4.7 Review

Reprogramming Metabolism of Macrophages as a Target for Kidney Dysfunction Treatment in Autoimmune Diseases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Rheumatology

Clinical spectrum and therapeutic management of systemic lupus erythematosus-associated macrophage activation syndrome: a study of 20 Moroccan adult patients

Ammouri Wafa et al.

Summary: This study aimed to investigate the clinical and laboratory manifestations, triggers, treatment, and outcome of macrophage activation syndrome (MAS) complicating systemic lupus erythematosus (SLE). The study found that fever, splenomegaly, lymphadenopathy, profound cytopenia, hyperferritinemia, hypertriglyceridemia, high SLEDAI, and H-Score were associated with MAS. Early diagnosis and urgent therapeutic management improved the overall prognosis.

CLINICAL RHEUMATOLOGY (2022)

Article Rheumatology

CCR2-and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis

Takeshi Zoshima et al.

Summary: The study reveals that CCR2 and CCR5 regulate glomerular macrophage infiltration and contribute to the development of glomerular endocapillary hypercellularity in LN. CCR5 inhibition can be a specific therapy for endocapillary hypercellularity without inducing wire-loop lesions.

RHEUMATOLOGY (2022)

Article Nutrition & Dietetics

Weight Loss and Short-Chain Fatty Acids Reduce Systemic Inflammation in Monocytes and Adipose Tissue Macrophages from Obese Subjects

Shaun Eslick et al.

Summary: Weight loss and ex vivo short-chain fatty acid (SCFA) treatments were found to successfully attenuate systemic inflammation in obese individuals. These treatments not only reduced the production of inflammatory cytokines, but also altered the expression of certain genes.

NUTRIENTS (2022)

Review Pharmacology & Pharmacy

Targeting Regulatory T Cells for Therapy of Lupus Nephritis

Rajkumar Venkatadri et al.

Summary: Lupus glomerulonephritis is a complex autoimmune disease with limited treatment options. Treg-enhancement and indirect Treg-modulation strategies are being investigated.

FRONTIERS IN PHARMACOLOGY (2022)

Article Instruments & Instrumentation

Improving dexamethasone drug loading and efficacy in treating arthritis through a lipophilic prodrug entrapped into PLGA-PEG nanoparticles

Rosana Simon-Vazquez et al.

Summary: Encapsulation of dexamethasone palmitate into nanoparticles can enhance drug loading and reduce side effects, leading to improved efficacy in treating arthritis.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2022)

Article Medicine, General & Internal

Frequency of Renal Function Parameter Abnormalities in Patients with Psoriatic Arthritis and Rheumatoid Arthritis: Real-World Evidence from Clinical Practice

Fabiola Atzeni et al.

Summary: This study compared renal function parameters in patients with psoriatic arthritis (PsA) and rheumatoid arthritis (RA), finding similar prevalence of renal function abnormalities during treatment. Disease relapse may impact renal function in patients with PsA.

JOURNAL OF CLINICAL MEDICINE (2022)

Article Biochemistry & Molecular Biology

CRABP1-CaMKII-Agrn regulates the maintenance of neuromuscular junction in spinal motor neuron

Yu-Lung Lin et al.

Summary: This study identifies the role of cellular retinoic acid-binding protein 1 (CRABP1) in the formation and maintenance of the neuromuscular junction (NMJ) and highlights the regulatory role of CRABP1-CaMKII-Agrn signaling in NMJ. It also suggests a potential protective role of CRABP1 in MN diseases.

CELL DEATH AND DIFFERENTIATION (2022)

Article Immunology

Epithelial-mesenchymal Transition of Peritoneal Mesothelial Cells Is Enhanced by M2c Macrophage Polarization

Lifang Tian et al.

Summary: The study found that M2c macrophage polarization enhances EMT of PMCs, while M1 and M2a polarization also have an impact to some extent, but not as significant as M2c.

IMMUNOLOGICAL INVESTIGATIONS (2022)

Article Rheumatology

The relation of CD4(+)CD25+Foxp3+regulatory T cells concentration with disease activity and damage index in systemic lupus erythematosus

Mostafa Kamal et al.

