期刊
INTERNATIONAL JOURNAL OF CARDIOLOGY
卷 366, 期 -, 页码 20-24出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ijcard.2022.07.021
关键词
Pregnancy; Congenital heart disease; Systemic right ventricle; Transposition of the great arteries; Congenitally corrected transposition of the great arteries
The increased trend of pregnancy among women with Congenital Heart Disease (CHD) has led to a growing demand for specialized care. Maternal CHD, especially in cases of Systemic Right Ventricle (SRV), may pose additional risks and challenges during pregnancy. Current literature lacks conclusive evidence on the feasibility and long-term effects of successful pregnancies in women with SRV.
In the recent years, the pregnancy trend among women with Congenital Heart Disease (CHD) has increased; this has leaded to a growing demand for specialized care both in mother and in children. Although pregnancy is often well tolerated, maternal CHD may affect in some cases a maladaptive hemodynamic response carrying additional risks of cardiovascular events like arrhythmias, heart failure and, in rare cases, death. The impaired uteroplacental perfusion due to maternal cardiac status may result in placental dysfunction, which may be associated with fetal growth restriction, preeclampsia, premature birth and perinatal morbidity. Systemic Right Ventricle (SRV) is one of the main conditions under which pregnancy is challenging. The sub-aortic position of morphological Right Ventricle (RV) is physiologically predisposed to fail at the adult age and may be potentially inadequate to support the hemodynamic stress of the pregnancy. Current literature about pregnancy in women with SRV consists of small retrospective series not providing conclusive evidence about the feasibility of a successful pregnancy outcomes. In addition, the long-term effects of pregnancy on SVR are not still adequately investigated and it remains unclear if maternal complications reported are due to pregnancy or to natural history of SVR. The aim of this paper is to offer a critical review of the knowledges at regard and to provide a practice update on the risk assessment and the pregnancy management in women with SRV in order to support the decision making and to optimize outcomes in these patients.
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