Adult-onset type 1 diabetes: A changing perspective

Type 1 diabetes most commonly presents in adulthood, contrary to the widely held view that it is a disease of childhood. Furthermore, a substantial proportion of cases of adult-onset type 1 diabetes does not require insulin therapy at clinical onset. Recent studies have emphasised the evidence that adult-onset type 1 diabetes is prevalent but often misclassified initially as type 2 diabetes (1, 2). In this review, we discuss that recent liter-ature, highlighting the similarities and differences between adult-onset and childhood-onset type 1 diabetes, exploring recent debates surrounding its epidemiology and genetics, as well as expanding on important issues of diagnostic criteria for individuals presenting with adult-onset diabetes and the subsequent management once identified as having an autoimmune basis. In addition, this review looks at the psychosocial challenges faced by T1D patients and their possible management.

Automated summary

Type 1 diabetes can occur in adults and may not require insulin therapy initially. This review compares adult-onset and childhood-onset type 1 diabetes, discusses their epidemiology, genetics, diagnostic criteria, and management, and also looks at the psychosocial challenges faced by T1D patients and how to manage them.