相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cleavable and tunable cysteine-specific arylation modification with aryl thioethers
Jian Li et al.
CHEMICAL SCIENCE (2021)
Revisiting signal transducer and activator of transcription 3 (STAT3) as an anticancer target and its inhibitor discovery: Where are we and where should we go?
Qiuyao Huang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
The application of differential scanning fluorimetry in exploring bisubstrate binding to protein arginine N-methyltransferase 1
Jennifer Brown et al.
METHODS (2020)
Perspective on CETSA Literature: Toward More Quantitative Data Interpretation
Brinton Seashore-Ludlow et al.
SLAS DISCOVERY (2020)
Revisiting the development of small molecular inhibitors that directly target the signal transducer and activator of transcription 3 (STAT3) domains
Po-Chang Shih
LIFE SCIENCES (2020)
Validating Signal Transducer and Activator of Transcription (STAT) Protein-Inhibitor Interactions Using Biochemical and Cellular Thermal Shift Assays
Sanaz Attarha et al.
ACS CHEMICAL BIOLOGY (2020)
Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death
S. Busker et al.
SCIENCE ADVANCES (2020)
N-Acetyl cysteine prevents activities of STAT3 inhibitors, Stattic and BP-1-102 independently of its antioxidant properties
Yuki Uchihara et al.
PHARMACOLOGICAL REPORTS (2019)
Very low intensity ultrasounds as a new strategy to improve selective delivery of nanoparticles-complexes in cancer cells
Rossella Loria et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
STAT3 differential scanning fluorimetry and differential scanning light scattering assays: Addressing a missing link in the characterization of STAT3 inhibitor interactions
Matthieu Desroses et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2018)
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
Daniel E. Johnson et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Brent D. G. Page et al.
NATURE COMMUNICATIONS (2018)
Quantitative Interpretation of Intracellular Drug Binding and Kinetics Using the Cellular Thermal Shift Assay
Brinton Seashore-Ludlow et al.
BIOCHEMISTRY (2018)
Regulation of type I interferon signaling in immunity and inflammation: A comprehensive review
Kun Chen et al.
JOURNAL OF AUTOIMMUNITY (2017)
Identification of novel small molecules that inhibit STAT3-dependent transcription and function
Iryna Kolosenko et al.
PLOS ONE (2017)
Strategies and Approaches of Targeting STAT3 for Cancer Treatment
Stefanie L. Furtek et al.
ACS CHEMICAL BIOLOGY (2016)
Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities
Ahmed M. Ali et al.
CHEMMEDCHEM (2016)
Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent
Daniel P. Ball et al.
ONCOTARGET (2016)
An aryl-thioether substituted nitrobenzothiadiazole probe for the selective detection of cysteine and homocysteine
Dayoung Lee et al.
CHEMICAL COMMUNICATIONS (2015)
LLL12, a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy
Mingxin Zuo et al.
ONCOTARGET (2015)
Impacts of wind stilling on solar radiation variability in China
Changgui Lin et al.
SCIENTIFIC REPORTS (2015)
Investigation of the protein alkylation sites of the STAT3:STAT3 inhibitor Stattic by mass spectrometry
Sibylle Heidelberger et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Recent developments in the use of differential scanning fluorometry in protein and small molecule discovery and characterization
Anton Simeonov
EXPERT OPINION ON DRUG DISCOVERY (2013)
Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay
Daniel Martinez Molina et al.
SCIENCE (2013)
Targeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma
Makoto Adachi et al.
ORAL ONCOLOGY (2012)
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
Xiaolei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding
Yunhua Shi et al.
PROTEIN SCIENCE (2012)
STAT3 SIGNALING: Anticancer Strategies and Challenges
Paul A. Johnston et al.
MOLECULAR INTERVENTIONS (2011)
Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein
Steven Fletcher et al.
BIOCHEMISTRY AND CELL BIOLOGY (2009)
Detergent binding explains anomalous SDS-PAGE migration of membrane proteins
Arianna Rath et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease
Julia Dambacher et al.
GUT (2007)
STAT3 as a central mediator of neoplastic cellular transformation
David A. Frank
CANCER LETTERS (2007)
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity
Khandaker Siddiquee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Evaluation of potential Stat3-regulated genes in human breast cancer
FC Hsieh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Activation of the STAT1 pathway in rheumatoid arthritis
PV Kasperkovitz et al.
ANNALS OF THE RHEUMATIC DISEASES (2004)
A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3
J Schust et al.
ANALYTICAL BIOCHEMISTRY (2004)
Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease
S Schreiber et al.
GUT (2002)
STATs: Transcriptional control and biological impact
DE Levy et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Complex roles of Stat1 in regulating gene expression
CV Ramana et al.
ONCOGENE (2000)
Roles of STAT3 defined by tissue-specific gene targeting
S Akira
ONCOGENE (2000)