Cost utility of vitamin D supplementation in adults with mild to moderate asthma

Article Allergy

Cost-utility of azithromycin in patients with severe asthma

Jefferson Antonio Buendia et al.

Summary: The study found that add-on therapy with azithromycin is cost-effective for asthma patients who remain uncontrolled despite treatment with medium or high-dose ICS/LABA.

JOURNAL OF ASTHMA (2022)

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Article Allergy

Cost-effectiveness of tiotropium versus omalizumab for uncontrolled allergic asthma

Jefferson Antonio Buendia et al.

Summary: The study found that tiotropium is a cost-effective alternative to omalizumab and standard therapy for uncontrolled allergic asthma, with lower cost and higher quality-adjusted life years. Decision-makers should consider these results to improve clinical practice guidelines and further research in other middle-income countries.

JOURNAL OF ASTHMA (2022)

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Article Health Care Sciences & Services

Cost-utility analysis and budget impact of benralizumab as add-on therapy to standard care for severe eosinophilic asthma in Colombia

Buendia Jefferson Antonio et al.

Summary: The study analyzed the cost-utility of benralizumab treatment in adults with severe uncontrolled asthma in Colombia. The results showed that benralizumab would be cost-effective if its cost is reduced by 41% at an incremental cost-effectiveness ratio of $42,746 per QALY gained.

EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH (2022)

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Review Respiratory System

Vitamin D supplementation in childhood asthma: a systematic review and meta-analysis of randomised controlled trials

Jogender Kumar et al.

Summary: The efficacy of vitamin D supplementation in childhood asthma remains uncertain. This study found that vitamin D supplementation did not significantly reduce asthma attacks, emergency visits, or hospitalization in children with asthma.

ERJ OPEN RESEARCH (2022)

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Article Health Care Sciences & Services

Estimating cost-effectiveness thresholds under a managed healthcare system: experiences from Colombia

Oscar Espinosa et al.

Summary: This study examined the healthcare system of the middle-income country Colombia, estimating the cost-effectiveness threshold and exploring the variation of health expenditures and outcomes. The threshold was found to be around one times the GDP per capita, providing valuable insights for decision-making in a managed healthcare system.

HEALTH POLICY AND PLANNING (2022)

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Review Medicine, General & Internal

Vitamin D supplementation in pregnant women or infants for preventing allergic diseases: a systematic review and meta-analysis of randomized controlled trials

Chao Luo et al.

Summary: The efficacy of vitamin D supplementation in pregnant women, infants, or children for the prevention of allergies was reviewed in this study. The findings suggest that vitamin D supplementation does not have a significant effect on the primary prevention of allergic diseases.

CHINESE MEDICAL JOURNAL (2022)

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Article Respiratory System

Cost-utility of triple versus dual inhaler therapy in moderate to severe asthma

Jefferson Antonio Buendia et al.

Summary: The study found that triple therapy is cost-effective compared to dual therapy for patients with severe asthma, with a potential gain of 1.55 QALYs per patient per year. Sensitivity analysis showed that the base-case results were robust to variations in assumptions and parameters.

BMC PULMONARY MEDICINE (2021)

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Article Respiratory System

Cost-utility of as-needed ICS-formoterol versus to maintenance ICS in mild to moderate persistent asthma

Jefferson Antonio Buendia et al.

Summary: The study concludes that low-dose budesonide-formoterol as a reliever is cost-effective for patients with mild asthma, with potential gain in quality-adjusted life-years and reduced costs compared to maintenance ICS therapy. The results were robust in sensitivity analyses, suggesting that this approach could be beneficial for improving clinical practice guidelines and should be validated in other middle-income countries.

BMC PULMONARY MEDICINE (2021)

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Review Nutrition & Dietetics

Vitamin D can safely reduce asthma exacerbations among corticosteroid-using children and adults with asthma: a systematic review and meta-analysis of randomized controlled trials

Ziyu Chen et al.

Summary: Vitamin D supplementation significantly reduces the risk of asthma exacerbation, but does not have a clear effect on improving ACT score or lung function in patients with asthma.

NUTRITION RESEARCH (2021)

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Editorial Material Economics