T-ZnO/AlGaN/GaN HEMT Uric Acid Sensor-Sensitivity Analysis and Effect of Surface Wettability for Improved Performance

In this work, a ZnO-Tetrapod (T-ZnO) bio-functionalized AlGaN/GaN HEMT based biosensor has been designed for detection of uric acid (UA) present in human serum. The proposed device is easy to fabricate and offers maximum drain current sensitivity of 92.5 mu A.mu M-1 and maximum threshold voltage sensitivity of 0.0229 mV.mu M-1 at UA concentration of 55 mu M. Sensitivity has been evaluated by normalizing the drain current, transconductance and channel conductance with respect to gate width. Maximum transconductance and channel conductance sensitivity obtained are 0.0151 mS/mu M and 0.0521 mS/mu M respectively at 55 mu M concentration. An analytical model has also been developed for drain current which shows good match with the simulated results and previously reported experimental data. Due to hydrophilic nature of AlGaN barrier layer the sensitivity of the sensor changes rapidly with change in surface wettability conditions thus the impact of variation of aluminum (Al) composition in AlGaN barrier layer and surface wettability on device performance has also been studied. The sensor exhibits a very low threshold voltage (V-th) hysteresis of 1.9 mV at VG-sweep = (- 8V, 0V) with a low response time of 260 mu s.

Automated summary

A bio-functionalized biosensor based on ZnO-Tetrapod and AlGaN/GaN HEMT has been designed for the detection of uric acid in human serum. The sensor offers high sensitivity, fast response time, and good match with previous experimental data, while its performance may be affected by surface wettability conditions and Al composition in the barrier layer.