☆ 4.7 Review

Overview-gold nanoparticles-based sensitive nanosensors in mycotoxins detection

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)

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Article Biochemical Research Methods

Key criteria for engineering mycotoxin binding aptamers via computational simulations: Aflatoxin B1 as a case study

Maryam Mousivand et al.

Summary: The study used computational techniques to improve the efficiency of screening high affinity aptamers for mycotoxins and conducted experimental affinity measurements. Research findings showed that aptamer F20 exhibited the best free binding energy and complex stability, primarily binding to AFB1 through precise shape complementarity and dynamic water intermediate interactions, with van der Waals contacts identified as the dominant energy component in all complexes.

BIOTECHNOLOGY JOURNAL (2022)

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Article Chemistry, Applied

Development of a label-free plasmonic gold nanoparticles aggregates sensor on the basis of charge neutralization for the detection of zearalenone

Keyu Xing et al.

Summary: A label-free, colorimetric, and fluorescence dual-channel sensing platform was developed for the detection of zearalenone in corn, allowing for quantitative detection as low as 0.89 µg kg-1 and visual detection as low as 2.5 µg kg-1. The formation of plasmonic gold nanoparticles aggregates based on charge neutralization by SYBR Green I eliminates instability in traditional gold nanoparticles colorimetric measurements, paving the way for accurate and label-free bioanalysis.

FOOD CHEMISTRY (2022)

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Article Food Science & Technology

Colorimetric immunoassay via smartphone based on Mn2+-Mediated aggregation of AuNPs for convenient detection of fumonisin B1

Yao Yu et al.

Summary: A colorimetric immunoassay based on the aggregation of gold nanoparticles was proposed for the detection of FB1, with a low detection limit, no cross-reaction with other mycotoxins, and potential application for food safety monitoring.

FOOD CONTROL (2022)

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Article Mycology

Camelization of a murine single-domain antibody against aflatoxin B1 and its antigen-binding analysis

Qian Pang et al.

Summary: In this study, a camelized, murine antibody against AFB(1) was prepared in vitro and used to develop an immunoassay for AFB(1). The camelized antibody showed significantly enhanced AFB(1)-binding interactions compared to the original murine antibody. This study provides effective strategies for in vitro preparation of camelized antibodies and offers a promising immunoreagent for AFB(1) detection.

MYCOTOXIN RESEARCH (2022)

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Article Chemistry, Applied

Ti3C2Tx MXenes loaded with Au nanoparticle dimers as a surface-enhanced Raman scattering aptasensor for AFB1 detection

Zhihui Wu et al.

Summary: A ratiometric surface-enhanced Raman scattering (SERS) aptasensor for AFB1 detection was developed utilizing BPE to trigger the assembly of AuNP dimers and the interaction between MXenes nanosheets and aptamer-modified AuNP dimers. The sensor showed promising results in detecting AFB1 with a limit of detection (LOD) of 0.6 pg.mL(-1) in standard solution.

FOOD CHEMISTRY (2022)

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Article Chemistry, Applied

A novel screening on the specific peptide by molecular simulation and development of the electrochemical immunosensor for aflatoxin B1 in grains

Bing Liu et al.

Summary: In this study, a library of specific peptides for AFB1 was constructed based on a specific antibody obtained from the PDB. A novel immunosensor without labeling was developed for the detection of AFB1 in cereals, showing high sensitivity and accuracy.

FOOD CHEMISTRY (2022)

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Article Food Science & Technology

A surface-enhanced Raman scattering aptasensor for ratiometric detection of aflatoxin B1 based on graphene oxide-Au@Ag core-shell nanoparticles complex

Peifang Chen et al.

Summary: A novel ratiometric surface-enhanced Raman scattering (SERS) aptasensor based on graphene oxide (GO) was constructed for reliable detection of Aflatoxin B1 (AFB1). The sensor achieved a low limit of detection (LOD) of 0.1 pg/mL and showed potential application prospects in the food detection field, with a good negative correlation (R2 = 0.992) and a quantifiable test range from 0.0001 ng/mL to 100 ng/mL.

FOOD CONTROL (2022)

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Article Chemistry, Analytical

A highly sensitive and reproducible multiplex mycotoxin SERS array based on AuNPs-loaded inverse opal silica photonic crystal microsphere

Saisai Jiao et al.

