Characterization of resistance to newer antimicrobials among carbapenem-resistant Klebsiella pneumoniae in the post-acute-care setting

We assessed susceptibility patterns to newer antimicrobial agents among clinical carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates from patients in long-term acute-care hospitals (LTACHs) from 2014 to 2015. Meropenem-vaborbactam and imipenem-relebactam nonsusceptibility were observed among 9.9% and 9.1% of isolates, respectively. Nonsusceptibility to ceftazidime-avibactam (1.1%) and plazomicin (0.8%) were uncommon.

Automated summary

This study assessed the susceptibility patterns of clinical carbapenem-resistant Klebsiella pneumoniae isolates from patients in long-term acute-care hospitals to newer antimicrobial agents. The results showed high levels of nonsusceptibility to meropenem-vaborbactam and imipenem-relebactam, while nonsusceptibility to ceftazidime-avibactam and plazomicin was less common.