4.7 Review

Targeting the gut to prevent and counteract metabolic disorders and pathologies during aging

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Nutrition & Dietetics

Probiotics for dementia: a systematic review and meta-analysis of randomized controlled trials

Jenifer F. Kruger et al.

Summary: Probiotic supplementation did not show significant benefits on cognitive function in individuals with dementia, but did improve certain metabolic markers. The current evidence is insufficient to support the clinical application of probiotics and synbiotics for individuals with dementia.

NUTRITION REVIEWS (2021)

Review Nutrition & Dietetics

Exploring the effects of phenolic compounds to reduce intestinal damage and improve the intestinal barrier integrity: A systematic review of in vivo animal studies

Berner Andree Sandoval-Ramirez et al.

Summary: Oral administration of phenolic compounds improves intestinal barrier integrity in animals by reducing inflammatory molecules, enhancing tight-junction protein expression, and boosting antioxidant activity.

CLINICAL NUTRITION (2021)

Review Nutrition & Dietetics

Targeting the Gut Microbiota to Improve Dietary Protein Efficacy to Mitigate Sarcopenia

Elena de Marco Castro et al.

Summary: Sarcopenia, characterized by decreased muscle mass and strength, is common in older adults due to anabolic resistance. The gut microbiota, which can change with age, may also play a role in sarcopenia development, potentially affecting muscle physiology by reducing inflammation and increasing protein digestibility. However, human data confirming this link is currently lacking.

FRONTIERS IN NUTRITION (2021)

Review Microbiology

Gut microbial metabolites as multi-kingdom intermediates

Kimberly A. Krautkramer et al.

Summary: The gut microbiota influences host physiology through the production of various metabolites. By studying microbial metabolites, researchers have identified potential microbial targets relevant for host health, despite the challenges of understanding host-microbiota interactions.

NATURE REVIEWS MICROBIOLOGY (2021)

Review Microbiology

Gut microbiota in human metabolic health and disease

Yong Fan et al.

Summary: The intestinal microbiota plays a significant role in human metabolic health, potentially contributing to the development of common metabolic disorders when dysregulated. Current research is shifting towards cause-and-effect studies and utilizing high-throughput human multi-omics data to identify potential molecular mechanisms behind these associations.

NATURE REVIEWS MICROBIOLOGY (2021)

Article Nutrition & Dietetics

A polyphenol-rich dietary pattern improves intestinal permeability, evaluated as serum zonulin levels, in older subjects: The MaPLE randomised controlled trial

Cristian Del Bo et al.

Summary: This study demonstrates that a polyphenol-rich diet can reduce serum zonulin levels, decrease blood pressure, and increase beneficial bacteria in the gut. These findings may open avenues for further research on dietary interventions for managing intestinal permeability, inflammation, and gut function in diverse populations.

CLINICAL NUTRITION (2021)

Article Gastroenterology & Hepatology

Gut microbiota-derived metabolites as central regulators in metabolic disorders

Allison Agus et al.

Summary: Metabolic disorders are closely linked to alterations in the composition and function of the gut microbiota. Specific classes of microbiota-derived metabolites play crucial roles in the pathogenesis of metabolic disorders.
Article Nutrition & Dietetics

California strawberry consumption increased the abundance of gut microorganisms related to lean body weight, health and longevity in healthy subjects

Zahra Ezzat-Zadeh et al.

Summary: The study showed that daily consumption of freeze-dried California strawberry powder can significantly change the intestinal microbiota and have effects on fecal cholesterol and bile acid microbial metabolites. Participants demonstrated good compliance after 4 weeks of SBP consumption, with alterations in gut microbiota abundance and some fecal metabolites observed.

NUTRITION RESEARCH (2021)

Review Biochemistry & Molecular Biology

Dietary Anti-Aging Polyphenols and Potential Mechanisms

Jing Luo et al.

Summary: Polyphenols have beneficial effects on health, anti-aging through various mechanisms, and may prevent aging-related diseases. Exploring the potential benefits of combinations of multiple polyphenols or polyphenol-rich foods is recommended.

