4.7 Article

Metabolomic Profiling of Angiotensin-II-Induced Abdominal Aortic Aneurysm in Ldlr-/- Mice Points to Alteration of Nitric Oxide, Lipid, and Energy Metabolisms

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Medicinal

Block-wise exploration of molecular descriptors with Multi-block Orthogonal Component Analysis (MOCA)

Sebastian Schmidt et al.

Summary: MOCA is an analytical tool for exploring data structures organized in blocks, identifying unique principal components in different blocks and uncovering relationships between blocks and overall trends in the dataset. It proposes a quantitative metric for measuring the redundancy of blocks, useful for feature selection and evaluation of new molecular representations. Additionally, MOCA can help discover general trends in datasets and link them to molecular properties.

MOLECULAR INFORMATICS (2022)

Article Nutrition & Dietetics

Glutamine supplementation can reduce some atherosclerosis markers after exhaustive exercise in young healthy males

Reza Alipanah-Moghadam et al.

Summary: This study investigated the effects of glutamine supplementation on atherosclerosis markers in young healthy males after exhaustive exercise. The results showed that serum levels of certain markers were significantly lower in the intervention group compared to the control group after glutamine supplementation. Additionally, levels of serum markers and the ratio of oxidized low-density lipoprotein to high-density lipoprotein decreased significantly in the intervention group after exhaustive exercise.

NUTRITION (2022)

Article Cardiac & Cardiovascular Systems

Metabolomic Profile Reveals That Ceramide Metabolic Disturbance Plays an Important Role in Thoracic Aortic Dissection

Hang Yang et al.

Summary: The study revealed that ceramide metabolism disturbance might play a vital role in the development of thoracic aortic aneurysm and dissection by aggravating aortic inflammation through the NLRP3 pathway, potentially providing a new target for pharmacological therapy and a potential biomarker of these diseases.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

Article Surgery

Lysophosphatidic Acid May Be a Novel Biomarker for Early Acute Aortic Dissection

Xiaogao Pan et al.

Summary: Lysophosphatidic acid (LPA) is significantly elevated in patients with acute aortic dissection (AAD) and can differentiate sudden-onset acute chest pain. LPA peaks at 12 hours after symptom onset and gradually decreases from 12 to 48 hours. LPA has superior diagnostic performance compared to D-dimer.

FRONTIERS IN SURGERY (2022)

Article Peripheral Vascular Disease

Upregulated Kynurenine Pathway Enzymes in Aortic Atherosclerotic Aneurysm: Macrophage Kynureninase Downregulates Inflammation

Masanori Nishimura et al.

Summary: This study identified an upregulation of the kynurenine pathway in macrophages in aortic atherosclerotic aneurysm. Kynureninase may negatively regulate inflammation via the kynurenine pathway itself in macrophages. The altered levels of tryptophan, kynurenine, and quinolinic acid in aneurysmal walls were also observed.

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2021)

Article Cardiac & Cardiovascular Systems

The short-term safety and effectiveness of a new distal perforating stent graft in Type B aortic dissection: a retrospective study

Xunqiang Liu et al.

Summary: This study retrospectively analyzed the short-term safety and effectiveness of the Talos stent in 20 TBAD patients, showing that the Talos stent had a high technical success rate and achieved satisfactory clinical treatment results without severe complications.

BMC CARDIOVASCULAR DISORDERS (2021)

Review Physiology

Branched-chain Amino Acids: Catabolism in Skeletal Muscle and Implications for Muscle and Whole-body Metabolism

Gagandeep Mann et al.

Summary: BCAAs are crucial for skeletal muscle and whole-body anabolism and energy balance, but elevated levels and impaired metabolism may lead to chronic diseases like insulin resistance. Research is focusing on mechanisms regulating BCAA metabolism and its impact on muscle and whole-body metabolism.

FRONTIERS IN PHYSIOLOGY (2021)

Article Biochemistry & Molecular Biology

Metabolomic Profile of Abdominal Aortic Aneurysm

Juri Lieberg et al.