Summary: This study assessed the percentage of circulating CD4(+)CD25(+)Foxp3(+) Treg cells in SLE patients and found a significant decrease compared to healthy controls. The percentage of Treg cells also showed negative correlations with disease activity and damage index.+
Article Immunology

The Contribution of Genetic Variation and Aberrant Methylation of Aryl Hydrocarbon Receptor Signaling Pathway Genes to Rheumatoid Arthritis

Tian-Ping Zhang et al.

Summary: The study found that polymorphisms in ARNT rs11204735, AHRR rs2292596, and rs2672725 were associated with susceptibility to rheumatoid arthritis (RA), while AHR gene polymorphisms showed no significant association with RA susceptibility. Additionally, altered methylation levels of AHR and AHRR genes were related to the risk of RA.

FRONTIERS IN IMMUNOLOGY (2022)

Review Biology

Environmental Factors and the Risk of Developing Type 1 Diabetes-Old Disease and New Data

Katarzyna Zorena et al.

Summary: Despite numerous studies, the risk factors of type 1 diabetes in children and adolescents remain a big challenge, highlighting the importance of research on environmental factors.

BIOLOGY-BASEL (2022)

Review Biochemistry & Molecular Biology

More than just protein building blocks: How amino acids and related metabolic pathways fuel macrophage polarization

Markus Kieler et al.

Summary: Macrophages play a crucial role in innate immune responses, regulating host inflammation and tissue homeostasis through different polarization states. Amino acid metabolism and related pathways are fundamentally involved in the intrinsic regulation of macrophage polarization and function.

FEBS JOURNAL (2021)

Review Immunology

Dynamic changes in macrophage metabolism modulate induction and suppression of Type I inflammatory responses

Haoming Luan et al.

Summary: Recent studies have shown that macrophage metabolism changes dynamically during microbial exposure, influencing a shift in inflammatory response. An initial increase in oxidative metabolism boosts the induction of inflammatory responses, while a shutdown of oxidative metabolism contributes to suppression of inflammatory responses.

CURRENT OPINION IN IMMUNOLOGY (2021)

Article Urology & Nephrology

The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Michael G. Shlipak et al.

Summary: Chronic kidney disease (CKD) is a significant global burden associated with higher morbidity and mortality, especially among individuals with lower socioeconomic status. Despite the availability of guidelines for evaluating and managing early CKD, there is still a lack of consensus on prioritizing early identification and intervention for CKD without incentives or quality measures.

KIDNEY INTERNATIONAL (2021)

Article Multidisciplinary Sciences

MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program

Yi Wang et al.

Summary: Despite extensive studies, the mechanisms underlying PF remain poorly understood. This study found altered MBD2 expression in macrophages in lungs from different types of PF patients and mice with PF, and Mbd2 deficiency protected against BLM-induced PF. Mbd2 selectively influenced TGF-β1 production and M2 macrophage program through Ship promoter binding in macrophages.

SCIENCE ADVANCES (2021)

Article Cell Biology

Mechanical stretch induces osteogenesis through the alternative activation of macrophages

Lili Dong et al.

Summary: This study reveals that macrophages stimulated with mechanical stretch under specific conditions can efficiently induce osteogenic differentiation of MSCs through a synergy mechanism between M2 polarization and YAP/BMP2 axis. Additionally, the mechanical stretch activates macrophages to produce anti-inflammatory cytokines, while also inducing YAP activation and downstream BMP2 expression to facilitate MSCs osteogenesis. These findings advance understanding of the complex influence among mechanical strain, macrophage inflammatory response, and MSC osteogenic differentiation, providing insights into the control system from mechanical signals to chemical response during bone repair and regeneration.

JOURNAL OF CELLULAR PHYSIOLOGY (2021)

Article Multidisciplinary Sciences

Salmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Lingyan Jiang et al.

Summary: S. Typhimurium infection induces upregulated glycolysis and decreased serine synthesis in host macrophages, leading to accumulation of glycolytic intermediates that promote bacterial replication and virulence.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

S-1-Propenylcysteine promotes IL-10-induced M2c macrophage polarization through prolonged activation of IL-10R/STAT3 signaling

Satomi Miki et al.