ANTIOXIDANTS (2021)

Review Medicine, Research & Experimental

The complex role of adipokines in obesity, inflammation, and autoimmunity

Erin B. Taylor

Summary: The global obesity epidemic contributes to chronic low-grade inflammation and disease pathology through the dysregulation of adipokine production. Adipokines play a crucial role in immune response modulation, with implications in rheumatic and autoimmune diseases.

CLINICAL SCIENCE (2021)

Article Pharmacology & Pharmacy

Intersection of immunometabolism and immunosenescence during aging

Kyoo-A Lee et al.

Summary: Aging is closely linked to chronic or metabolic diseases, and improving metabolic and immune function in the elderly can enhance quality of life and reduce the risk of other diseases. Inflammaging and metabolic dysfunction are key factors in the aging process, with age-related changes seen in immune cells and metabolic tissues. Promising gerotherapeutics aim to target nutrient and energy sensing, inflammatory pathways, and senescence, offering potential to improve healthspan and treat age-related diseases.

CURRENT OPINION IN PHARMACOLOGY (2021)

Review Food Science & Technology

Role of dietary polyphenols on gut microbiota, their metabolites and health benefits

S. Mithul Aravind et al.

Summary: In the past two decades, there has been intensive research on the beneficial health roles of dietary polyphenols in preventing oxidative stress related chronic diseases. As our understanding of the role of gut microbiota advances, the need to examine the prebiotic role of dietary polyphenols has emerged. Further research should focus on the importance of human trials and the links of polyphenols-gut microbiota-nerve-brain to unlock the mechanisms behind the observed benefits of dietary polyphenols.

FOOD RESEARCH INTERNATIONAL (2021)

Review Cell Biology

Ageing of the gut microbiome: Potential influences on immune senescence and inflammageing

Jessica Conway et al.

Summary: With advancing age, changes in the gut microbiota driven by various factors can lead to immune response issues and inflammation, affecting healthy aging. Altering the gut microbiome composition may be a novel intervention strategy to reverse immune aging clock and support overall good health in old age.

AGEING RESEARCH REVIEWS (2021)

Review Clinical Neurology

Parkinson's disease and the gastrointestinal microbiome

Michal Lubomski et al.

JOURNAL OF NEUROLOGY (2020)

Review Agriculture, Multidisciplinary

Polyphenols and Intestinal Permeability: Rationale and Future Perspectives

Stefano Bernardi et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020)

Review Food Science & Technology

A critical review on grape polyphenols for neuroprotection: Strategies to enhance bioefficacy

Danyue Zhao et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2020)

Review Medicine, Research & Experimental

Short chain fatty acids and methylamines produced by gut microbiota as mediators and markers in the circulatory system

Maksymilian Onyszkiewicz et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2020)

Article Microbiology

Potential TMA-Producing Bacteria Are Ubiquitously Found in Mammalia

Silke Rath et al.

FRONTIERS IN MICROBIOLOGY (2020)

Review Endocrinology & Metabolism

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

Ygor Parladore Silva et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Review Medical Laboratory Technology

The gut microbiome and frailty

Damani A. Piggott et al.

TRANSLATIONAL RESEARCH (2020)

Article Geriatrics & Gerontology

Early Signs of Gut Microbiome Aging: Biomarkers of Inflammation, Metabolism, and Macromolecular Damage in Young Adulthood

Audrey Renson et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2020)

Article Medicine, General & Internal

Major Lipids, Apolipoproteins, and Alterations of Gut Microbiota

Kyung Eun Yun et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Review Microbiology

The Gut Microbiota and Unhealthy Aging: Disentangling Cause from Consequence

Erica N. DeJong et al.

CELL HOST & MICROBE (2020)

Article Multidisciplinary Sciences

Human Gut Microbiome Aging Clock Based on Taxonomic Profiling and Deep Learning

Fedor Galkin et al.

ISCIENCE (2020)

Review Gastroenterology & Hepatology

Exercise and intestinal permeability: another form of exercise-induced hormesis?

Bryant H. Keirns et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2020)

Review Cardiac & Cardiovascular Systems

Intestinal barrier dysfunction as a therapeutic target for cardiovascular disease

Caitlin Lewis et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2020)

Review Medicine, Research & Experimental

Gut microbiota-derived short-chain fatty acids and hypertension: Mechanism and treatment

Fan Yang et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Article Geriatrics & Gerontology

Probiotics ameliorate intestinal pathophysiology in a mouse model of Alzheimer’s disease

Harpreet Kaur et al.

