期刊
JOURNAL OF BIOMATERIALS APPLICATIONS
卷 37, 期 5, 页码 930-941出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/08853282221121886
关键词
Micro-arc oxidation; magnesium alloy; yttrium; corrosion resistance; cytocompatibility
资金
- Natural Foundation of Gansu Province, China [1208RJZA236]
- Key Technology Support Program of Gansu Province, China [1604FKCA089]
- Key Technology Plan Program of Gansu Province, China [20YF8FA071]
This study aimed to improve the corrosion resistance and biocompatibility of AZ31 magnesium alloys and prepare degradable implant materials. Micro-arc oxidation (MAO) was used to prepare coatings with different yttrium content on the surface of AZ31 magnesium alloy. The results showed that the yttrium-doped coating significantly improved the corrosion resistance of magnesium alloys and had good biocompatibility. The concentration of 0.0035 mol/L resulted in the highest corrosion resistance of the coating.
The rapid degradation characteristics of magnesium alloys limit its application in the field of orthopedic fracture fixation and cardiovascular stents. This study aimed to improve the corrosion resistance and biocompatibility of AZ31 magnesium alloys and prepare degradable implant materials. Micro-arc oxidation (MAO) was used to change the concentration of yttrium acetate in the electrolyte to prepare coatings with different yttrium content on the surface of AZ31 magnesium alloy. Through characterization, it is proved that the yttrium in the coating mainly exists in the form of Y3+. The polarization potential experiment shows that the micro-arc oxidation coating significantly improves the corrosion resistance of magnesium alloys. With the increase of yttrium acetate concentration in the electrolyte, the corrosion resistance of the coating first increases and then weakens. When the concentration is 0.0035 mol/L, the coating has the highest corrosion resistance. The results of CCK-8 cytotoxicity experiment and cell morphology observation also proved that the cell viability in each group was greater than 140%, and the yttrium-doped coating on the surface of AZ31 magnesium alloy has no cytotoxicity, can promote cell growth, and has good biocompatibility.
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