期刊
JOURNAL OF CONTROLLED RELEASE
卷 224, 期 -, 页码 146-157出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jconrel.2015.12.046
关键词
Cyclodextrin; Textile fabric; Drug release; Skin disorders
资金
- European Social Fund within the Sectorial Operational Program Human Resources Development [POSDRU/159/1.5/S/133652]
This paper presents data on the general properties and complexing ability of cyclodextrins and assessment methods (phase solubility, DSC tests and X-ray diffraction, FTIR spectra, analytical method). It focuses on the formation of drug deposits on the surface of a textile underlayer, using a cyclodextrin compound favoring the inclusion of a drug/active principle and its release onto the dermis of patients suffering from skin disorders, or for protection against insects. Moreover, it presents the kinetics, duration, diffusion flow and release media of the cyclodextrin drug for in vitro studies, as well as the release modeling of the active principle. The information focuses on therapies: antibacterial, anti-allergic, antifungal, chronic venous insufficiency, psoriasis and protection against insects. The pharmacodynamic agents/active ingredients used on cotton, woolen and synthetic textile fabrics are presented. (C) 2016 Elsevier B.V. All rights reserved.
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