NEUROBIOLOGY OF AGING (2020)

Article Biochemistry & Molecular Biology

Newly Explored Faecalibacterium Diversity Is Connected to Age, Lifestyle, Geography, and Disease

Francesca De Filippis et al.

CURRENT BIOLOGY (2020)

Article Nutrition & Dietetics

Associations between Diet, the Gut Microbiome, and Short-Chain Fatty Acid Production among Older Caribbean Latino Adults

Ana Maldonado-Contreras et al.

JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS (2020)

Article Biochemistry & Molecular Biology

LactobacillusStrains Alleviated Hyperlipidemia and Liver Steatosis in Aging Rats via Activation of AMPK

Lee-Ching Lew et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Geriatrics & Gerontology

Target Dysbiosis of Gut Microbes as a Future Therapeutic Manipulation in Alzheimer's Disease

Feiqi Zhu et al.

FRONTIERS IN AGING NEUROSCIENCE (2020)

Review Biochemistry & Molecular Biology

The Osteoporosis/Microbiota Linkage: The Role of miRNA

Massimo De Martinis et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Nutrition & Dietetics

The Gut Microbiome, Aging, and Longevity: A Systematic Review

Varsha D. Badal et al.

NUTRIENTS (2020)

Review Geriatrics & Gerontology

Is inflammageing influenced by the microbiota in the aged gut? A systematic review

Cabirou M. Shintouo et al.

EXPERIMENTAL GERONTOLOGY (2020)

Review Nutrition & Dietetics

Interactions between gut microbiota and skeletal muscle

Florence Gizard et al.

NUTRITION AND METABOLIC INSIGHTS (2020)

Review Nutrition & Dietetics

Effect of Berry Polyphenols on Glucose Metabolism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Theresa F. Rambaran et al.

CURRENT DEVELOPMENTS IN NUTRITION (2020)

Review Food Science & Technology

Prebiotic effect of dietary polyphenols: A systematic review

Aline Medeiros Alves-Santos et al.

JOURNAL OF FUNCTIONAL FOODS (2020)

Review Geriatrics & Gerontology

Can probiotics, prebiotics and synbiotics improve functional outcomes for older people: a systematic review

L. Coutts et al.

EUROPEAN GERIATRIC MEDICINE (2020)

Review Endocrinology & Metabolism

Short-chain fatty acids as potential regulators of skeletal muscle metabolism and function

James Frampton et al.

NATURE METABOLISM (2020)

Article Geriatrics & Gerontology

Sarcopenia: revised European consensus on definition and diagnosis

Alfonso J. Cruz-Jentoft et al.

AGE AND AGEING (2019)

Review Rheumatology

Sarcopenia

Anne Tournadre et al.

JOINT BONE SPINE (2019)

Article Medicine, Research & Experimental

Genistein enhances the secretion of glucagon-like peptide-1 (GLP-1) via downregulation of inflammatory responses

Kanwal Rehman et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Review Cardiac & Cardiovascular Systems

Intestinal Microbiota in Cardiovascular Health and Disease

W. H. Wilson Tang et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

Article Biochemistry & Molecular Biology

The Microbiome Mediates Environmental Effects on Aging

Brett B. Finlay et al.

BIOESSAYS (2019)

Review Biochemistry & Molecular Biology

Understanding Competition and Cooperation within the Mammalian Gut Microbiome

Katharine Z. Coyte et al.

CURRENT BIOLOGY (2019)

Review Medicine, General & Internal

Sarcopenia

Alfonso J. Cruz-Jentoft et al.

LANCET (2019)

Article Cell Biology

The gut microbiota influences skeletal muscle mass and function in mice

Shawon Lahiri et al.

SCIENCE TRANSLATIONAL MEDICINE (2019)

Review Nutrition & Dietetics

Gut Microbiome: Profound Implications for Diet and Disease

Ronald D. Hills et al.

NUTRIENTS (2019)

Article Genetics & Heredity

The Microbiome and Aging

Bianca Bana et al.

