4.5 Review

The effects of hypertension on the prognosis of coronavirus disease 2019: a systematic review and meta-analysis on the interactions with age and antihypertensive treatment

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Public, Environmental & Occupational Health

Clinical Characteristics and Predictors of Mortality in Minority Patients Hospitalized with COVID-19 Infection

Rizwan Muhammad et al.

Summary: This study found that older patients with elevated markers of inflammation, coagulation, and end-organ damage were at higher risk of mortality. Advanced age, along with specific biomarkers, were independently associated with increased risk of in-hospital mortality in minority patients hospitalized with COVID-19.

JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES (2022)

Article Peripheral Vascular Disease

Renin-Angiotensin-Aldosterone System Inhibitors and COVID-19 Infection or Hospitalization: A Cohort Study

Sascha Dublin et al.

Summary: The study found that individuals using ACEI/ARBs had no significant difference in COVID-19 infection rates and hospitalization rates compared to those not using these medications, and there was no association with medication dose.

AMERICAN JOURNAL OF HYPERTENSION (2021)

Article Endocrinology & Metabolism

Metabolic Syndrome and COVID-19 Mortality Among Adult Black Patients in New Orleans

John Xie et al.

Summary: In patients hospitalized for COVID-19 in New Orleans during the peak of the outbreak, clustering of hypertension, obesity, and diabetes as metabolic syndrome increased the odds of mortality, ICU admission, invasive mechanical ventilation, and acute respiratory distress syndrome compared with these comorbidities individually. Inflammatory biomarkers CRP and LDH associated with MetS were also linked with mortality.

DIABETES CARE (2021)

Article Infectious Diseases

Clinical characteristics of adult patients hospitalized with laboratory-confirmed COVID-19 pneumonia

Elif Sargin Altunok et al.

Summary: The study summarized the clinical characteristics and outcomes of adult patients hospitalized with laboratory-confirmed COVID-19 pneumonia in Istanbul, Turkey. The mortality rate was significantly higher in elderly patients compared to non-elderly patients, with an overall mortality rate of 8.5%.

JOURNAL OF INFECTION AND CHEMOTHERAPY (2021)

Article Medicine, General & Internal

Effects of renin-angiotensin system blockers on the risk and outcomes of severe acute respiratory syndrome coronavirus 2 infection in patients with hypertension

Jinwoo Lee et al.

Summary: The study found that the use of renin-angiotensin system (RAS) blockers may increase the risk of SARS-CoV-2 infection, but is not associated with higher mortality or other severe clinical courses.

KOREAN JOURNAL OF INTERNAL MEDICINE (2021)

Article Medicine, General & Internal

Update on association between exposure to renin-angiotensin-aldosterone system inhibitors and coronavirus disease 2019 in South Korea

Jeongkuk Seo et al.

Summary: The study found no evidence of an association between exposure to RAAS inhibitors and the risk and severity of COVID-19.

KOREAN JOURNAL OF INTERNAL MEDICINE (2021)

Article Rheumatology

Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients

Florence Aeschlimann et al.

Summary: In this French cohort study of RMD COVID-19 patients, older age, male gender, obesity, and hypertension were found to be associated with severe COVID-19, similar to the general population. Patients with iRMD on corticosteroids, but not methotrexate, tumor necrosis factor alpha, and interleukin-6 inhibitors, were more likely to develop severe COVID-19. Unlike common comorbidities, such as obesity, cardiovascular or lung diseases, the risk of death in patients with iRMD was not significantly increased.

ANNALS OF THE RHEUMATIC DISEASES (2021)

Article Medicine, Research & Experimental

Hypertension, Diabetes and Obesity, Major Risk Factors for Death in Patients with COVID-19 in Mexico

Jorge Escobedo-de la Pena et al.

Summary: The study investigated the main clinical characteristics of COVID-19 in a major social security institution in Mexico, finding that major cardiovascular risk factors and other comorbidities increased the risk of mortality in patients with COVID-19. Factors such as age, sex, obesity, hypertension, and diabetes were associated with an increased case fatality rate.

