Pharmaceuticals in the Aquatic Environment: No Answers Yet to the Major Questions

The presence of pharmaceuticals in the environment, especially the aquatic environment, has received a lot of attention in the last 20 plus years. Despite that attention, the two most important questions regarding pharmaceuticals in the environment still cannot be answered. It is not possible to put the threat posed by pharmaceuticals into perspective with the many other threats (stressors) facing aquatic organisms, such as low flows due to over-abstraction of water, inhibited passage of migratory species due to dams and weirs, diseases, algal blooms causing low oxygen levels and releasing toxins, eutrophication, climate change, and so on. Nor is it possible to identify which pharmaceuticals are of concern and which are not. Not only can these key questions not be answered presently, they have received extremely little attention, despite being identified 10 years ago as the two most important questions to answer. That situation must change if resources and expertise are to be effectively used to protect the environment. Environ Toxicol Chem 2022;00:1-6. (c) 2022 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.

Automated summary

The presence of pharmaceuticals in the environment, especially in aquatic environments, has been a topic of concern for over 20 years. However, the two most important questions regarding pharmaceuticals in the environment - assessing their threat compared to other stressors and identifying which pharmaceuticals are of concern - remain unanswered. These key questions have received little attention despite being identified as crucial a decade ago. Addressing these questions is essential for effective environmental protection.