期刊
JOURNAL OF CONTROLLED RELEASE
卷 225, 期 -, 页码 1-30出版社
ELSEVIER
DOI: 10.1016/j.jconrel.2016.01.018
关键词
Curcumin; Curcuminoids; Drug delivery; Nanocarriers
Curcumin and its derivatives; curcuminoids have been proven as potential remedies in different diseases. However, their delivery carries several challenges owing to their poor aqueous solubility, photodegradation, chemical instability, poor bioavailability and rapid metabolism. This review explores and criticizes the numerous attempts that were adopted through the years to entrap/encapsulate this valuable drug in nanocarriers aiming to reach its most appropriate and successful delivery system. (C) 2016 Elsevier B.V. All rights reserved.
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