Summary: Overall, our study demonstrates that S1PC, a sulfur compound found in AGE, can enhance anti-inflammatory effects and promote M2c macrophage polarization, thus showing potential in improving atherosclerosis.

SCIENTIFIC REPORTS (2021)

Article Biochemistry & Molecular Biology

Lipopolysaccharide-Enhanced Responses against Aryl Hydrocarbon Receptor in FcgRIIb-Deficient Macrophages, a Profound Impact of an Environmental Toxin on a Lupus-Like Mouse Model

Kanyarat Udompornpitak et al.

Summary: The activation of Ahr may exacerbate the disease severity in FcgRIIb(-/-) mice, possibly through enhanced inflammatory responses. The deficiency of inhibitory-FcgRIIb in these mice may increase vulnerability to pro-inflammatory reactions.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Biochemistry & Molecular Biology

Two Faces of Macrophages: Training and Tolerance

Kiran Zubair et al.

Summary: Macrophages play crucial roles in host defense, wound healing, tissue regeneration, but also contribute to the development of various diseases such as cancers and autoimmune disorders. Studies have focused on understanding the molecular mechanisms of macrophage training and tolerance in inflammatory diseases.

BIOMEDICINES (2021)

Review Rheumatology

Renal dysfunction in systemic sclerosis beyond scleroderma renal crisis

George Iliopoulos et al.

Summary: Research has shown limited data about renal impairment in SSc beyond scleroderma renal crisis (SRC). However, studies indicate that renal dysfunction in SSc is not uncommon, with a significant percentage of patients having decreased glomerular filtration rate (GFR). The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula is suggested as a suitable tool for assessing renal function in SSc patients.

RHEUMATOLOGY INTERNATIONAL (2021)

Review Immunology

Macrophage Heterogeneity in Kidney Injury and Fibrosis

Yi Wen et al.

Summary: Kidney macrophages play crucial roles in the pathogenesis of kidney diseases, with diverse functions ranging from clearing pathogens to promoting fibrosis. Their origins and proliferation are key factors in the accumulation of macrophages after kidney injury. Understanding the mechanisms driving macrophage heterogeneity and function changes could help in the development of targeted therapies for kidney diseases.

FRONTIERS IN IMMUNOLOGY (2021)

Article Pharmacology & Pharmacy

Angiotensin involvement in kidney injury induced by rheumatoid arthritis in rat

Carla Patricia Carlos et al.

Summary: The study found that renal injury induced by AIA is associated with the stimulation of AT(1) in renal tissues, leading to glomerular inflammation and oxidative stress response, ultimately impairing renal function.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2021)

Article Neurosciences

The Long Non-coding RNA NEAT1/miR-224-5p/IL-33 Axis Modulates Macrophage M2a Polarization and A1 Astrocyte Activation

Dongliang Liu et al.

Summary: NEAT1 regulates macrophage M2a polarization by modulating miR-224-5p and IL-33, thus affecting the activation of A1 astrocytes.

MOLECULAR NEUROBIOLOGY (2021)

Review Physiology

The Role of Macrophages in Kidney Fibrosis

Xiaoling Wang et al.

Summary: Macrophages play complex roles in kidney diseases with both pro-inflammatory and anti-inflammatory phenotypes. While direct contribution to kidney fibrosis lacks clear evidence, they are essential in profibrotic signaling pathways. Further investigations are needed to explore their diverse functions in kidney fibrosis.

FRONTIERS IN PHYSIOLOGY (2021)

Article Immunology

M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration

Long Li et al.

Summary: The study found CD206-positive cells in degenerated intervertebral disc tissues, M2a macrophages promoted the expression of catabolism genes in NP cells but suppressed the expression of anabolism genes. These effects were eliminated by CHI3L1 knockdown. Exposure to recombinant CHI3L1 promoted an extracellular matrix metabolic imbalance in NP cells via the IL-13R alpha 2 receptor, along with activation of the ERK and JNK MAPK signaling pathways.

FRONTIERS IN IMMUNOLOGY (2021)

Article Physiology

Homoarginine ameliorates diabetic nephropathy independent of nitric oxide synthase-3

Michael D. Wetzel et al.

