4.7 Article

Molecular markers in cancer

期刊

CLINICA CHIMICA ACTA
卷 532, 期 -, 页码 95-114

出版社

ELSEVIER
DOI: 10.1016/j.cca.2022.05.029

关键词

Biomarkers; cfDNA; Diagnosis; Cancer; Prognosis; CTCs

资金

  1. Govind Ballabh Pant Institute of Postgraduate Education and Medi-cal Research (GIPMER) , New Delhi [BT/INF/22/SP33063/2019]
  2. Department of Biotechnology Government of India

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Cancer is a common health issue worldwide, causing significant socioeconomic burden. Despite awareness campaigns, cancer cases continue to rise due to an aging population and a lack of early detection methods. As a result, researchers have focused on non-traditional approaches such as novel imaging techniques and liquid biopsy, as well as identifying biomarkers for diagnostic, prognostic, and therapeutic purposes.
Cancer remains a common health issue having significant socioeconomic burden worldwide. Despite the awareness campaigns, cancer cases continue to increase due to an aging population and lack of early detection biomarkers. Accordingly, much research has focused on non-traditional approaches which include novel imaging modalities and liquid biopsy. In addition, a considerable number of biomacromolecules as well as other biomarkers have been identified to further explore their potential use as diagnostic, prognostic and therapeutic tools. In this review, we provide an update on these new findings and explore their clinical application in cancer.

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