Recent advances in sonodynamic immunotherapy

Tumor immunotherapy has become an important means of tumor therapy by enhancing the immune response and triggering the activation of immune cells. However, currently, only a small number of patients respond to immunotherapy alone, and patients may experience immune-related adverse events (irAEs) during the course of treatment. Sonodynamic therapy (SDT) can produce cytotoxic substances to tumor tissue, induce apoptosis and enhance immunity. SDT combined with immunotherapy is considered a promising strategy for cancer treatment. In this mini review, we summarize the role of SDT in immunotherapy in recent years, including the application of SDT-triggered immunotherapy and the combination of SDT and immunotherapy.

Automated summary

Tumor immunotherapy, which enhances the immune response and activates immune cells, has become an important approach in tumor therapy. Sonodynamic therapy, which produces cytotoxic substances to tumor tissue, induces apoptosis, and enhances immunity, combined with immunotherapy, shows promise as a strategy for cancer treatment.