Annual Review of Genetics (2019)

Article Pharmacology & Pharmacy

Lactobacillus sp. improved microbiota and metabolite profiles of aging rats

Yan-Yan Hor et al.

PHARMACOLOGICAL RESEARCH (2019)

Review Immunology

Targeting the Gut Microbiota to Treat Cachexia

Laurence Genton et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2019)

Review Endocrinology & Metabolism

The intestinal microbiome and its relevance for functionality in older persons

Andrea Ticinesi et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2019)

Review Biochemistry & Molecular Biology

The Microbiota and Cancer Cachexia

Kelly M. Herremans et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Neurosciences

The Possibility of an Infectious Etiology of Alzheimer Disease

Ghulam M. Ashraf et al.

MOLECULAR NEUROBIOLOGY (2019)

Article Geriatrics & Gerontology

CAN A PREBIOTIC FORMULATION REDUCE FRAILTY LEVELS IN OLDER PEOPLE?

O. Theou et al.

JOURNAL OF FRAILTY & AGING (2019)

Review Cardiac & Cardiovascular Systems

Cardiovascular Risks Associated with Gender and Aging

Jennifer L. Rodgers et al.

JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2019)

Review Geriatrics & Gerontology

Exercise, the Gut Microbiome, and Frailty

Hyung Eun Shin et al.

ANNALS OF GERIATRIC MEDICINE AND RESEARCH (2019)

Article Nutrition & Dietetics

Prevalence and determinants of low protein intake in very old adults: insights from the Newcastle 85+Study

Nuno Mendonca et al.

EUROPEAN JOURNAL OF NUTRITION (2018)

Editorial Material Chemistry, Multidisciplinary

Extracellular vesicles as novel biomarkers and pharmaceutic targets of diseases

Yanfang Chen et al.

ACTA PHARMACOLOGICA SINICA (2018)

Review Geriatrics & Gerontology

Effectiveness of probiotics on the occurrence of infections in older people: systematic review and meta-analysis

Patrick Alexander Wachholz et al.

AGE AND AGEING (2018)

Article Medicine, Research & Experimental

Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure

Seungbum Kim et al.

CLINICAL SCIENCE (2018)

Review Biochemical Research Methods

Modeling metabolism of the human gut microbiome

Stefania Magnusdottir et al.

CURRENT OPINION IN BIOTECHNOLOGY (2018)

Review Cell Biology

Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia

Anna Picca et al.

MEDIATORS OF INFLAMMATION (2018)

Article Geriatrics & Gerontology

Serum Zonulin and Endotoxin Levels in Exceptional Longevity versus Precocious Myocardial Infarction

Pedro Carrera-Bastos et al.

AGING AND DISEASE (2018)

Review Physiology

Obesity, Fat Mass and Immune System: Role for Leptin

Vera Francisco et al.

FRONTIERS IN PHYSIOLOGY (2018)

Review Biochemistry & Molecular Biology

Fantastic voyage: the journey of intestinal microbiota-derived microvesicles through the body

Regis Stentz et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2018)

Review Biochemistry & Molecular Biology

Implication of gut microbiota metabolites in cardiovascular and metabolic diseases

Francois Brial et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Endocrinology & Metabolism

Inflammaging: a new immune-metabolic viewpoint for age-related diseases

Claudio Franceschi et al.

NATURE REVIEWS ENDOCRINOLOGY (2018)

Article Cell Biology

Dysbiosis signatures of gut microbiota in coronary artery disease

Qi Zhu et al.

PHYSIOLOGICAL GENOMICS (2018)

Review Multidisciplinary Sciences

The gut microbiota at the intersection of diet and human health

Christopher L. Gentile et al.

SCIENCE (2018)

Article Geriatrics & Gerontology

Probiotics and Prebiotics as a Therapeutic Strategy to Improve Memory in a Model of Middle-Aged Rats

Alejandra Romo-Araiza et al.

FRONTIERS IN AGING NEUROSCIENCE (2018)

Review Multidisciplinary Sciences

Recent developments in understanding the role of the gut microbiota in brain health and disease

Eoin Sherwin et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2018)

Review Medicine, General & Internal

Of Microbes and Minds: A Narrative Review on the Second Brain Aging

Riccardo Calvani et al.