Summary: A highly sensitive and reproducible multiplex mycotoxin SERS array has been established based on gold nanoparticles (AuNPs)-loaded inverse opal silica photonic crystal microsphere (SIPCM). This method, utilizing the competition immunoassay principle and three different Raman nanotags on SIPCM, shows wide linear detection ranges and low limits of detection for ochratoxin A (OTA), fumonisin B-1 (FB1), and deoxynivalenol (DON), with recovery rates comparable to the classical ELISA method. The SERS-based method exhibits advantages over fluorescence label or enzyme catalytic chemiluminescence methods, and has great potential in rapidly screening multiplex mycotoxins in real samples.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

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Article Biophysics

Label-free photoelectrochemical immunosensor for aflatoxin B1 detection based on the Z-scheme heterojunction of g-C3N4/Au/WO3

Fubin Pei et al.

Summary: A label-free photoelectrochemical immunosensor using a Z-scheme heterojunction of gold nanoparticles loaded on graphitic carbon nitride sheet and tungsten trioxide sphere composite was fabricated for sensitive detection of Aflatoxin B1. The immunosensor displayed a linear concentration range from 1.0 pg mL(-1) to 100 ng mL(-1) with a low detection limit of 0.33 pg mL(-1) for AFB1. Good reproducibility, stability, and specificity provide a solid foundation for practical application.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Food Science & Technology

Development of electrochemical aptasensor based on gold nanoparticles and electrospun carbon nanofibers for the detection of aflatoxin M1 in milk

Hamid Reza Rahmani et al.

Summary: An electrochemical aptasensor was developed using ECNF mat for detecting AFM1 in milk samples, showing low detection limit, wide linear range, high sensitivity, stability, reproducibility, and results comparable to HPLC. The simple preparation procedure of the ss-HSDNA/AuNPs/ECNF mat electrode provides promising potential for AFM1 detection in milk samples.

JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION (2021)

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Article Chemistry, Analytical

Aptamer-Target-Gold Nanoparticle Conjugates for the Quantification of Fumonisin B1

Vicente Antonio Miron-Merida et al.

Summary: The study assessed the performance of two aptamers (40 and 96 nt) in the colorimetric quantification of FB1 through an aptamer-target incubation step followed by the addition of gold nanoparticles (AuNPs) and NaCl. While MgCl2 and Tris-HCl were crucial for aptamer 96 and 40 nt, respectively, the latter was not specific for FB1. Instead, the formation of Aptamer (96 nt)-FB1-AuNP conjugates in MgCl2 exhibited stability to NaCl-induced aggregation at increasing FB1 concentrations. The application of asymmetric flow field-flow fractionation (AF4) allowed for size separation and characterization with a reduction in the limit of detection from 0.002 mu g/mL to 56 fg/mL.

BIOSENSORS-BASEL (2021)

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Article Spectroscopy

An optical aptasensor for aflatoxin M1 detection based on target-induced protection of gold nanoparticles against salt-induced aggregation and silica nanoparticles

Seyed Hamid Jalalian et al.

Summary: Aflatoxins pose significant risks to human health and the economy. Developing a rapid, precise, and inexpensive detection method is crucial. The colorimetric aptasensor based on gold nanoparticles can detect AFM(1) with high sensitivity and has practical applications in milk samples.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2021)

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Article Chemistry, Analytical

No-wash point-of-care biosensing assay for rapid and sensitive detection of aflatoxin B1

Bing Li et al.

Summary: This study developed a disposable POC biosensing assay for sensitive detection of AFB1 using the RGB color detector software on a smartphone and the peroxidase-like activity of gold nanoparticles. The syringe filters were used for physical separation and washing-free detection, providing a convenient and efficient testing method. The biosensing assay showed a linear concentration range of 100 fg mL(-1) to 50 ng mL(-1) with a detection limit of 33 fg mL(-1), demonstrating excellent selectivity, storage stability, and reproducibility. Additionally, the innovation in detection and analysis technology offers a more flexible and convenient strategy for small molecule analysis.

TALANTA (2021)

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Article Biochemistry & Molecular Biology

Mycotoxins aptasensing: From molecular docking to electrochemical detection of deoxynivalenol

Hasret Subak et al.

Summary: This study presents a voltammetric aptasensor for detecting deoxynivalenol (DON) mycotoxin, with insights gained from a computational study on the molecular mechanisms of interaction. The competitive format approach was successful in achieving a detection limit of 3.2 ng.mL(-1) within a 1-hour detection time, showing promising results for potential applications in food safety.

BIOELECTROCHEMISTRY (2021)

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Article Biophysics

Imaging sensor array coupled with dual-signal amplification strategy for ultrasensitive chemiluminescence immunoassay of multiple mycotoxins

Chen Zong et al.

