Efficacy and Safety of Salvia miltiorrhiza for Treating Chronic Kidney Diseases: A Systematic Review and Meta-Analysis

Article Environmental Sciences

Salvia miltiorrhiza polysaccharides alleviates florfenicol induced kidney injury in chicks via inhibiting oxidative stress and apoptosis

Xiao Wang et al.

Summary: This study investigated the alleviating effect of Salvia miltiorrhiza polysaccharides (SMPs) on florfenicol (FFC)-induced renal injury in chicks. The results showed that SMPs improved average weight gain and renal index, alleviated pathological changes in renal structure, and had antioxidant and anti-apoptotic effects on renal tissue. These findings suggest that SMPs have potential as a protective agent against FFC-induced nephrotoxicity.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022)

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Article Cell Biology

Salvianolate ameliorates oxidative stress and podocyte injury through modulation of NOX4 activity in db/db mice

Yiran Liang et al.

Summary: In this study, the effects of Salvianolate on diabetic nephropathy were investigated, showing that Salvianolate attenuated albuminuria, reduced podocyte loss, and restored podocyte loss in diabetic kidneys. Moreover, Salvianolate blocked HG-induced mitochondrial NOX4 derived superoxide generation in human podocytes, ameliorating podocyte apoptosis.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

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Review Medicine, General & Internal

PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

Matthew J. Page et al.

Summary: The methods and results of systematic reviews should be reported in sufficient detail to allow users to assess trustworthiness. PRISMA 2020 aims to improve the transparency and completeness of systematic review reporting, in hopes of guiding more accurate and transparent reporting.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Review Medicine, General & Internal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Article Integrative & Complementary Medicine