4.7 Article

Diesel exhaust particles distort lung epithelial progenitors and their fibroblast niche

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Respiratory System

Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD

Mahyar Aghapour et al.

Summary: Chronic exposure to environmental pollutants is a major contributor to the development and progression of obstructive airway diseases. Understanding the mechanisms underlying the development of such diseases upon exposure to inhaled pollutants will lead to novel insights into their prevention and treatment.

EUROPEAN RESPIRATORY REVIEW (2022)

Article Physiology

LL-37 and HMGB1 induce alveolar damage and reduce lung tissue regeneration via RAGE

Simon D. Pouwels et al.

Summary: Activation of RAGE by its ligands LL-37 and HMGB1 induces acute lung tissue damage and impedes alveolar epithelial repair, suggesting the therapeutic potential of RAGE inhibitors for lung tissue repair in emphysema.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2021)

Article Engineering, Environmental

Chemical and toxicological characterization of particulate emissions from diesel vehicles

Bei Wang et al.

Summary: This study provides a detailed characterization of diesel particulate matter emissions from vehicles, revealing that organic carbon dominates PM emissions and vehicles with diesel particulate filters have high OC/EC ratios. The study also shows significant correlations between specific compounds and toxicological markers, which can be valuable for policy makers in formulating emission control strategies.

JOURNAL OF HAZARDOUS MATERIALS (2021)

Article Critical Care Medicine

Air Pollution as a Risk Factor for Incident Chronic Obstructive Pulmonary Disease and Asthma A 15-Year Population-based Cohort Study

Saeha Shin et al.

Summary: The study found positive associations between PM2.5, NO2, O-3, and O-x with COPD, but did not find strong evidence linking these pollutants to adult-onset asthma. Additionally, each IQR increase in pollution exposure yielded excess cases of COPD, with most pollutant-COPD relationships exhibiting supralinear shapes.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2021)

Article Biochemistry & Molecular Biology

Drug metabolism in the lungs: opportunities for optimising inhaled medicines

Zachary Enlo-Scott et al.

Summary: This article provides a comprehensive overview of xenobiotic metabolizing enzymes in the lungs, their impact on inhaled medicines, and potential strategies for drug optimization. The review highlights the importance of considering lung metabolism in drug development and the various factors that can influence lung enzyme activity. New experimental technologies for studying lung metabolism are also discussed.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2021)

Article Environmental Sciences

Acute exposure to traffic-related air pollution alters antioxidant status in healthy adults

Kristen E. Cosselman et al.

ENVIRONMENTAL RESEARCH (2020)

Article Biochemistry & Molecular Biology

Dimethyl Fumarate Attenuates Lung Inflammation and Oxidative Stress Induced by Chronic Exposure to Diesel Exhaust Particles in Mice

Isabella Cattani-Cavalieri et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Physiology

TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation

John-Poul Ng-Blichfeldt et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2019)

Review Pharmacology & Pharmacy

Perspectives on Wnt Signal Pathway in the Pathogenesis and Therapeutics of Chronic Obstructive Pulmonary Disease

Jiao Qu et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2019)

Article Respiratory System

Air pollution, lung function and COPD: results from the population-based UK Biobank study

Dany Doiron et al.

EUROPEAN RESPIRATORY JOURNAL (2019)

Review Medicine, General & Internal

Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease

Alvar Agusti et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Cell Biology

Nrf2 attenuates inflammatory response in COPD/emphysema: Crosstalk with Wnt3a/-catenin and AMPK pathways

Wenhui Cui et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)

Article Multidisciplinary Sciences

Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells

Ahmad N. Nabhan et al.

SCIENCE (2018)

Article Respiratory System

Harmful impact of air pollution on severe acute exacerbation of chronic obstructive pulmonary disease: particulate matter is hazardous

Juwhan Choi et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2018)

Article Multidisciplinary Sciences

Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

William J. Zacharias et al.

NATURE (2018)

Article Pharmacology & Pharmacy

Expression of cytochrome P450 mRNAs in Type II alveolar cells from subjects with chronic obstructive pulmonary disease

Satoshi Kamata et al.

PHARMACOLOGY RESEARCH & PERSPECTIVES (2018)

Article Critical Care Medicine

Reduced Frizzled Receptor 4 Expression Prevents WNT/β-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease

Wioletta Skronska-Wasek et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)

Article Biochemistry & Molecular Biology

Toxic Effects of the Major Components of Diesel Exhaust in Human Alveolar Basal Epithelial Cells (A549)

Pavel Rossner et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Respiratory System

Chronic exposure of diesel exhaust particles induces alveolar enlargement in mice

Kelly Yoshizaki et al.

RESPIRATORY RESEARCH (2015)

Review Biochemistry & Molecular Biology

Intersection of AHR and Wnt Signaling in Development, Health, and Disease

Andrew J. Schneider et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Biochemistry & Molecular Biology

Conditional Overexpression of Receptors for Advanced Glycation End-Products in the Adult Murine Lung Causes Airspace Enlargement and Induces Inflammation

Megan P. Stogsdill et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)

Article Critical Care Medicine

Activation of the WNT/β-Catenin Pathway Attenuates Experimental Emphysema

Nikolaus Kneidinger et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Cardiac & Cardiovascular Systems

Advanced glycation end products and its receptor (RAGE) are increased in patients with COPD

Lian Wu et al.

RESPIRATORY MEDICINE (2011)

Article Cell Biology

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

Robin A. J. Smith et al.

MITOCHONDRIAL RESEARCH IN TRANSLATIONAL MEDICINE (2010)

Article Environmental Sciences

Exposure to ambient levels of particles emitted by traffic worsens emphysema in mice

Fernanda D. T. Q. S. Lopes et al.

ENVIRONMENTAL RESEARCH (2009)

Review Biochemistry & Molecular Biology

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

Truyen Nguyen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Public, Environmental & Occupational Health

Chronic obstructive pulmonary disease mortality in railroad workers

J. E. Hart et al.

OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2009)

Article Toxicology

Diesel exhaust particles

H.-E. Wichmann

INHALATION TOXICOLOGY (2007)

Review Biochemistry & Molecular Biology

Xenobiotic-metabolizing enzymes in human lung

Ji Y. Zhang et al.

CURRENT DRUG METABOLISM (2006)

Article Biotechnology & Applied Microbiology

Oxidative stress-induced DNA damage by particulate air pollution

L Risom et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2005)

Review Allergy

Biology of diesel exhaust effects on respiratory function

M Riedl et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)

Article Pharmacology & Pharmacy

Expression of cytochromes P450 1A1 and 1B1 in human lung from smokers, non-smokers, and ex-smokers

JH Kim et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)