Summary: The study found that levels of certain amino acids and phosphatidylcholines were significantly lower in abdominal aortic aneurysm (AAA) patients compared to controls. However, there were no significant differences in metabolites distinguishing between patients with slow or fast growth of the AAA.

METABOLITES (2021)

Review Biochemistry & Molecular Biology

Essential Role of Nonessential Amino Acid Glutamine in Atherosclerotic Cardiovascular Disease

Jinna Chen et al.

DNA AND CELL BIOLOGY (2020)

Review Cardiac & Cardiovascular Systems

Polyamines and microbiota in bicuspid and tricuspid aortic valve aortopathy

Amalia Forte et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2019)

Article Cardiac & Cardiovascular Systems

Safety of Men With Small and Medium Abdominal Aortic Aneurysms Under Surveillance in the NAAASP

Clare Oliver-Williams et al.

CIRCULATION (2019)

Article Cardiac & Cardiovascular Systems

Activated platelets promote an osteogenic programme and the progression of calcific aortic valve stenosis

Rihab Bouchareb et al.

EUROPEAN HEART JOURNAL (2019)

Review Cardiac & Cardiovascular Systems

Mouse Models for Atherosclerosis Research-Which Is My Line?

Sara Oppi et al.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2019)

Article Cell Biology

Serum Biomarker Identification by Mass Spectrometry in Acute Aortic Dissection

Yong Ren et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

Article Urology & Nephrology

Dietary L-Lysine Prevents Arterial Calcification in Adenine-Induced Uremic Rats

Akihiro Shimomura et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)

Article Endocrinology & Metabolism

Acylcarnitines Reflecting or Inflicting Insulin Resistance?

Marieke G. Schooneman et al.

DIABETES (2013)

Review Biochemistry & Molecular Biology

Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation

Christoffel Petrus Stephanus Badenhorst et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2013)

Review Immunology

Role of arginase in vessel wall remodeling

William Durante

FRONTIERS IN IMMUNOLOGY (2013)

Article Surgery

Natural history of thoracic aortic aneurysms

Gregory A. Kuzmik et al.

JOURNAL OF VASCULAR SURGERY (2012)

Article Cardiac & Cardiovascular Systems

Serum secreted phospholipase A2 is associated with abdominal aortic aneurysm presence but not progression

Jonathan Golledge et al.

ATHEROSCLEROSIS (2011)

Article Biochemical Research Methods

pROC: an open-source package for R and S plus to analyze and compare ROC curves

Xavier Robin et al.

BMC BIOINFORMATICS (2011)

Article Surgery

Management of Abdominal Aortic Aneurysms Clinical Practice Guidelines of the European Society for Vascular Surgery

F. L. Moll et al.

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY (2011)

Article Cardiac & Cardiovascular Systems

ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice

Lisa A. Cassis et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)

Review Cardiac & Cardiovascular Systems

Pharmacological treatment of abdominal aortic aneurysm

Takashi Miyake et al.

CARDIOVASCULAR RESEARCH (2009)

Article Biochemistry & Molecular Biology

Corresponding increase in long-chain acyl-CoA and acylcarnitine after exercise in muscle from VLCAD mice

Frank ter Veld et al.

JOURNAL OF LIPID RESEARCH (2009)

Review Cell Biology

Angiotensin II and the development of insulin resistance: Implications for diabetes

J. Alberto Olivares-Reyes et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)

Review Hematology

Topological determinants and consequences of adventitial responses to arterial wall injury

Jean-Baptiste Michel et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)

Article Pharmacology & Pharmacy

L-carnitine prevents the progression of atherosclerotic lesions in hypercholesterolaemic rabbits

MM Sayed-Ahmed et al.

PHARMACOLOGICAL RESEARCH (2001)

Article Surgery

Murine aortic aneurysm produced by periarterial application of calcium chloride

AC Chiou et al.

JOURNAL OF SURGICAL RESEARCH (2001)