Summary: A novel CL immunosensor array combined with a dual-signal amplification strategy was developed for rapid and ultrasensitive detection of multiple mycotoxins in herbal medicine. By immobilizing different proteins on different sensing sites, joint detection of several mycotoxins was achieved.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Agriculture, Multidisciplinary

Enhanced Non-Toxic Immunodetection of Alternaria Mycotoxin Tenuazonic Acid Based on Ferritin-Displayed Anti-Idiotypic Nanobody-Nanoluciferase Multimers

Feng Wang et al.

Summary: An enhanced non-toxic immunoassay based on ferritin-displayed anti-idiotypic nanobody-nanoluciferase multimers was successfully developed for the detection of tenuazonic acid, showing significant improvements in sensitivity and selectivity. The study demonstrated the potential of this approach for the accurate analysis of trace toxic contaminants in food samples, offering a promising strategy for the production of multivalent anti-idiotypic nanobodies and non-toxic immunoassays.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

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Article Chemistry, Analytical

A novel colorimetric aptasensor for ultrasensitive detection of aflatoxin M1 based on the combination of CRISPR-Cas12a, rolling circle amplification and catalytic activity of gold nanoparticles

Khalil Abnous et al.

Summary: A highly sensitive colorimetric aptasensor was developed for the detection of AFM(1) using CRISPR-Cas12a, RCA, and AuNPs. The sensor showed high selectivity towards AFM(1) with a detection limit as low as 0.05 ng/L, and was able to sensitively identify AFM(1) in spiked milk samples.

ANALYTICA CHIMICA ACTA (2021)

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Article Chemistry, Applied

Reliable colorimetric aptasensor exploiting 72-Mers ssDNA and gold nanoprobes for highly sensitive detection of aflatoxin M1 in milk

Jamras Lerdsri et al.

Summary: The development of a label-free colorimetric aptasensor for rapid quantification of aflatoxin M1 (AFM1) has been accomplished based on localized surface plasmon resonance (LSPR) and aggregation of gold nanoparticles (AuNPs). The sensor has a detection limit of 0.002 ng mL-1, high analytical sensitivity, and practicality for real samples.

JOURNAL OF FOOD COMPOSITION AND ANALYSIS (2021)

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Article Chemistry, Analytical

Biosensor based on antifouling PEG/Gold nanoparticles composite for sensitive detection of aflatoxin M1 in milk

Maroua Hamami et al.

Summary: A new nanometric aptasensing platform was developed for detecting aflatoxin M1 in milk, showing good sensitivity, low LOD, and good metrological performances. The platform was applied to detect AFM1 in pasteurized cow milk with promising results.

MICROCHEMICAL JOURNAL (2021)

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Article Pharmacology & Pharmacy

Induction of anti-Zearalenone immune response with mimotopes identified from a phage display peptide library

Jingming Zhou et al.

Summary: The study successfully induced mice to produce specific antibodies against ZEN by screening six mimotopes, demonstrating the immunogenicity of these displayed peptides.

TOXICON (2021)

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Article Food Science & Technology

Gold Nanobeads with Enhanced Absorbance for Improved Sensitivity in Competitive Lateral Flow Immunoassays

Xirui Chen et al.

Summary: The study enhances the detection sensitivity of lateral flow immunoassay (LFIA) by synthesizing three different sizes of gold nanobeads (GNBs), with the 129 nm GNBs showing the best sensitivity for fumonisin B-1 (FB1) detection. The developed GNB-LFIA demonstrates improved performance compared to conventional LFIA based on 20-40 nm AuNPs.

FOODS (2021)

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Article Agriculture, Multidisciplinary

Natural occurrence of Alternaria mycotoxins in wheat and potential of reducing associated risks using magnolol

Dongmei Jiang et al.

Summary: The study analyzed wheat samples from Hebei Province, China for Alternaria mycotoxins (AOH, AME, and TeA) and found that most Alternaria strains produce multiple toxins, with TeA being the predominant mycotoxin. Magnolol showed antifungal and antimycotoxigenic activity against Alternaria, suggesting it could be developed as a natural fungicide for wheat.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2021)

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Article Biophysics

Dual-target electrochemical aptasensor based on co-reduced molybdenum disulfide and Au NPs (rMoS2-Au) for multiplex detection of mycotoxins

Zheng Han et al.

BIOSENSORS & BIOELECTRONICS (2020)

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Article Engineering, Environmental

Colorimetric aptasensor for ochratoxin A detection based on enzyme-induced gold nanoparticle aggregation

Yue He et al.

JOURNAL OF HAZARDOUS MATERIALS (2020)

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Article Chemistry, Applied

On-spot surface enhanced Raman scattering detection of Aflatoxin B1 in peanut extracts using gold nanobipyramids evenly trapped into the AAO nanoholes

Bingyong Lin et al.

