4.7 Article Proceedings Paper

Effect of Omecamtiv Mecarbil on Exercise Capacity in Chronic Heart Failure With Reduced Ejection Fraction The METEORIC-HF Randomized Clinical Trial

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Letter Cardiac & Cardiovascular Systems

Physical Activity Among Patients With Intracardiac Remote Monitoring Devices Before, During, and After COVID-19-Related Restrictions

Yuan Lu et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

Article Cardiac & Cardiovascular Systems

Assessment of Omecamtiv Mecarbil for the Treatment of Patients With Severe Heart Failure A Post Hoc Analysis of Data From the GALACTIC-HF Randomized Clinical Trial

G. Michael Felker et al.

Summary: This study evaluated the efficacy and safety of omecamtiv mecarbil for severe heart failure patients. The results suggest that omecamtiv mecarbil therapy may have clinically meaningful benefits for patients with severe heart failure, supporting its potential role in patients with limited treatment options.

JAMA CARDIOLOGY (2022)

Article Cardiac & Cardiovascular Systems

Developments in Exercise Capacity Assessment in Heart Failure Clinical Trials and the Rationale for the Design of METEORIC-HF

Gregory D. Lewis et al.

Summary: Heart failure with reduced ejection fraction (HFrEF) is a serious condition characterized by exercise intolerance. The assessment methods for exercise capacity in HFrEF vary widely. Omecamtiv mecarbil, a novel cardiac myosin activator, has shown promising results in improving cardiac contractility and reducing heart failure events in HFrEF patients. The METEORIC-HF trial aims to evaluate the impact of omecamtiv mecarbil on various measures of functional capacity in HFrEF patients.

CIRCULATION-HEART FAILURE (2022)

Article Medicine, General & Internal

Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure

John R. Teerlink et al.

Summary: Among patients with heart failure and reduced ejection fraction, those who received omecamtiv mecarbil had a lower incidence of heart-failure events or cardiovascular death compared to those who received placebo over a median of 22 months.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Cardiac & Cardiovascular Systems

Heart Disease and Stroke Statistics-2021 Update A Report From the American Heart Association

Salim S. Virani et al.

Summary: The American Heart Association, in partnership with the National Institutes of Health, publishes annual statistics on heart disease, stroke, and cardiovascular risk factors, including the impact of health behaviors and factors on cardiovascular health. The Statistical Update covers a range of clinical heart and circulatory conditions, providing data on quality of care, procedures, and economic costs. It serves as a critical resource for various stakeholders seeking the best available data on these factors and conditions.

CIRCULATION (2021)

Article Cardiac & Cardiovascular Systems

Effect of Ejection Fraction on Clinical Outcomes in Patients Treated With Omecamtiv Mecarbil in GALACTIC-HF

John R. Teerlink et al.

Summary: In heart failure patients, omecamtiv mecarbil produces greater therapeutic benefit as baseline ejection fraction decreases, particularly in patients with lower baseline EF.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

Article Medicine, General & Internal

Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction

Paul W. Armstrong et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Cardiac & Cardiovascular Systems

Cardiopulmonary Exercise Testing in Heart Failure

Rajeev Malhotra et al.

JACC-HEART FAILURE (2016)

Article Cardiac & Cardiovascular Systems

Iron deficiency in chronic heart failure: An international pooled analysis

IJsbrand T. Klip et al.

AMERICAN HEART JOURNAL (2013)

Article Multidisciplinary Sciences

Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure

Fady I. Malik et al.

SCIENCE (2011)

Article Cardiac & Cardiovascular Systems

Impact of Cardiac Contractility Modulation on Left Ventricular Global and Regional Function and Remodeling

Cheuk-Man Yu et al.

JACC-CARDIOVASCULAR IMAGING (2009)

Article Medicine, General & Internal

Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure

DW Kitzman et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)