4.6 Article

Quantification and characterization of mineral oil in fish feed by liquid chromatography-gas chromatography-flame ionization detector and liquid chromatography-comprehensive multidimensional gas chromatography-time-of-flight mass spectrometer/flame ionization detector

期刊

JOURNAL OF CHROMATOGRAPHY A
卷 1677, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.chroma.2022.463208

关键词

Mineral oil saturated hydrocarbons (MOSH); Mineral oil aromatic hydrocarbons (MOAH); Comprehensive two-dimensional gas chromatography (GC x GC); Liquid-gas chromatography (LC-GC)

资金

  1. Division of Analytical Chemistry of the European Chemical Society
  2. Fonds de la Recherche Scientifique Belgique (FNRS) (CDR projects-MOH Platform) [J.0170.20]
  3. LECO
  4. Restek

向作者/读者索取更多资源

This study analyzed seven commercial feeds and found consistent results between two laboratories. The combination of liquid-gas chromatography and liquid chromatography coupled with comprehensive multidimensional gas chromatography, along with parallel detection using flame ionization detector and time-of-flight mass spectrometer, allowed for a more comprehensive characterization of the contaminants.
Mineral oil is an ubiquitous food contaminant potentially toxic. It is generally divided into aromatic hydrocarbons (MOAH) and saturated hydrocarbons (MOSH). These compounds are currently under investigation by the European Union to determine their occurrence and their toxicity before legislating on the matter. Although the discussion mainly focuses on food, animal feed can indirectly contribute to human exposure to such a contaminant. In this study, seven commercial feeds were analyzed. The analyses were carried out in two different Universities (Udine-IT and Liege-BE), performing the same sample preparation protocol: microwave-assisted saponification and extraction followed by epoxidation for the MOAH fraction. The final determination was performed by hyphenated liquid-gas chromatography (LC-GC) and LC coupled to comprehensive multidimensional gas chromatography (LC-GC x GC) with parallel detection, namely flame ionization detector (FID) and time-of-flight mass spectrometer (ToFMS). The results obtained by the two laboratories were generally in good agreement. The results obtained by LC-GC x GC-ToFMS/FID platform provided consistent results, with the advantages of more robust data interpretation that can compensate for problems occurring during purification. Moreover, the coupling of enhanced separation obtained by GC x GC and the MS information allowed for a more in-depth characterization of the contamination. (C) 2022 Elsevier B.V. All rights reserved.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据