FOOD CHEMISTRY (2020)

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Article Chemistry, Applied

Single-chain variable fragment antibody-based immunochromatographic strip for rapid detection of fumonisin B1 in maize samples

Wenjie Ren et al.

FOOD CHEMISTRY (2020)

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Article Food Science & Technology

One-step rapid detection of fumonisin B1, dexyonivalenol and zearalenone in grains

Silu Hou et al.

FOOD CONTROL (2020)

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Article Chemistry, Analytical

Flower-like gold nanoparticles-based immunochromatographic test strip for rapid simultaneous detection of fumonisin B1 and deoxynivalenol in Chinese traditional medicine

Xinyu Huang et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2020)

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Article Chemistry, Analytical

Simultaneous electrochemical determination of ochratoxin A and fumonisin B1 with an aptasensor based on the use of a Y-shaped DNA structure on gold nanorods

Min Wei et al.

MICROCHIMICA ACTA (2020)

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Article Chemistry, Analytical

Colorimetric aggregation assay based on array of gold and silver nanoparticles for simultaneous analysis of aflatoxins, ochratoxin and zearalenone by using chemometric analysis and paper based analytical devices

Azarmidokht Sheini

MICROCHIMICA ACTA (2020)

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Article Chemistry, Analytical

Nanomodified Screen-Printed Electrode for direct determination of Aflatoxin B1 in malted barley samples

Ava Gevaerd et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

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Article Chemistry, Analytical

Label-free colorimetric aptasensor for rapid detection of aflatoxin B1 by utilizing cationic perylene probe and localized surface plasmon resonance of gold nanoparticles

Jamras Lerdsri et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

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Article Food Science & Technology

Environmental-friendly gold nanoparticle immunochromatographic assay for ochratoxin A based on biosynthetic mimetic mycotoxin-conjugates

K-H You et al.

WORLD MYCOTOXIN JOURNAL (2020)

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Article Chemistry, Analytical

Surface-plasmon-coupled chemiluminescence amplification of silver nanoparticles modified immunosensor for high-throughput ultrasensitive detection of multiple mycotoxins

Fan Jiang et al.

ANALYTICA CHIMICA ACTA (2020)

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Article Chemistry, Analytical

Chemiluminescent Enzyme Immunoassay and Bioluminescent Enzyme Immunoassay for Tenuazonic Acid Mycotoxin by Exploitation of Nanobody and Nanobody-Nanoluciferase Fusion

Feng Wang et al.

ANALYTICAL CHEMISTRY (2020)

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Article Biophysics

A smartphone-based dual detection mode device integrated with two lateral flow immunoassays for multiplex mycotoxins in cereals

Zhiwei Liu et al.

BIOSENSORS & BIOELECTRONICS (2020)

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Article Chemistry, Applied

A self-assembled electrochemical immunosensor for ultra-sensitive detection of ochratoxin A in medicinal and edible malt

Chaonan Sun et al.

FOOD CHEMISTRY (2020)

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Article Chemistry, Applied

Broad-spectrum detection of zeranol and its analogues by a colloidal gold-based lateral flow immunochromatographic assay in milk

Mengqi Yin et al.

FOOD CHEMISTRY (2020)

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Article Chemistry, Applied

A colorimetric biosensor for simultaneous ochratoxin A and aflatoxins B1 detection in agricultural products

Weiran Zhu et al.

FOOD CHEMISTRY (2020)

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Article Chemistry, Applied

Multicolor colorimetric detection of ochratoxin A via structure-switching aptamer and enzyme-induced metallization of gold nanorods

Fengyu Tian et al.

FOOD CHEMISTRY (2020)

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Article Engineering, Environmental

Multiplex SERS-based lateral flow immunosensor for the detection of major mycotoxins in maize utilizing dual Raman labels and triple test lines

Wanjun Zhang et al.

JOURNAL OF HAZARDOUS MATERIALS (2020)

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Article Chemistry, Analytical

Dark field microscope-based single nanoparticle identification coupled with statistical analysis for ultrasensitive biotoxin detection in complex sample matrix

Shaohua Xu et al.

MICROCHIMICA ACTA (2020)

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Article Chemistry, Analytical

Engineered gold nanoparticles as multicolor labels for simultaneous multi- mycotoxin detection on the immunochromatographic test strip nanosensor

Yuhao Wu et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

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Article Chemistry, Applied

Highly sensitive phage-magnetic-chemiluminescent enzyme immunoassay for determination of zearalenone

Ruxia Liu et al.

FOOD CHEMISTRY (2020)

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Article Chemistry, Applied

Prediction, evaluation, confirmation, and elimination of matrix effects for lateral flow test strip based rapid and on-site detection of aflatoxin B1 in tea soups

Wei Chen et al.

