A promising treatment for HIV-1 using biosynthesis of metal nanoparticles

Human immunodeficiency virus (HIV) is the aetiological agent of acquired immunodeficiency disease syndrome (AIDS). A noticeable public health worry is associated with the fast growth of drug resistance to the present treatments and also the drugs with negative side effects because of their long-term use. Lately, there has been a quick progress in using metal nanoparticles (MNPs) due to their anti-virus activ-ities. On the other hand, physicochemical procedures for synthesizing MNPs create some problems owing to use of toxic solvents, high consumption of energy, and formation of non-ecofriendly by-products. Therefore, it is vital to develop environment-friendly methods to synthesize MNPs. This study presents a review of anti-virus effects of MNPs on HIV/AIDS. In addition, we studied the potential of green MNPs especially silver (Ag), gold (Au), and zinc oxide (ZnO) NPs, to supply a method for treating HIV and future challenges.(c) 2022 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.

Automated summary

This article reviews the antiviral effects of metal nanoparticles on HIV/AIDS and explores the potential and future challenges of green nanoparticles for treating HIV.