Summary: Homoarginine supplementation demonstrated kidney and heart protection in diabetic nephropathy models independently of NOS3, potentially mediated by improving mitochondrial function.

PHYSIOLOGICAL REPORTS (2021)

Article Biotechnology & Applied Microbiology

Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2

Harrison Specht et al.

Summary: The SCoPE2 technology was developed to improve the accuracy and throughput of single-cell proteomics through automated sample preparation, revealing the gradual differences in the proteome of macrophages during the enhancement of heterogeneity and allowing differentiation of cell states.

GENOME BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury

Lin-Li Lv et al.

CELL DEATH AND DIFFERENTIATION (2020)

Article Allergy

Resolvins: Emerging Players in Autoimmune and Inflammatory Diseases

Fereshte Abdolmaleki et al.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2020)

Article Cell & Tissue Engineering

Optimizing beta cell function through mesenchymal stromal cell-mediated mitochondria transfer

Chloe L. Rackham et al.

STEM CELLS (2020)

Review Cell Biology

Memory CD4(+) T Cells in Immunity and Autoimmune Diseases

Itay Raphael et al.

Review Immunology

Crosstalk Between Hypoxia and ER Stress Response: A Key Regulator of Macrophage Polarization

Paula Diaz-Bulnes et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Biochemistry & Molecular Biology

Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities

Lucas Opazo-Rios et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Immunology

Magnolol Attenuates Cisplatin-Induced Muscle Wasting by M2c Macrophage Activation

Chanju Lee et al.

FRONTIERS IN IMMUNOLOGY (2020)

Review Biochemistry & Molecular Biology

Macrophage Phenotype and Fibrosis in Diabetic Nephropathy

Priscila Calle et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Medicine, General & Internal

Lupus nephritis

Hans-Joachim Anders et al.

NATURE REVIEWS DISEASE PRIMERS (2020)

Article Multidisciplinary Sciences

Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins

Fengming Liu et al.

NATURE COMMUNICATIONS (2020)

Review Cell Biology

Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis

Qinghua Fang et al.

MEDIATORS OF INFLAMMATION (2020)

Review Urology & Nephrology

Targeting the progression of chronic kidney disease

Marta Ruiz-Ortega et al.

NATURE REVIEWS NEPHROLOGY (2020)

Editorial Material Medicine, General & Internal

Systemic Lupus Erythematosus

Marianthi Kiriakidou et al.

ANNALS OF INTERNAL MEDICINE (2020)

Review Immunology

Determinants of Resident Tissue Macrophage Identity and Function

Camille Bleriot et al.

IMMUNITY (2020)

Article Endocrinology & Metabolism

Attenuation of Diabetic Nephropathy in Diabetic Mice by Fasudil through Regulation of Macrophage Polarization

Fajiang Xie et al.

JOURNAL OF DIABETES RESEARCH (2020)

Review Medicine, General & Internal

Systemic lupus erythematosus 2020

Javier Narvaez

MEDICINA CLINICA (2020)

Article Multidisciplinary Sciences

Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis

Chenzhi Jing et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Identification of C3 as a therapeutic target for diabetic nephropathy by bioinformatics analysis

ShuMei Tang et al.

SCIENTIFIC REPORTS (2020)

Article Cell Biology

TAB1 regulates glycolysis and activation of macrophages in diabetic nephropathy

Hanxu Zeng et al.

INFLAMMATION RESEARCH (2020)

Article Urology & Nephrology

Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease

Bryan R. Conway et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

Article Multidisciplinary Sciences

Succination inactivates gasdermin D and blocks pyroptosis

Fiachra Humphries et al.

SCIENCE (2020)

Review Nutrition & Dietetics

Macrophage Polarization and Osteoporosis: A Review

Joseph Munoz et al.

NUTRIENTS (2020)

Review Physiology

Renal Involvement in Systemic Sclerosis: An Update

Magdalena Chrabaszcz et al.

KIDNEY & BLOOD PRESSURE RESEARCH (2020)

Review Biochemistry & Molecular Biology

Cellular and molecular mechanisms of kidney fibrosis

Sonja Djudjaj et al.