FOOD CHEMISTRY (2020)

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Article Chemistry, Applied

Gold nanorods etching-based plasmonic immunoassay for qualitative and quantitative detection of aflatoxin M1 in milk

Bolong Fang et al.

FOOD CHEMISTRY (2020)

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Article Food Science & Technology

Quantum dot nanobead-based fluorescent immunochromatographic assay for simultaneous quantitative detection of fumonisin B1, dexyonivalenol, and zearalenone in grains

Silu Hou et al.

FOOD CONTROL (2020)

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Article Chemistry, Applied

Highly sensitive lateral flow test with indirect labelling for zearalenone in baby food

Anastasiya V. Bartosh et al.

FOOD AND AGRICULTURAL IMMUNOLOGY (2020)

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Article Chemistry, Multidisciplinary

Microfluidic paper device for rapid detection of aflatoxin B1 using an aptamer based colorimetric assay

Aruna Kasoju et al.

RSC ADVANCES (2020)

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Article Chemistry, Applied

Anti-idiotypic VHH mediated environmentally friendly immunoassay for citrinin without mycotoxin

Liang Xiong et al.

FOOD AND AGRICULTURAL IMMUNOLOGY (2020)

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Article Chemistry, Analytical

Ultrasensitive and green electrochemical immunosensor for mycotoxin ochratoxin A based on phage displayed mimotope peptide

Si-lu Hou et al.

TALANTA (2019)

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Article Biochemical Research Methods

Preparation of dummy molecularly imprinted polymers for extraction of Zearalenone in grain samples

Zhipeng Huang et al.

JOURNAL OF CHROMATOGRAPHY A (2019)

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Article Chemistry, Analytical

Phage displayed mimotope peptide-based immunosensor for green and ultrasensitive detection of mycotoxin deoxynivalenol

Jiaxiang Yan et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2019)

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Article Chemistry, Analytical

A novel nanobody and mimotope based immunoassay for rapid analysis of aflatoxin B1

Fengchun Zhao et al.

TALANTA (2019)

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Article Chemistry, Analytical

An electrochemical aptasensor for highly sensitive detection of zearalenone based on PEI-MoS2-MWCNTs nanocomposite for signal enhancement

Luyao Ma et al.

ANALYTICA CHIMICA ACTA (2019)

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Article Biochemical Research Methods

Development and comparison of mimotope-based immunoassays for the analysis of fumonisin B1

Riikka Peltomaa et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2019)

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Article Chemistry, Analytical

Colorimetric determination of fumonisin B1 based on the aggregation of cysteamine-functionalized gold nanoparticles induced by a product of its hydrolysis

Thaksinan Chotchuang et al.

MICROCHIMICA ACTA (2019)

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Article Biophysics

A novel sandwich aptasensor for detecting T-2 toxin based on rGO-TEPA-Au@Pt nanorods with a dual signal amplification strategy

Hangtian Zhong et al.

BIOSENSORS & BIOELECTRONICS (2019)

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Article Chemistry, Applied

Determination of Fumonisin B1 in maize using molecularly imprinted polymer nanoparticles-based assay

Hasim Munawar et al.

FOOD CHEMISTRY (2019)

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Article Chemistry, Multidisciplinary

Paper-Based Microfluidic Device (DON-Chip) for Rapid and Low-Cost Deoxynivalenol Quantification in Food, Feed, and Feed Ingredients

Qian Jiang et al.

ACS SENSORS (2019)

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Article Biotechnology & Applied Microbiology

Extracellular production of functional single-chain variable fragment against aflatoxin B1 using Escherichia coli

K. -I. Na et al.

LETTERS IN APPLIED MICROBIOLOGY (2019)

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Review Chemistry, Analytical

Emerging strategies to develop sensitive AuNP-based ICTS nanosensors

Yaofeng Zhou et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2019)

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Article Chemistry, Physical

Optimizing linear polymer affinity agent properties for surface-enhanced Raman scattering detection of aflatoxin B1

Victoria M. Szlag et al.

MOLECULAR SYSTEMS DESIGN & ENGINEERING (2019)

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Article Chemistry, Applied

Development of a noncompetitive idiometric nanobodies phage immumoassay for the determination of fumonisin B1

Mei Shu et al.

FOOD AND AGRICULTURAL IMMUNOLOGY (2019)

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Article Food Science & Technology

Specific Monoclonal Antibody-Based Enzyme Immunoassay for Sensitive and Reliable Detection of Alternaria Mycotoxin Iso-Tenuazonic Acid in Food Products

Zhi-Li Xiao et al.

