)

Article Chemistry, Inorganic & Nuclear

The status of platinum anticancer drugs in the clinic and in clinical trials

Nial J. Wheate et al.

DALTON TRANSACTIONS (2010)

Article Chemistry, Medicinal

Benzimidazol-2-ylidene Gold(I) Complexes Are Thioredoxin Reductase Inhibitors with Multiple Antitumor Properties

Riccardo Rubbiani et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Oncology

Thioredoxin and Cancer: A Role for Thioredoxin in all States of Tumor Oxygenation

Therese Christina Karlenius et al.

Cancers (2010)

Article Chemistry, Medicinal

Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies

Stefania Nobili et al.

MEDICINAL RESEARCH REVIEWS (2009)

Review Oncology

The resurgence of platinum-based cancer chemotherapy

Lloyd Kelland

NATURE REVIEWS CANCER (2007)