4.7 Article

Targeting PDE4B (Phosphodiesterase-4 Subtype B) for Cardioprotection in Acute Myocardial Infarction via Neutrophils and Microcirculation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Cardiac & Cardiovascular Systems

A fresh look at coronary microembolization

Petra Kleinbongard et al.

Summary: This article discusses the impact of coronary microembolization on myocardial infarction, pointing out the damage to the cardiovascular system caused by mechanical stress and inflammatory instability's release of particulate debris and soluble substances, as well as the importance of prevention and treatment in clinical trials.

NATURE REVIEWS CARDIOLOGY (2022)

Review Cardiac & Cardiovascular Systems

Targeting cardiovascular inflammation: next steps in clinical translation

Patrick R. Lawler et al.

Summary: Systemic vascular inflammation plays crucial roles in the progression and destabilization of ASCVD, requiring more individualized approaches for successful clinical translation. High-sensitivity C-reactive protein may serve as a clinical measure of inflammation.

EUROPEAN HEART JOURNAL (2021)

Article Cardiac & Cardiovascular Systems

Inflammation, Infection and Venous Thromboembolism

Meaghan E. Colling et al.

Summary: The association between inflammation, infection, and venous thrombosis is crucial and can lead to pathological thrombosis. Cells like neutrophils, monocytes, and platelets play essential roles in host defense and thrombus formation. Understanding these mechanisms has advanced knowledge in human physiology and pathophysiology, offering new therapeutic targets for the treatment of thrombosis.

CIRCULATION RESEARCH (2021)

Review Cardiac & Cardiovascular Systems

Myocardial ischaemia-reperfusion injury and cardioprotection in perspective

Gerd Heusch

NATURE REVIEWS CARDIOLOGY (2020)

Article Multidisciplinary Sciences

Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome

Ramadan A. Ali et al.

NATURE COMMUNICATIONS (2019)

Review Cardiac & Cardiovascular Systems

Coronary microvascular obstruction: the new frontier in cardioprotection

Gerd Heusch

BASIC RESEARCH IN CARDIOLOGY (2019)

Review Immunology

Understanding Infection-Induced Thrombosis: Lessons Learned From Animal Models

Nonantzin Beristain-Covarrubias et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Cardiac & Cardiovascular Systems

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury JACC Review Topic of the Week

Sean M. Davidson et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

Review Cardiac & Cardiovascular Systems

The NLRP3 inflammasome in acute myocardial infarction

Stefano Toldo et al.

NATURE REVIEWS CARDIOLOGY (2018)

Review Medicine, General & Internal

Acute myocardial infarction

Grant W. Reed et al.

LANCET (2017)

Article Biochemistry & Molecular Biology

Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria

Florian Gaertner et al.

Article Cardiac & Cardiovascular Systems

Relationship Between Infarct Size and Outcomes Following Primary PCI Patient-Level Analysis From 10 Randomized Trials

Gregg W. Stone et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Review Hematology

Thrombosis: tangled up in NETs

Kimberly Martinod et al.

Article Critical Care Medicine

Cardiovascular Safety in Patients Receiving Roflumilast for the Treatment of COPD

William B. White et al.

Article Multidisciplinary Sciences

Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD

Kensei Komatsu et al.

NATURE COMMUNICATIONS (2013)

Review Pharmacology & Pharmacy

PDE4: A Novel Target in the Treatment of Chronic Obstructive Pulmonary Disease

J. M. Michalski et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)

Review Medicine, General & Internal

Mechanisms of disease: Myocardial reperfusion injury

Derek M. Yellon et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Review Pharmacology & Pharmacy

Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use

Andrew T. Bender et al.

PHARMACOLOGICAL REVIEWS (2006)

Review Cardiac & Cardiovascular Systems

Involvement of neutrophils in the pathogenesis of lethal myocardial reperfusion injury

J Vinten-Johansen

CARDIOVASCULAR RESEARCH (2004)

Article Multidisciplinary Sciences

Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-α responses

SLC Jin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Chemistry, Medicinal

The synthesis and biological evaluation of a novel series of phthalazine PDE4 inhibitors I

M Napoletano et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)