FOOD ANALYTICAL METHODS (2018)

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Article Nanoscience & Nanotechnology

Novel Colorimetric Aptasensor for Zearalenone Detection Based on Nontarget-Induced Aptamer Walker, Gold Nanoparticles, and Exonuclease-Assisted Recycling Amplification

Seyed Mohammad Taghdisi et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Article Biophysics

Gold nanoparticle-enhanced multiplexed imaging surface plasmon resonance (iSPR) detection of Fusarium mycotoxins in wheat

Md Zakir Hossain et al.

BIOSENSORS & BIOELECTRONICS (2018)

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Article Biophysics

Multi-branched gold nanoflower-embedded iron porphyrin for colorimetric immunosensor

Yaofeng Zhou et al.

BIOSENSORS & BIOELECTRONICS (2018)

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Article Chemistry, Applied

A peptide/maltose-binding protein fusion protein used to replace the traditional antigen for immunological detection of deoxynivalenol in food and feed

Yang Xu et al.

FOOD CHEMISTRY (2018)

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Article Agriculture, Multidisciplinary

Aptamer-Based Lateral Flow Test Strip for Rapid Detection of Zearalenone in Corn Samples

Shijia Wu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

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Article Agriculture, Multidisciplinary

Enhancement and Analysis of Human Antiaflatoxin B1 (AFB1) scFv Antibody-Ligand Interaction Using Chain Shuffling

Kuntalee Rangnoi et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

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Article Agriculture, Multidisciplinary

An ultrasensitive chemiluminescence immunoassay for fumonisin B-1 detection in cereals based on gold-coated magnetic nanoparticles

Mingsha Jie et al.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2018)

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Article Chemistry, Analytical

Exonuclease-assisted multicolor aptasensor for visual detection of ochratoxin A based on G-quadruplex-hemin DNAzyme-mediated etching of gold nanorod

Xinhui Yu et al.

MICROCHIMICA ACTA (2018)

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Review Chemistry, Analytical

VHH Antibodies: Reagents for Mycotoxin Detection in Food Products

Jia Wang et al.

SENSORS (2018)

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Article Chemistry, Analytical

Plasmonic ELISA based on enzyme-assisted etching of Au nanorods for the highly sensitive detection of aflatoxin B1 in corn samples

Ying Xiong et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

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Article Chemistry, Analytical

Colorimetric ELISA for ochratoxin A detection based on the urease-induced metallization of gold nanoflowers

Ke Pei et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

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Article Chemistry, Analytical

A colorimetric immunoassay based on glucose oxidase-induced AuNP aggregation for the detection of fumonisin B-1

Xirui Chen et al.

TALANTA (2018)

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Review Food Science & Technology

Nanobody Technology for Mycotoxin Detection: Current Status and Prospects

Ting He et al.

TOXINS (2018)

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Article Chemistry, Analytical

Colorimetric zearalenone assay based on the use of an aptamer and of gold nanoparticles with peroxidase-like activity

Shumin Sun et al.

MICROCHIMICA ACTA (2018)

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Review Chemistry, Organic

Antibody Developments and Immunoassays for Mycotoxins

Qing-hua He et al.

CURRENT ORGANIC CHEMISTRY (2017)

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Article Chemistry, Analytical

Microarray-Based Immunoassay with Synthetic Mimotopes for the Detection of Fumonisin B1

Riikka Peltomaa et al.

ANALYTICAL CHEMISTRY (2017)

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Article Biochemical Research Methods

Screening and development of DNA aptamers as capture probes for colorimetric detection of patulin

Shijia Wu et al.

ANALYTICAL BIOCHEMISTRY (2016)

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Article Chemistry, Analytical

Phage displayed anti-idiotypic nanobody mediated immuno-PCR for sensitive and environmentally friendly detection of mycotoxin ochratoxin A

Yanwei Ji et al.

ANALYTICAL METHODS (2016)

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Article Biotechnology & Applied Microbiology

Production of a phage-displayed mouse ScFv antibody against fumonisin B1 and molecular docking analysis of their interactions

Zu-Quan Hu et al.

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING (2016)

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Article Chemistry, Applied

Affinity improvement by fine tuning of single-chain variable fragment against aflatoxin B1

Won-Ki Min et al.

FOOD CHEMISTRY (2016)

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Screening and Molecular Evolution of a Single Chain Variable Fragment Antibody (scFv) against Citreoviridin Toxin

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Article Chemistry, Analytical

Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection

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Anti-idiotypic VHH phage display-mediated immuno-PCR for ultrasensitive determination of mycotoxin zearalenone in cereals

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Article Chemistry, Analytical

Phage-free peptide ELISA for ochratoxin A detection based on biotinylated mimotope as a competing antigen

Xuqiang Zou et al.