ARCHIVES OF MEDICAL RESEARCH (2021)

Article Medicine, General & Internal

Chronic comorbidities and clinical outcomes in patients with and without COVID-19: a large population-based study using national administrative healthcare open data of Mexico

Frank Daniel Martos-Benitez et al.

Summary: This study analyzed data from Mexico to investigate the impact of chronic comorbidities on clinical outcomes of patients with suspected or confirmed COVID-19. It found that chronic comorbidities were common in these patients and influenced outcomes such as hospitalization, pneumonia, ICU admission, intubation, and mortality. Understanding the effects of comorbidities on clinical outcomes can help identify high-risk COVID-19 patients, and further research is needed to explore the specific impact of different types of chronic comorbidities in patients with and without SARS-CoV-2 infection.

INTERNAL AND EMERGENCY MEDICINE (2021)

News Item Cardiac & Cardiovascular Systems

Can ACEIs and ARBs be safely continued in COVID-19:- The Evidence is here at Last!

Uma Velupandian

HEART VIEWS (2021)

Article Peripheral Vascular Disease

Independent and combined effects of hypertension and diabetes on clinical outcomes in patients with COVID-19: A retrospective cohort study of Huoshen Mountain Hospital and Guanggu Fangcang Shelter Hospital

Yuhui Sun et al.

Summary: This study found that T2DM is a significant risk factor for death, ARDS/respiratory failure, and severe COVID-19 infection, while hypertension only presents additional risk for the development of severe infection. Hypertension is not an independent risk factor for death or ARDS/respiratory failure but marginally increases the risk of severe COVID-19 infection, accentuated through its confounding effect on T2DM.

JOURNAL OF CLINICAL HYPERTENSION (2021)

Article Medicine, General & Internal

Outcomes for patients with COVID-19 admitted to Australian intensive care units during the first four months of the pandemic

Aidan J. C. Burrell et al.

Summary: The study of COVID-19 patients admitted to ICUs in Australia revealed that patients mostly acquired the virus through overseas travel, with common comorbidities being obesity, diabetes, and hypertension. Patients requiring invasive ventilation had longer ICU stay and higher mortality rates.

MEDICAL JOURNAL OF AUSTRALIA (2021)

Article Biotechnology & Applied Microbiology

Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19

Saskia Trump et al.

Summary: Single-cell analysis reveals the impact of ACEI and ARB treatments on COVID-19 progression in patients with hypertension. ACEI treatment is associated with dampened inflammation and enhanced antiviral responses, while ARB treatment is related to increased epithelial-immune cell interactions, suggesting further investigation is warranted for the clinical benefits of ACEI treatment in this patient population.

NATURE BIOTECHNOLOGY (2021)

Article Infectious Diseases

Outcomes and prognostic factors in 70 non-survivors and 595 survivors with COVID-19 in Wuhan, China

Mingyu Liu et al.

Summary: The study confirmed that risk factors such as older age, diabetes, dyspnoea, respiratory failure, acute cardiac injury, and acute respiratory distress syndrome were associated with in-hospital fatal outcome of COVID-19. Additionally, older age, diabetes, cardiovascular disease, nervous system disease, dyspnoea, achieving high in-hospital temperature of >39.0 degrees C, and longer onset of illness to diagnosis were statistically linked to a higher risk of developing severe COVID-19.

TRANSBOUNDARY AND EMERGING DISEASES (2021)

Article Endocrinology & Metabolism

Metabolic syndrome and clinical outcomes in patients infected with COVID-19: Does age, sex, and race of the patient with metabolic syndrome matter?

Prateek Lohia et al.

Summary: This study found an association between metabolic syndrome (MetS) and severe disease outcomes in patients with COVID-19, including increased mortality, ICU admission, and need for mechanical ventilation. Patients with MetS had significantly higher mortality rates, increased ICU admissions, and greater need for mechanical ventilation compared to those without MetS.

