4.6 Article

Continued adjuvant FOLFIRINOX for BRPC or LAPC after neoadjuvant FOLFIRINOX

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Surgery

Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer

Ulla Klaiber et al.

Summary: In patients undergoing resection after neoadjuvant therapy for initially unresectable PDAC, preoperative CA 19-9 levels, lymph node involvement, metastasis category, and vascular involvement, but not the R status, were independent prognostic factors of overall survival.

ANNALS OF SURGERY (2021)

Article Surgery

Surgery Improves Survival After Neoadjuvant Therapy for Borderline and Locally Advanced Pancreatic Cancer A Single Institution Experience

Elena Rangelova et al.

Summary: Neoadjuvant therapy (NAT) has become an important part of the treatment for borderline resectable pancreatic cancer (BRPC) and locally advanced pancreatic cancer (LAPC). Surgical resection should be considered for all patients with BRPC/LAPC who do not progress during NAT, regardless of the type or dose of NAT given. Higher Ca 19-9 levels should not be considered an absolute contraindication for resection.

ANNALS OF SURGERY (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Survival in borderline resectable and locally advanced pancreatic cancer is determined by the duration and response of neoadjuvant therapy

Asanka R. Wijetunga et al.

Summary: This study investigated the effects of neoadjuvant treatment on overall survival and recurrence-free survival in BRPC and LAPC pancreatic cancer patients, finding that patients who respond to NAT likely have a favorable disease biology and will progress well following resection. Therefore, these patients should be selected for more aggressive upfront management.
Article Oncology

Pancreatic Adenocarcinoma, Version 2.2021

Margaret A. Tempero et al.

Summary: Pancreatic cancer is the fourth leading cause of cancer-related death in the United States, with a major challenge being advanced disease at diagnosis. While survival rates have not significantly changed, newer treatments, including targeted therapies, offer hope for patients. The manuscript focuses on systemic therapy approaches for locally advanced and metastatic disease.

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2021)

Article Medicine, General & Internal

FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer

T. Conroy et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Editorial Material Oncology

Pancreatic Adenocarcinoma: Treating a Systemic Disease With Systemic Therapy

Davendra P. S. Sohal et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2014)

Review Medicine, General & Internal

Pancreatic Adenocarcinoma

David P. Ryan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Medicine, General & Internal

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

Thierry Conroy et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)