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Article Microbiology

Immuno Affinity SELEX for Simple, Rapid, and Cost-Effective Aptamer Enrichment and Identification against Aflatoxin B1

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FRONTIERS IN MICROBIOLOGY (2016)

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Controlled growth of immunogold for amplified optical detection of aflatoxin B1

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ANALYST (2015)

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An affinity improved single-chain antibody from phage display of a library derived from monoclonal antibodies detects fumonisins by immunoassay

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ANALYTICA CHIMICA ACTA (2015)

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Article Chemistry, Analytical

Deoxynivalenol-mimic nanobody isolated from a naive phage display nanobody library and its application in immunoassay

Yu-Lou Qiu et al.

ANALYTICA CHIMICA ACTA (2015)

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Article Chemistry, Applied

Affinity maturation of single-chain variable fragment specific for aflatoxin B1 using yeast surface display

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FOOD CHEMISTRY (2015)

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Review Chemistry, Analytical

Anti-idiotypic nanobody: A strategy for development of sensitive and green immunoassay for Fumonisin B1

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TALANTA (2015)

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Article Agriculture, Multidisciplinary

Screening of Single-Stranded DNA (ssDNA) Aptamers against a Zearalenone Monoclonal Antibody and Development of a ssDNA-Based Enzyme-Linked Oligonucleotide Assay for Determination of Zearalenone in Corn

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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2015)

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Article Biotechnology & Applied Microbiology

Expression of VH-linker-VL orientation-dependent single-chain Fv antibody fragment derived from hybridoma 2E6 against aflatoxin B1 in Escherichia coli

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Characterization of Anti-Citrinin Specific ScFvs Selected from Non-Immunized Mouse Splenocytes by Eukaryotic Ribosome Display

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PLOS ONE (2015)

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Article Chemistry, Analytical

New Approach for Development of Sensitive and Environmentally Friendly Immunoassay for Mycotoxin Fumonisin B1 Based on Using Peptide-MBP Fusion Protein as Substitute for Coating Antigen

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ANALYTICAL CHEMISTRY (2014)

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Article Chemistry, Analytical

VHH Phage-Based Competitive Real-Time Immuno-Polymerase Chain Reaction for Ultrasensitive Detection of Ochratoxin A in Cereal

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ANALYTICAL CHEMISTRY (2014)

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Article Chemistry, Analytical

Nanobody-Based Enzyme Immunoassay for Aflatoxin in Agro-Products with High Tolerance to Cosolvent Methanol

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ANALYTICAL CHEMISTRY (2014)

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Selection, identification, and application of Aflatoxin B1 aptamer

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EUROPEAN FOOD RESEARCH AND TECHNOLOGY (2014)

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Article Food Science & Technology

An immunomagnetic-bead-based enzyme-linked immunosorbent assay for sensitive quantification of fumonisin B1

Yuan-Kai Wang et al.

FOOD CONTROL (2014)

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Article Agriculture, Multidisciplinary

Screening and Identification of DNA Aptamers against T-2 Toxin Assisted by Graphene Oxide

Xiujuan Chen et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)

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Article Agriculture, Multidisciplinary

Development of a single-chain variable fragment antibody-based enzyme-linked immunosorbent assay for determination of fumonisin B1 in corn samples

Long Zou et al.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2014)

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Article Food Science & Technology

Selection and Characterization of a Novel DNA Aptamer for Label-Free Fluorescence Biosensing of Ochratoxin A

Maureen McKeague et al.

TOXINS (2014)

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Article Biochemical Research Methods

Selection and identification of ssDNA aptamers recognizing zearalenone

Xiujuan Chen et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2013)

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Article Chemistry, Analytical

Ochratoxin A Mimotope from Second-Generation Peptide Library and Its Application in Immunoassay

Zhen-yun He et al.

ANALYTICAL CHEMISTRY (2013)

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Article Chemistry, Analytical

Gold nanoparticles enhanced chemiluminescence - a novel approach for sensitive determination of aflatoxin-B1

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ANALYTICAL METHODS (2013)

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Article Biophysics

Peptide binding to ochratoxin A mycotoxin: A new approach in conception of biosensors

I. Bazin et al.

BIOSENSORS & BIOELECTRONICS (2013)

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Article Food Science & Technology

Development of a rapid and simultaneous immunochromatographic assay for the determination of zearalenone and fumonisin B1 in corn, wheat and feedstuff samples

Yuan-Kai Wang et al.