FRONTIERS IN MEDICINE (2018)

Review Biochemistry & Molecular Biology

Microbiome-health interactions in older people

Paul W. O'Toole et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Biochemistry & Molecular Biology

Role of gut microbiota in aging-related health decline: insights from invertebrate models

Rebecca I. Clark et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Review Genetics & Heredity

A scheme for a flexible classification of dietary and health biomarkers

Qian Gao et al.

GENES AND NUTRITION (2017)

Review Medicine, General & Internal

Celiac Disease and Nonceliac Gluten Sensitivity A Review

Maureen M. Leonard et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Article Geriatrics & Gerontology

Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging

YanFei Qi et al.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2017)

Review Neurosciences

Interactions between the microbiota, immune and nervous systems in health and disease

Thomas C. Fung et al.

NATURE NEUROSCIENCE (2017)

Article Multidisciplinary Sciences

The gut microbiome in atherosclerotic cardiovascular disease

Zhuye Jie et al.

NATURE COMMUNICATIONS (2017)

Article Biotechnology & Applied Microbiology

Association Study of Gut Flora in Coronary Heart Disease through High-Throughput Sequencing

Li Cui et al.

BIOMED RESEARCH INTERNATIONAL (2017)

Review Microbiology

Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

Patrice D. Cani et al.

FRONTIERS IN MICROBIOLOGY (2017)

Review Genetics & Heredity

A scheme for a flexible classification of dietary and health biomarkers

Qian Gao et al.

GENES AND NUTRITION (2017)

Article Multidisciplinary Sciences

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

T. Harach et al.

SCIENTIFIC REPORTS (2017)

Article Multidisciplinary Sciences

Gut microbiome alterations in Alzheimer's disease

Nicholas M. Vogt et al.

SCIENTIFIC REPORTS (2017)

Review Microbiology

Systematically investigating the impact of medication on the gut microbiome

Lisa Maier et al.

CURRENT OPINION IN MICROBIOLOGY (2017)

Review Gastroenterology & Hepatology

Nutrition and the gut microbiome in the elderly

Nuria Salazar et al.

GUT MICROBES (2017)

Review Cell Biology

Gut microbiota: A player in aging and a target for anti-aging intervention

Alexander M. Vaiserman et al.

AGEING RESEARCH REVIEWS (2017)

Review Biochemistry & Molecular Biology

Gut-Brain Cross-Talk in Metabolic Control

Christoffer Clemmensen et al.

Review Medicine, General & Internal

Probiotics for the prevention of Clostridium-difficileassociated diarrhea in adults and children

Joshua Z. Goldenberg et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)

Article Gastroenterology & Hepatology

The gut microbiota and host health: a new clinical frontier

Julian R. Marchesi et al.

Article Biochemistry & Molecular Biology

Gut Microbiota and Extreme Longevity

Elena Biagi et al.

CURRENT BIOLOGY (2016)

Review Endocrinology & Metabolism

Interactions of gut microbiota with dietary polyphenols and consequences to human health

Francisco A. Tomas-Barberan et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2016)

Article Cardiac & Cardiovascular Systems

Trimethylamine N-oxide and prognosis in acute heart failure

Toru Suzuki et al.

Article Biochemistry & Molecular Biology

Effect of a Prebiotic Formulation on Frailty Syndrome: A Randomized, Double-Blind Clinical Trial

Cristina Buigues et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Review Medicine, General & Internal

The gut microbiota and metabolic disease: current understanding and future perspectives

T. Arora et al.

JOURNAL OF INTERNAL MEDICINE (2016)

Article Cardiac & Cardiovascular Systems

Plasma Trimethylamine N-Oxide, a Gut Microbe-Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden

Vichai Senthong et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Article Multidisciplinary Sciences

Human gut microbes impact host serum metabolome and insulin sensitivity

Helle Krogh Pedersen et al.

