期刊
JOURNAL OF CLINICAL VIROLOGY
卷 74, 期 -, 页码 45-49出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jcv.2015.11.027
关键词
Bocavirus; HBoV; Stool; Gastroenteritis; Virulence
类别
Human bocavirus (HBoV) is a parvovirus that was discovered only a decade ago and currently includes four genotypes. HBoV-1 is predominantly found in the respiratory tract, whereas HBoV-2, HBoV-3, and HBoV-4 are mainly detected in stool. HBoV-1 is known to be associated with respiratory tract infections. In stool, the prevalence of HBoV (1-4) is similar between patients with gastro-intestinal symptoms and healthy controls in most studies. Furthermore, often other viruses are concurrently present. Both findings suggest that HBoV in stool is an innocent bystander rather than a true pathogen. Nevertheless, several gaps in knowledge on the role of HBoV in stool remain to be addressed. All studies were performed in primarily immunocompetent patients. The role of HBoV in immunocompromised patients remains unknown. (C) 2015 Elsevier B.V. All rights reserved.
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