JOURNAL OF DIABETES (2021)

Article Biotechnology & Applied Microbiology

Acute Kidney Injury in Hospitalized Patients Infected with COVID-19 from Wuhan, China: A Retrospective Study

Yujie Dai et al.

Summary: This study investigated the risk factors of acute kidney injury (AKI) in patients infected with the novel coronavirus, and found that male sex, chronic kidney disease, hypertension, increased leukocytes, and diuretic use were independent risk factors for AKI in SARS-CoV-2 infected patients. Patients with AKI had higher mortality rates.

BIOMED RESEARCH INTERNATIONAL (2021)

Article Endocrinology & Metabolism

Metformin Use Is Associated With Reduced Mortality in a Diverse Population With COVID-19 and Diabetes

Andrew B. Crouse et al.

Summary: The study found that Black/African-Americans, obesity, hypertension, and diabetes were associated with higher likelihood of contracting COVID-19. Diabetes was also linked to a dramatic increase in COVID-19-related mortality, but the use of metformin showed a significant reduction in mortality for diabetic individuals with COVID-19.

FRONTIERS IN ENDOCRINOLOGY (2021)

Article Medicine, General & Internal

Effect of Sex on Clinical Outcomes in Patients with Coronavirus Disease: A Population-Based Study

Kyu Hyang Cho et al.

Summary: This population-based study evaluated the association between sex and clinical outcomes in patients with COVID-19, finding that female patients had more favorable outcomes, especially in patients aged 50-64 or >= 65 years. Subgroup analyses showed that women had better survival or clinical outcomes compared to men in terms of age, diabetes mellitus, or hypertension.

JOURNAL OF CLINICAL MEDICINE (2021)

Article Medicine, General & Internal

The nutritional status of the elderly patient infected with COVID-19: the forgotten risk factor?

Jessica Abadia Otero et al.

Summary: This study evaluated the nutritional status of patients over 65 years old admitted due to COVID-19, finding that malnutrition was a significant risk factor for mortality, comparable to factors like hypertension, age, and comorbidities. It highlights the importance of assessing and treating the nutritional status of elderly COVID-19 patients to improve their outcomes.

CURRENT MEDICAL RESEARCH AND OPINION (2021)

Article Multidisciplinary Sciences

In-hospital mortality from severe COVID-19 in a tertiary care center in Mexico City; causes of death, risk factors and the impact of hospital saturation

Antonio Olivas-Martinez et al.

Summary: The high in-hospital death rate among severe COVID-19 patients in Mexico is associated with risk factors such as male sex, obesity, and low oxygen saturation on admission. Lack of ICU beds resulted in some patients not receiving necessary support, indirectly contributing to hospital mortality.

PLOS ONE (2021)

Article Medicine, General & Internal

Clinical Characteristics and Outcomes of COVID-19 Cohort Patients in Daegu Metropolitan City Outbreak in 2020

Shin-Woo Kim et al.

Summary: The COVID-19 outbreak in Daegu, Korea was controlled by the end of March 2020. A retrospective, multicenter cohort study conducted on 7,057 laboratory-confirmed patients revealed that 77% were asymptomatic to mild. Key risk factors for 28-day mortality included age, need for O-2 supply, fever, and underlying health conditions like diabetes and cancer.

JOURNAL OF KOREAN MEDICAL SCIENCE (2021)

Article Endocrinology & Metabolism

High prevalence of diabetes and other comorbidities in hospitalized patients with COVID-19 in Delhi, India, and their association with outcomes

Ambrish Mithal et al.

Summary: A study on hospitalized COVID-19 patients found a high prevalence of diabetes, with diabetes and hypertension associated with more severe disease and higher mortality rates.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2021)

Editorial Material Cardiac & Cardiovascular Systems

COVID-19: (mis)managing an announced Black Swan

Thomas F. Luescher

EUROPEAN HEART JOURNAL (2020)

Article Allergy

Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan

Xiaochen Li et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Letter Critical Care Medicine

Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?

Lei Fang et al.