NATURE (2016)

Article Endocrinology & Metabolism

Gut microbiota promote bone growth via IGF1

Charlotte Ridler

Nature Reviews Endocrinology (2016)

Review Gastroenterology & Hepatology

Breakthroughs in the treatment and prevention of Clostridium difficile infection

Larry K. Kociolek et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2016)

Review Medicine, General & Internal

The Human Intestinal Microbiome in Health and Disease

Susan V. Lynch et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Multidisciplinary Sciences

Gut microbiota induce IGF-1 and promote bone formation and growth

Jing Yan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Genetics & Heredity

Signatures of early frailty in the gut microbiota

Matt Jackson et al.

GENOME MEDICINE (2016)

Review Microbiology

Gut Bifidobacteria Populations in Human Health and Aging

Silvia Arboleya et al.

FRONTIERS IN MICROBIOLOGY (2016)

Article Cardiac & Cardiovascular Systems

Trimethylamine N-Oxide and Mortality Risk in Patients With Peripheral Artery Disease

Vichai Senthong et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)

Review Endocrinology & Metabolism

Gut microbiota and immune crosstalk in metabolic disease

Remy Burcelin

MOLECULAR METABOLISM (2016)

Review Medicine, General & Internal

Dietary fibre for the primary prevention of cardiovascular disease

Louise Hartley et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2016)

Review Gastroenterology & Hepatology

Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism

Douglas J. Morrison et al.

GUT MICROBES (2016)

Review Biochemistry & Molecular Biology

Molecular Insight into Gut Microbiota and Rheumatoid Arthritis

Xiaohao Wu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Cell Biology

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

Saeed Shoaie et al.

CELL METABOLISM (2015)

Review Rheumatology

The intestinal microbiome in spondyloarthritis

Tejpal Gill et al.

CURRENT OPINION IN RHEUMATOLOGY (2015)

Article Medicine, General & Internal

Management of Diabetes in the Elderly

Nidhi Bansal et al.

MEDICAL CLINICS OF NORTH AMERICA (2015)

Article Neurosciences

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

Axel Montagne et al.

NEURON (2015)

Editorial Material Multidisciplinary Sciences

Gut microbiota and aging

Paul W. O'Toole et al.

SCIENCE (2015)

Article Biochemistry & Molecular Biology

Butyrate benefits the intestinal barrier

Annalisa M. VanHook

Science Signaling (2015)

Review Endocrinology & Metabolism

Effects of the gut microbiota on bone mass

Claes Ohlsson et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2015)

Review Medicine, Research & Experimental

Systems biology of host-microbe metabolomics

Almut Heinken et al.

WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2015)

Review Biotechnology & Applied Microbiology

A Survey of Modulation of Gut Microbiota by Dietary Polyphenols

Montserrat Duenas et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Article Biochemistry & Molecular Biology

Butyrate benefits the intestinal barrier

Annalisa M. VanHook

Science Signaling (2015)

Review Immunology

Interactions between Innate Immunity, Microbiota, and Probiotics

GianMarco Giorgetti et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2015)

Review Immunology

The composition of the gut microbiota throughout life, with an emphasis on early life

Juan Miguel Rodriguez et al.

MICROBIAL ECOLOGY IN HEALTH AND DISEASE (2015)

Review Gastroenterology & Hepatology

Metabolic Phenotyping and Systems Biology Approaches to Understanding Metabolic Syndrome and Fatty Liver Disease

Marc-Emmanuel Dumas et al.

GASTROENTEROLOGY (2014)

Article Cell Biology

Probiotic L. reuteri Treatment Prevents Bone Loss in a Menopausal Ovariectomized Mouse Model

Robert A. Britton et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2014)

Article Biochemistry & Molecular Biology

The Altered Tight Junctions: An Important Gateway of Bacterial Translocation in Cachexia Patients with Advanced Gastric Cancer

Yingjian Jiang et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2014)

Article Surgery

Outer membrane vesicles alter inflammation and coagulation mediators

Michael C. Soult et al.

JOURNAL OF SURGICAL RESEARCH (2014)

Review Neurosciences

BDNF-induced local protein synthesis and synaptic plasticity

Graciano Leal et al.

NEUROPHARMACOLOGY (2014)

Article Multidisciplinary Sciences

Probiotics Protect Mice from Ovariectomy-Induced Cortical Bone Loss

Claes Ohlsson et al.

PLOS ONE (2014)

Article Microbiology

Microbial shifts in the aging mouse gut

Morgan Gi Langille et al.

