相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Targeting glucose metabolism to develop anticancer treatments and therapeutic patents
Yan Zhou et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2022)
Discovery of Novel Pyrrolo[2,3-d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors
Xuewu Liang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Activatable Mitochondria-Targeting Organoarsenic Prodrugs for Bioenergetic Cancer Therapy
Xiangjie Luo et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
Mitochondria as a Novel Target for Cancer Chemoprevention: Emergence of Mitochondrial-targeting Agents
Mofei Huang et al.
CANCER PREVENTION RESEARCH (2021)
Antitumor and toxicity study of mitochondria-targeted triptolide derivatives using triphenylphosphine (TPP+) as a carrier
Huina Song et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2021)
A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation
Chaitanya A. Kulkarni et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
A novel selective mitochondrial-targeted curcumin analog with remarkable cytotoxicity in glioma cells
Lei Shi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Dual-Target Inhibitors Based on HDACs: Novel Antitumor Agents for Cancer Therapy
Tingting Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Mitochondrial Relocation of a Common Synthetic Antibiotic: A Non-genotoxic Approach to Cancer Therapy
Kyoung Sunwoo et al.
CHEM (2020)
Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker
Hiran A. Prag et al.
MOLECULAR PHARMACEUTICS (2020)
TPP-based mitocans: a potent strategy for anticancer drug design
Jiayao Wang et al.
RSC MEDICINAL CHEMISTRY (2020)
Mitochondrion-targeted platinum complexes suppressing lung cancer through multiple pathways involving energy metabolism
Zhenzhu Zhu et al.
CHEMICAL SCIENCE (2019)
Rational design of mitochondria-targeted pyruvate dehydrogenase kinase 1 inhibitors with improved selectivity and antiproliferative activity
Biao Xu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Photocatalytic Supramolecular Enantiodifferentiating Dimerization of 2-Anthracenecarboxylic Acid through Triplet-Triplet Annihilation
Ming Rao et al.
ORGANIC LETTERS (2018)
Overcoming Drug Resistance by Targeting Cancer Bioenergetics with an Activatable Prodrug
Amit Sharma et al.
CHEM (2018)
Mitochondria as a therapeutic target for common pathologies
Michael P. Murphy et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity
Jing Pan et al.
ISCIENCE (2018)
Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect
Wen Zhang et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Mitochondria-Targeted Lupane Triterpenoid Derivatives and Their Selective Apoptosis-Inducing Anticancer Mechanisms
Yaqing Ye et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Mitochondria-targeted metformins: anti-tumour and redox signalling mechanisms
Balaraman Kalyanaraman et al.
INTERFACE FOCUS (2017)
Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications
Jacek Zielonka et al.
CHEMICAL REVIEWS (2017)
Unique Triphenylphosphonium Derivatives for Enhanced Mitochondrial Uptake and Photodynamic Therapy
Zhang Hu et al.
BIOCONJUGATE CHEMISTRY (2017)
Mitochondrial diseases
Grainne S. Gorman et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
Uncoupling and toxic action of alkyltriphenylphosphonium cations on mitochondria and the bacterium Bacillus subtilis as a function of alkyl chain length
L. S. Khailova et al.
BIOCHEMISTRY-MOSCOW (2015)
Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents
Shao-Lin Zhang et al.
DRUG DISCOVERY TODAY (2015)
Mitochondrial biology, targets, and drug delivery
Lara Milane et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Lipophilic Triphenylphosphonium Cations Inhibit Mitochondrial Electron Transport Chain and Induce Mitochondrial Proton Leak
Jan Trnka et al.
PLOS ONE (2015)
Mito-DCA: A Mitochondria Targeted Molecular Scaffold for Efficacious Delivery of Metabolic Modulator Dichloroacetate
Rakesh K. Pathak et al.
ACS CHEMICAL BIOLOGY (2014)
Sodium phenylbutyrate decreases plasma branched-chain amino acids in patients with urea cycle disorders
Lindsay C. Burrage et al.
MOLECULAR GENETICS AND METABOLISM (2014)
Mitochondrial form and function
Jonathan R. Friedman et al.
NATURE (2014)
Development of 18F-Labeled Picolinamide Probes for PET Imaging of Malignant Melanoma
Hongguang Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
A Selective Mitochondrial-Targeted Chlorambucil with Remarkable Cytotoxicity in Breast and Pancreatic Cancers
Melissa Millard et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death
Gang Cheng et al.
CANCER RESEARCH (2012)
Oral Availability and Brain Penetration of the B-RAFV600E Inhibitor Vemurafenib Can Be Enhanced by the P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) Inhibitor Elacridar
Selvi Durmus et al.
MOLECULAR PHARMACEUTICS (2012)
Mitochondria-Targeted Small Molecule Therapeutics and Probes
Robin A. J. Smith et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Mitochondrially targeted anti-cancer agents
Lucia Biasutto et al.
MITOCHONDRION (2010)
Targeting mitochondria
Adam T. Hoye et al.
ACCOUNTS OF CHEMICAL RESEARCH (2008)
Effects of targeting moiety, linker, bifunctional chelator, and molecular charge on biological properties of 64Cu-labeled triphenylphosphonium cations
Young-Seung Kim et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Nanoemulsion Preparations of the Anticancer Drug Dacarbazine Significantly Increase Its Efficacy in a Xenograft Mouse Melanoma Model
Jean-Bosco Tagne et al.
MOLECULAR PHARMACEUTICS (2008)