MOLECULAR ASPECTS OF MEDICINE (2019)

Article Biochemistry & Molecular Biology

Docosahexaenoic acid enhances M2 macrophage polarization via the p38 signaling pathway and autophagy

Aki Kawano et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Diabetic encephalopathy: beneficial effects of supplementation with fatty acids 3 and nordihydroguaiaretic acid in a spontaneous diabetes rat model

Gustavo Tomas Diaz-Gerevini et al.

LIPIDS IN HEALTH AND DISEASE (2019)

Review Urology & Nephrology

Macrophages: versatile players in renal inflammation and fibrosis

Patrick Ming-Kuen Tang et al.

NATURE REVIEWS NEPHROLOGY (2019)

Review Urology & Nephrology

M2 macrophages in kidney disease: biology, therapies, and perspectives

Titi Chen et al.

KIDNEY INTERNATIONAL (2019)

Article Biochemistry & Molecular Biology

Mesenchymal stem cells prevent the progression of diabetic nephropathy by improving mitochondrial function in tubular epithelial cells

Seung Eun Lee et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2019)

Article Urology & Nephrology

KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis

Yi Wen et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2019)

Review Immunology

Memory T Cells in Pregnancy

Tom E. C. Kieffer et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Immunology

The Metabolic Signature of Macrophage Responses

Antonella Viola et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Pathology

Diversity, Mechanisms, and Significance of Macrophage Plasticity

Massimo Locati et al.

Annual Review of Pathology-Mechanisms of Disease (2019)

Article Multidisciplinary Sciences

Macrophage phenotype and its relationship with renal function in human diabetic nephropathy

Xiaoliang Zhang et al.

PLOS ONE (2019)

Article Immunology

Exosomes Derived From M2b Macrophages Attenuate DSS-Induced Colitis

Ruibing Yang et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Immunology

The immunopathogenesis of fibrosis in systemic sclerosis

M. Brown et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2019)

Review Medicine, Research & Experimental

Histamine and diabetic nephropathy: an up-to-date overview

Alessandro Pini et al.

CLINICAL SCIENCE (2019)

Review Cell Biology

M2b macrophage polarization and its roles in diseases

Le-xun Wang et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2019)

Review Rheumatology

Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis

Zhu Chen et al.

NATURE REVIEWS RHEUMATOLOGY (2019)

Article Multidisciplinary Sciences

Trained immunity modulates inflammation-induced fibrosis

Mohamed Jeljeli et al.

NATURE COMMUNICATIONS (2019)

Article Physiology

l-Homoarginine supplementation prevents diabetic kidney damage

Michael D. Wetzel et al.

PHYSIOLOGICAL REPORTS (2019)

Review Endocrinology & Metabolism

Diabetic nephropathy: An update on pathogenesis and drug development

Vikram Rao A. L. B. Vasanth Rao et al.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2019)

Article Medicine, Research & Experimental

Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis

Divya Bhatia et al.

JCI INSIGHT (2019)

Article Urology & Nephrology

Wnt/beta-Catenin-Promoted Macrophage Alternative Activation Contributes to Kidney Fibrosis

Ye Feng et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)

Review Pharmacology & Pharmacy

M1/M2 Macrophages in Diabetic Nephropathy: Nrf2/HO-1 as Therapeutic Targets

Robert Clive Landis et al.

CURRENT PHARMACEUTICAL DESIGN (2018)

Review Immunology

Implications of macrophage polarization in autoimmunity

Samanta C. Funes et al.

IMMUNOLOGY (2018)

Review Biochemistry & Molecular Biology

Role of Human Macrophage Polarization in Inflammation during Infectious Diseases

Chiraz Atri et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Cell Biology

Macrophage plasticity, polarization, and function in health and disease

Abbas Shapouri-Moghaddam et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

Review Biochemistry & Molecular Biology

How Mitochondrial Metabolism Contributes to Macrophage Phenotype and Functions

Khaddouj Benmoussa et al.

JOURNAL OF MOLECULAR BIOLOGY (2018)

Article Obstetrics & Gynecology

The M2a macrophage subset may be critically involved in the fibrogenesis of endometriosis in mice

Jie Duan et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2018)

Article Multidisciplinary Sciences

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills et al.

