期刊
CLINICAL AND EXPERIMENTAL DERMATOLOGY
卷 47, 期 11, 页码 2043-2045出版社
WILEY
DOI: 10.1111/ced.15353
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类别
资金
- National Natural Science Foundation of China [8177120948]
This article reports a 3-year-old Chinese boy with severe Type III PRP who was successfully treated with secukinumab alone.
Pityriasis rubra pilaris (PRP) is a rare, scaly, keratotic inflammatory skin disease characterized by red scaly patches, keratosis papules, palmoplantar keratoderma and scaling of the scalp. In severe cases, ectropion of the eyelid may occur, and erythroderma may further develop. Recently, it has been reported that secukinumab, a monoclonal anti-interleukin-17A antibody, has certain efficacy in the treatment of PRP. Herein, we report a 3-year-old Chinese boy with severe Type III (classic juvenile) PRP who was successfully treated with secukinumab alone.
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