Synthesis, molecular features and biological activities of modified plant polysaccharides

Plant polysaccharides represent a natural source material characterized by high ubiquity, abundance and biological activities that can be utilised as organic matter in numerous manufacturing processes including pharmaceutical. The goal-oriented modification of polysaccharides by chemical reactions brings about a substantial refinement in their molecular features and biological activity. An improved understanding of the intrinsic molecular features of plant polysaccharides, as well as the structure-activity relationship eventually caused by chemical alterations, may be fundamental for the development of technologies supporting their biomedical oriented exploitation. Herein, we attempt to provide a broader view on these topics and to illustrate methodologies of chemical modification. These are intended to enhance the functionality of plant polysaccharides, such as their modification-induced biological activities, finally making the products available for translational purposes.

Automated summary

Plant polysaccharides are a natural material with high potential for various applications. Chemical modification can improve their molecular features and biological activity, supporting their biomedical development. This article aims to provide a broader perspective and introduce methodologies for enhancing the functionality of plant polysaccharides.