Relationship between epithelial organization and morphogen interpretation

Despite molecular noise and genetic differences between individuals, developmental outcomes are remarkably constant. Decades of research has focused on the underlying mechanisms that ensure this precision and robustness. Recent quantifications of chemical gradients and epithelial cell shapes provide novel insights into the basis of precise development. In this review, we argue that these two aspects may be linked in epithelial morphogenesis.

Automated summary

Researchers have investigated the underlying mechanisms that ensure the precision and robustness of developmental outcomes. Recent studies have provided new insights into the basis of precise development by quantifying chemical gradients and epithelial cell shapes.