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Fullerenes for the treatment of cancer: an emerging tool

期刊

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
卷 29, 期 39, 页码 58607-58627

出版社

SPRINGER HEIDELBERG
DOI: 10.1007/s11356-022-21449-7

关键词

Nanotechnology; Biosensing; Cancer therapy; Photodynamic therapy; Biocompatibility; Biodegradability; Nanomedicine

资金

  1. Manipal Academy of Higher Education, Manipal

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This article discusses the potential applications of fullerenes in cancer treatment, emphasizing their unique physicochemical and photosensitizer properties.
Cancer is a most common cause of mortality globally. Available medicines possess severe side effects owing to their nonspecific targeting. Hence, there is a need of an alternative in the healthcare system that should have high efficacy with the least side effects, also having the ability to achieve site-specific targeting and be reproducible. This is possible with the help of fullerenes. Fullerenes are having the unique physicochemical and photosensitizer properties. This article discusses the synthesis, functionalization, mechanism, various properties, and applications of C60 fullerenes in the treatment of cancer. The review article also addresses the various factors influencing the activity of fullerenes including the environmental conditions, toxicity profile, and future prospective.

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