NATURE (2018)

Article Urology & Nephrology

Update on Lupus Nephritis

Salem Almaani et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Article Endocrinology & Metabolism

Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy

Xin Wang et al.

DIABETES (2017)

Review Urology & Nephrology

Mitochondrial energetics in the kidney

Pallavi Bhargava et al.

NATURE REVIEWS NEPHROLOGY (2017)

Article Medicine, General & Internal

Chronic kidney disease

Paola Romagnani et al.

NATURE REVIEWS DISEASE PRIMERS (2017)

Article Endocrinology & Metabolism

Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset

Zachary J. Morse et al.

Frontiers in Endocrinology (2017)

Article Urology & Nephrology

Diabetic Kidney Disease Challenges, Progress, and Possibilities

Radica Z. Alicic et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Review Medicine, Research & Experimental

Diabetic nephropathy - is this an immune disorder?

Greg H. Tesch

CLINICAL SCIENCE (2017)

Review Immunology

The development and maintenance of resident macrophages

Elisa Gomez Perdiguero et al.

NATURE IMMUNOLOGY (2016)

Article Pharmacology & Pharmacy

Inhibition of SGLT2 alleviates diabetic nephropathy by suppressing high glucose-induced oxidative stress in type 1 diabetic mice

Takashi Hatanaka et al.

PHARMACOLOGY RESEARCH & PERSPECTIVES (2016)

Editorial Material Medicine, General & Internal

Chronic Kidney Disease

Paul Drawz et al.

ANNALS OF INTERNAL MEDICINE (2015)

Article Immunology

Macrophage depletion ameliorates nephritis induced by pathogenic antibodies

Samantha A. Chalmers et al.

JOURNAL OF AUTOIMMUNITY (2015)

Article Immunology

Contribution of metabolic reprogramming to macrophage plasticity and function

Karim C. EL Kasmi et al.

SEMINARS IN IMMUNOLOGY (2015)

Article Rheumatology

Chronic NSAID use and long-term decline of renal function in a prospective rheumatoid arthritis cohort study

Burkhard Moeller et al.

ANNALS OF THE RHEUMATIC DISEASES (2015)

Article Medicine, Research & Experimental

Different pathways of macrophage activation and polarization

Ulana Juhas et al.

POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ (2015)

Review Immunology

The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

Brigitta Stockinger et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)

Review Immunology

Diet, Metabolites, and Western-Lifestyle Inflammatory Diseases

Alison N. Thorburn et al.

IMMUNITY (2014)

Review Immunology

Tissue macrophage identity and self-renewal

Rebecca Gentek et al.

IMMUNOLOGICAL REVIEWS (2014)

Article Biochemistry & Molecular Biology

Metabolic Reprogramming of Macrophages GLUCOSE TRANSPORTER 1 (GLUT1)-MEDIATED GLUCOSE METABOLISM DRIVES A PROINFLAMMATORY PHENOTYPE

Alex J. Freemerman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

Diego Adhemar Jaitin et al.

SCIENCE (2014)

Review Biochemistry & Molecular Biology

Interferon regulatory factor 5 and autoimmune lupus

Wang-Dong Xu et al.

EXPERT REVIEWS IN MOLECULAR MEDICINE (2013)

Review Biochemistry & Molecular Biology

How Metabolism Generates Signals during Innate Immunity and Inflammation

Anne F. McGettrick et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Medicine, General & Internal

Chronic kidney disease: global dimension and perspectives

Vivekanand Jha et al.

LANCET (2013)

Article Multidisciplinary Sciences

High-Resolution Transcriptome of Human Macrophages

Marc Beyer et al.

PLOS ONE (2012)

Article Multidisciplinary Sciences

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

Johanneke Kleinnijenhuis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Urology & Nephrology

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

Sik Lee et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)

Article Nutrition & Dietetics

Extra-virgin olive oil-enriched diet modulates DSS-colitis-associated colon carcinogenesis in mice

S. Sanchez-Fidalgo et al.

CLINICAL NUTRITION (2010)

Article Biochemistry & Molecular Biology

Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys

Chongren Tang et al.

JOURNAL OF LIPID RESEARCH (2010)