Oscillation-coordinated, noise-resistant information distribution via the subiculum

The hippocampus processes information associated with spatial navigation. The subiculum receives input from the hippocampus CA1 and projects to various cortical and subcortical regions. Thus, the subiculum is uniquely positioned to distribute hippocampal information to a range of brain areas. Subicular neurons fire at higher rates than CA1 neurons and exhibit similarly or more accurately decodable representations of place, speed, and trajectory. These representations are more noise-resistant and advantageous for long-range information transfer. Subicular neurons selectively or uniformly distribute information to target areas, depending on the information type. Theta oscillations and sharp-wave ripples control information broadcasting in a pathway-specific manner. Thus, the subiculum routes accurately decodable, noise-resistant, navigation-associated information to downstream regions.

Automated summary

The hippocampus processes information related to spatial navigation and the subiculum plays a crucial role in distributing this information to different brain areas. Subicular neurons fire at higher rates and exhibit accurately decodable representations of place, speed, and trajectory, which are more resistant to noise and advantageous for long-range information transfer. The subiculum selectively or uniformly distributes information to target areas and theta oscillations and sharp-wave ripples control the broadcasting of information in a pathway-specific manner.