MICROBIOME (2014)

Review Endocrinology & Metabolism

Inflamm-ageing

Elisa Cevenini et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2013)

Review Biochemistry & Molecular Biology

Muscle wasting: The gut microbiota as a new therapeutic target?

Laure B. Bindels et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion

Hariom Yadav et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Gastroenterology & Hepatology

Cancer cachexia-pathophysiology and management

Hajime Suzuki et al.

JOURNAL OF GASTROENTEROLOGY (2013)

Article Nutrition & Dietetics

Habitual Dietary Intake Is Associated with Stool Microbiota Composition in Monozygotic Twins

Catarina D. Simoes et al.

JOURNAL OF NUTRITION (2013)

Article Multidisciplinary Sciences

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Yukihiro Furusawa et al.

NATURE (2013)

Article Multidisciplinary Sciences

Gut metagenome in European women with normal, impaired and diabetic glucose control

Fredrik H. Karlsson et al.

NATURE (2013)

Article Multidisciplinary Sciences

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

Patrick M. Smith et al.

SCIENCE (2013)

Article Nutrition & Dietetics

Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers

Maria Isabel Queipo-Ortuno et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2012)

Article Cardiac & Cardiovascular Systems

Studies on bacterial endotoxin and intestinal absorption function in patients with chronic heart failure

Anja Sandek et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2012)

Article Multidisciplinary Sciences

Gut microbiota composition correlates with diet and health in the elderly

Marcus J. Claesson et al.

NATURE (2012)

Article Multidisciplinary Sciences

A metagenome-wide association study of gut microbiota in type 2 diabetes

Junjie Qin et al.

NATURE (2012)

Review Neurosciences

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

John F. Cryan et al.

NATURE REVIEWS NEUROSCIENCE (2012)

Review Multidisciplinary Sciences

Host-Gut Microbiota Metabolic Interactions

Jeremy K. Nicholson et al.

SCIENCE (2012)

Article Multidisciplinary Sciences

Symptomatic atherosclerosis is associated with an altered gut metagenome

Fredrik H. Karlsson et al.

NATURE COMMUNICATIONS (2012)

Article Biochemistry & Molecular Biology

Gut barrier dysfunction in the ApcMin/+ mouse model of colon cancer cachexia

Melissa J. Puppa et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)

Article Nutrition & Dietetics

Diversity and metabolic impact of intestinal Lactobacillus species in healthy adults and the elderly

Jelena Stsepetova et al.

BRITISH JOURNAL OF NUTRITION (2011)

Article Geriatrics & Gerontology

The Frailty Syndrome: Definition and Natural History

Qian-Li Xue

CLINICS IN GERIATRIC MEDICINE (2011)

Article Microbiology

Kinetic modelling of lactate utilization and butyrate production by key human colonic bacterial species

Rafael Munoz-Tamayo et al.

FEMS MICROBIOLOGY ECOLOGY (2011)

Article Agriculture, Multidisciplinary

Six-Week Consumption of a Wild Blueberry Powder Drink Increases Bifidobacteria in the Human Gut

Stefano Vendrame et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2011)

Article Multidisciplinary Sciences

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Zeneng Wang et al.

NATURE (2011)

Article Multidisciplinary Sciences

Features, Causes and Consequences of Splanchnic Sequestration of Amino Acid in Old Rats

Marion Jourdan et al.

PLOS ONE (2011)

Article Multidisciplinary Sciences

Composition, variability, and temporal stability of the intestinal microbiota of the elderly

Marcus J. Claesson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Human oral, gut, and plaque microbiota in patients with atherosclerosis

Omry Koren et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Immunology

Probiotics and immunosenescence: cheese as a carrier

Fandi Ibrahim et al.

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY (2010)

Article Agriculture, Multidisciplinary

Novel Fibers Increase Bone Calcium Content and Strength beyond Efficiency of Large Intestine Fermentation

Connie M. Weaver et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats

Michele Balage et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2010)

Review Cell Biology

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

E. Maury et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)

Article Multidisciplinary Sciences

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

Nadja Larsen et al.

PLOS ONE (2010)

Article Gastroenterology & Hepatology

Constipation in old age

Paul Gallagher et al.

BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY (2009)

Article Endocrinology & Metabolism

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

Zhanguo Gao et al.

DIABETES (2009)

Article Nutrition & Dietetics

Bioavailability of α-linolenic acid from flaxseed diets as a function of the age of the subject

A. Patenaude et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2009)

Review Agriculture, Multidisciplinary

Interaction between Phenolics and Gut Microbiota: Role in Human Health

Maria V. Selma et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2009)

Article Multidisciplinary Sciences

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Kendle M. Maslowski et al.

NATURE (2009)

Article Cell Biology

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

Peter J. Turnbaugh et al.

SCIENCE TRANSLATIONAL MEDICINE (2009)

Article Biochemistry & Molecular Biology

An invitation to the marriage of metagenomics and metabolomics

Peter J. Turnbaugh et al.

Article Medicine, Research & Experimental

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

Shahla Abdollahi-Roodsaz et al.

JOURNAL OF CLINICAL INVESTIGATION (2008)

Article Nutrition & Dietetics

Intestinal Microbial Contribution to Metabolic Leucine Input in Adult Men

Tony Raj et al.

JOURNAL OF NUTRITION (2008)

Review Endocrinology & Metabolism

Bone in celiac disease

M. -L. Bianchi et al.

OSTEOPOROSIS INTERNATIONAL (2008)

Article Nutrition & Dietetics

Is the goal of mastication reached in young dentates, aged dentates and aged denture wearers?

Anne Mishellany-Dutour et al.

BRITISH JOURNAL OF NUTRITION (2008)

Article Endocrinology & Metabolism

The effect of vagal cooling on canine hepatic glucose metabolism in the presence of hyperglycemia of peripheral origin

Catherine A. DiCostanzo et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2007)

Article Biotechnology & Applied Microbiology

Intestinal bacteria and ageing

E. J. Woodmansey

JOURNAL OF APPLIED MICROBIOLOGY (2007)

Article Nutrition & Dietetics

Postprandial whole-body protein metabolism after a meat meal is influenced by chewing efficiency in elderly subjects

Didier Remond et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2007)

Article Multidisciplinary Sciences

Microbial ecology - Human gut microbes associated with obesity

Ruth E. Ley et al.

NATURE (2006)

Article Multidisciplinary Sciences

An obesity-associated gut microbiome with increased capacity for energy harvest

Peter J. Turnbaugh et al.

NATURE (2006)

Review Nutrition & Dietetics

Regulation of hepatic metabolism by enteral delivery of nutrients

D. Dardevet et al.

NUTRITION RESEARCH REVIEWS (2006)

Article Endocrinology & Metabolism

Role of the hepatic sympathetic nerves in the regulation of net hepatic glucose uptake and the mediation of the portal glucose signal

CA DiCostanzo et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)

Review Microbiology

Gut microorganisms, mammalian metabolism and personalized health care

JK Nicholson et al.

NATURE REVIEWS MICROBIOLOGY (2005)

Article Endocrinology & Metabolism

Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in conscious dogs

MC Moore et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)

Article Nutrition & Dietetics

Adipokines: inflammation and the pleiotropic role of white adipose tissue

P Trayhurn et al.

BRITISH JOURNAL OF NUTRITION (2004)

Review Hematology

Potential role of endotoxin as a proinflammatory mediator of atherosclerosis

LL Stoll et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)

Article Endocrinology & Metabolism

Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs

MC Moore et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Article Multidisciplinary Sciences

The gut microbiota as an environmental factor that regulates fat storage

F Bäckhed et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Nutrition & Dietetics

Pigs' gastrointestinal microflora provide them with essential amino acids

D Torrallardona et al.

JOURNAL OF NUTRITION (2003)

Review Endocrinology & Metabolism

Aging and insulin secretion

AM Chang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)

Article Nutrition & Dietetics

Influence of the protein digestion rate on protein turnover in young and elderly subjects

M Dangin et al.

JOURNAL OF NUTRITION (2002)

Article Dentistry, Oral Surgery & Medicine

The relationship among dental status, nutrient intake, and nutritional status in older people

A Sheiham et al.

JOURNAL OF DENTAL RESEARCH (2001)