LANCET RESPIRATORY MEDICINE (2020)

Article Peripheral Vascular Disease

Use of RAAS Inhibitors and Risk of Clinical Deterioration in COVID-19: Results From an Italian Cohort of 133 Hypertensives

Carla Felice et al.

AMERICAN JOURNAL OF HYPERTENSION (2020)

Article Medicine, General & Internal

Demographics, comorbidities and outcomes in hospitalized Covid-19 patients in rural southwest Georgia

Priyank Shah et al.

ANNALS OF MEDICINE (2020)

Article Pharmacology & Pharmacy

Is the use of ACE inb/ARBs associated with higher in-hospital mortality in Covid-19 pneumonia patients?

Murat Selcuk et al.

CLINICAL AND EXPERIMENTAL HYPERTENSION (2020)

Article Medicine, Research & Experimental

Increased Risk of Hospitalization and Death in Patients with COVID-19 and Pre-existing Noncommunicable Diseases and Modifiable Risk Factors in Mexico

Diego Rolando Hernandez-Galdamez et al.

ARCHIVES OF MEDICAL RESEARCH (2020)

Article Endocrinology & Metabolism

Risk factors for mortality among COVID-19 patients

Orwa Albitar et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2020)

Article Medicine, General & Internal

Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US

Shruti Gupta et al.

JAMA INTERNAL MEDICINE (2020)

Article Emergency Medicine

Predictors of Mortality in Adults Admitted with COVID-19: Retrospective Cohort Study from New York City

Sridhar Chilimuri et al.

WESTERN JOURNAL OF EMERGENCY MEDICINE (2020)

Article Cardiac & Cardiovascular Systems

Mortality Risk Assessment Using CHA(2)DS(2)-VASc Scores in Patients Hospitalized With Coronavirus Disease 2019 Infection

Gaetano Ruocco et al.

AMERICAN JOURNAL OF CARDIOLOGY (2020)

Article Geriatrics & Gerontology

Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort

Janice L. Atkins et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)

Article Multidisciplinary Sciences

Factors associated with COVID-19-related death using OpenSAFELY

Elizabeth J. Williamson et al.

NATURE (2020)

Article Multidisciplinary Sciences

Early estimation of the risk factors for hospitalization and mortality by COVID-19 in Mexico

Maria Fernanda Carrillo-Vega et al.

PLOS ONE (2020)

Article Medicine, General & Internal

The Efficacy of the Mineralcorticoid Receptor Antagonist Canrenone in COVID-19 Patients

Marco Vicenzi et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Infectious Diseases

The potential role of serum angiotensin-converting enzyme in coronavirus disease 2019

Zhe Zhu et al.

BMC INFECTIOUS DISEASES (2020)

Article Public, Environmental & Occupational Health

Patient characteristics and predictors of mortality in 470 adults admitted to a district general hospital in England with Covid-19

J. Thompson et al.

EPIDEMIOLOGY AND INFECTION (2020)

Review Immunology

The trinity of COVID-19: immunity, inflammation and intervention

Matthew Zirui Tay et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Medicine, General & Internal

Impact of antihypertensive agents on clinical course and in-hospital mortality: analysis of 169 hypertensive patients hospitalized for COVID-19

Ibrahim Kocayigit et al.

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA (2020)

Editorial Material Cardiac & Cardiovascular Systems

COVID-19: (mis)managing an announced Black Swan

Thomas F. Luescher

EUROPEAN HEART JOURNAL (2020)

Article Peripheral Vascular Disease

Urinary Angiotensin-Converting Enzyme 2 in Hypertensive Patients May Be Increased by Olmesartan, an Angiotensin II Receptor Blocker

Masato Furuhashi et al.

AMERICAN JOURNAL OF HYPERTENSION (2015)

Review Peripheral Vascular Disease

Inflammation, Immunity, and Hypertension

David G. Harrison et al.

HYPERTENSION (2011)

Review Cardiac & Cardiovascular Systems

Vascular Inflammation and Endothelial Dysfunction in Experimental Hypertension

Carmine Savoia et al.

INTERNATIONAL JOURNAL OF HYPERTENSION (2011)