FOOD CONTROL (2013)

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Article Agriculture, Multidisciplinary

Simultaneous Quantitative Determination of Multiple Mycotoxins in Cereal and Feedstuff Samples by a Suspension Array Immunoassay

Yuan-Kai Wang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

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Article Agriculture, Multidisciplinary

Application of Mimotope Peptides of Fumonisin B1 in Peptide ELISA

Xing Liu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

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Article Agriculture, Multidisciplinary

Novel Chemiluminescence immunoassay for the Determination of Zearalenone in Food Samples Using Gold Nanoparticles Labeled with Streptavidin-Horseradish Peroxidase

Yuan-Kai Wang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2013)

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Article Chemistry, Analytical

Highly sensitive electrochemical immunoassay for zearalenone in grain and grain-based food

Yuan-Kai Wang et al.

MICROCHIMICA ACTA (2013)

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Article Food Science & Technology

Global occurrence of mycotoxins in the food and feed chain: facts and figures

G. Schatzmayr et al.

WORLD MYCOTOXIN JOURNAL (2013)

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Article Chemistry, Applied

Production and characterization of a single chain variable fragment (scFv) against the mycotoxin deoxynivalenol

Chris M. Maragos et al.

FOOD AND AGRICULTURAL IMMUNOLOGY (2012)

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Article Biotechnology & Applied Microbiology

AN IMMUNOASSAY FOR DETERMINING AFLATOXIN B1 USING A RECOMBINANT PHAGE AS A NONTOXIC COATING CONJUGATE

Renrong Liu et al.

JOURNAL OF FOOD SAFETY (2012)

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Article Chemistry, Applied

Characterisation of monoclonal antibody against aflatoxin B1 produced in hybridoma 2C12 and its single-chain variable fragment expressed in recombinant Escherichia coli

Won-Ki Min et al.

FOOD CHEMISTRY (2011)

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Article Chemistry, Applied

Phage-displayed peptides that mimic zearalenone and its application in immunoassay

Qing-Hua He et al.

FOOD CHEMISTRY (2011)

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Article Chemistry, Multidisciplinary

A Powerful Approach for the Selection of 2-Aminopurine Substitution Sites to Investigate RNA Folding

Marie F. Souliere et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

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Article Biochemistry & Molecular Biology

One-Step Detection of Aflatoxin-B1 Using scFv-Alkaline Phosphatase-Fusion Selected from Human Phage Display Antibody Library

Kuntalee Rangnoi et al.

MOLECULAR BIOTECHNOLOGY (2011)

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Article Biochemistry & Molecular Biology

Screening and Initial Binding Assessment of Fumonisin B1 Aptamers

Maureen McKeague et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2010)

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Article Biophysics

Magnetic nanogold microspheres-based lateral-flow immunodipstick for rapid detection of aflatoxin B2 in food

D. Tang et al.

BIOSENSORS & BIOELECTRONICS (2009)

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Article Chemistry, Analytical

Use of itaconic acid-based polymers for solid-phase extraction of deoxynivalenol and application to pasta analysis

Michelangelo Pascale et al.

ANALYTICA CHIMICA ACTA (2008)

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Article Agriculture, Multidisciplinary

Determination of Ochratoxin A with a DNA Aptamer

Jorge A. Cruz-Aguado et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)

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Article Biochemistry & Molecular Biology

Cloning, expression, and characterization of a single-domain antibody fragment with affinity for 15-acetyl-deoxynivalenol

Patrick J. Doyle et al.

MOLECULAR IMMUNOLOGY (2008)

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Review Biochemical Research Methods

SELEX-A (r)evolutionary method to generate high-affinity nucleic acid ligands

Regina Stoltenburg et al.

BIOMOLECULAR ENGINEERING (2007)

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Article Food Science & Technology

An immunoassay for ochratoxin A without the mycotoxin

Renrong Liu et al.

FOOD CONTROL (2007)

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Article Agriculture, Multidisciplinary

Production of a single-chain variable fragment antibody against fumonisin B1

B Lauer et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)

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Article Biochemical Research Methods

Cloning, expression, and characterization of single-chain variable fragment antibody against mycotoxin deoxynivalenol in recombinant Escherichia coli

GH Choi et al.

PROTEIN EXPRESSION AND PURIFICATION (2004)

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Article Biochemical Research Methods

Selection and characterisation of recombinant single-chain antibodies to the hapten Aflatoxin-B1 from naive recombinant antibody libraries

A Moghaddam et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2001)

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Article Biotechnology & Applied Microbiology

Phage-displayed peptides that mimic aflatoxin B1 in serological reactivity

K Thirumala-Devi et al.

JOURNAL OF APPLIED MICROBIOLOGY (2001)

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Review Multidisciplinary Sciences

Biochemistry - Adaptive recognition by nucleic acid aptamers

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SCIENCE (2000)

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