4.7 Article

Endothelium-Dependent Induction of Vasculogenic Mimicry in Human Triple-Negative Breast Cancer Cells Is Inhibited by Calcitriol and Curcumin

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Vitamin D Exerts Significant Antitumor Effects by Suppressing Vasculogenic Mimicry in Breast Cancer Cells

Khuloud Bajbouj et al.

Summary: This study demonstrates that vitamin D exerts its anti-tumor effects in BC cells by inhibiting and curtailing their potential for VM formation.

FRONTIERS IN ONCOLOGY (2022)

Article Oncology

IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways

Muhammad Azhar Nisar et al.

Summary: The study revealed that IL-1 beta promotes vascular mimicry in breast cancer cells by increasing the expression of VM biomarkers, activating the AP-1 complex, and involving the p38/MAPK and PI3K/Akt signaling pathways. Furthermore, the downregulation of VM biomarkers and reduced formation of intersections confirmed the involvement of these pathways in IL-1 beta stimulation.

FRONTIERS IN ONCOLOGY (2021)

Review Cell Biology

Vasculogenic Mimicry in Breast Cancer: Clinical Relevance and Drivers

Gabriela Morales-Guadarrama et al.

Summary: In solid tumors, vasculogenic mimicry (VM) involves the formation of vascular structures by cancer cells, contributing to tumor neovascularization, promoting metastasis, and driving resistance to antiangiogenic therapy. Various factors, including hypoxia and specific genes, play a role in this process.
Article Endocrinology & Metabolism

Vitamin D and Breast Cancer: Mechanistic Update

JoEllen Welsh

Summary: Studies have found that the vitamin D receptor plays a role in the mammary gland and breast cancer, with its ligand 1,25-dihydroxyvitamin D modulating normal mammary gland development and inhibiting tumor growth. Vitamin D deficiency may increase the risk of breast cancer development or progression. However, further research is needed to understand the mechanisms of vitamin D action and potential targets in breast cancer.

JBMR PLUS (2021)

Review Oncology

Targeting the PI3-kinase pathway in triple-negative breast cancer

J. Pascual et al.

ANNALS OF ONCOLOGY (2019)

Review Hematology

Vitamin D in hematological disorders and malignancies

Paige M. Kulling et al.

EUROPEAN JOURNAL OF HAEMATOLOGY (2017)

Article Biotechnology & Applied Microbiology

Epithelial Mesenchymal Transition and Vascular Mimicry in Breast Cancer Stem Cells

Srishti Kotiyal et al.

CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION (2015)

Article Biochemistry & Molecular Biology

Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters

Jayne Loughery et al.

NUCLEIC ACIDS RESEARCH (2014)

Review Oncology

GSK-3 as potential target for therapeutic irvention in cancer

James A. McCubrey et al.

ONCOTARGET (2014)

Article Biochemistry & Molecular Biology

Axl is essential for VEGF-A-dependent activation of PI3K/Akt

Guo-Xiang Ruan et al.

EMBO JOURNAL (2012)

Review Neurosciences

PI3K/AKT/mTOR pathway in angiogenesis

Jayashree Karar et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2011)

Article Biochemistry & Molecular Biology

Inhibition of glycogen synthase kinase by curcumin: Investigation by simulated molecular docking and subsequent in vitro/in vivo evaluation

Yasser Bustanji et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Biologic sequelae of interleukin-6 induced P13-K/Akt signaling in multiple myeloma

T Hideshima et al.

ONCOGENE (2001)