期刊
GENES BRAIN AND BEHAVIOR
卷 21, 期 7, 页码 -出版社
WILEY
DOI: 10.1111/gbb.12826
关键词
anxiety; autism; fear conditioning; hippocampus; learning and memory; reward; ventral CA1
资金
- National Research Foundation [NRF-2012R1A3A1050385]
The hippocampus, especially the ventral CA1 (vCA1) region, plays a significant role in emotional behaviors. With the help of latest technologies, researchers are able to study the specific neural circuit and complex connectivity of the ventral hippocampus in-depth.
The hippocampus is one of the most widely investigated brain regions with its massive contributions to multiple behaviours. Especially, the hippocampus is subdivided into the dorsal and ventral parts playing distinct roles. In this review, we will focus on the ventral hippocampus, especially the ventral CA1 (vCA1), whose role is being actively discovered. vCA1 is well known to be associated with emotion-like behaviour, in both positive (reward) and negative (aversive) stimuli. How can this small region in volume mediate such variety of responses? This question will be answered with technologies up to date that have allowed us to study in-depth the specific neural circuit and to map the complex connectivity.
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