相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Clinical characteristics and germline mutation spectrum of RB1 in Chinese patients with retinoblastoma: A dual-center study of 145 patients
Peiwei Chai et al.
EXPERIMENTAL EYE RESEARCH (2021)
AlphaFold heralds a data-driven revolution in biology and medicine
Janet M. Thornton et al.
NATURE MEDICINE (2021)
Could AlphaFold revolutionize chemical therapeutics?
Alexander B. Tong et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2021)
Highly accurate protein structure prediction with AlphaFold
John Jumper et al.
NATURE (2021)
Hotspots of Human Mutation
Alex V. Nesta et al.
TRENDS IN GENETICS (2021)
A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression
Jing Liu et al.
NATURE COMMUNICATIONS (2021)
Lineage Plasticity in Cancer: The Tale of a Skin-Walker
Archana P. Thankamony et al.
CANCERS (2021)
Targeting RB1 Loss in Cancers
Paing Linn et al.
CANCERS (2021)
Xanthatin Selectively Targets Retinoblastoma by Inhibiting the PLK1-Mediated Cell Cycle
Jie Yang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2021)
Significance of BRCA2 and RB1 Co-loss in Aggressive Prostate Cancer Progression
Goutam Chakraborty et al.
CLINICAL CANCER RESEARCH (2020)
Improved protein structure prediction using potentials from deep learning
Andrew W. Senior et al.
NATURE (2020)
The repertoire of mutational signatures in human cancer
Ludmil B. Alexandrov et al.
NATURE (2020)
Tumor Milieu Controlled by RB Tumor Suppressor
Shunsuke Kitajima et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Spectrum of RB1 Germline Mutations and Clinical Features in Unrelated Chinese Patients With Retinoblastoma
Xiaoping Lan et al.
FRONTIERS IN GENETICS (2020)
Role of RB1 in human embryonic stem cell-derived retinal organoids
Canbin Zheng et al.
DEVELOPMENTAL BIOLOGY (2020)
Association Between Genotype and Phenotype in Consecutive Unrelated Individuals With Retinoblastoma
Flore Salviat et al.
JAMA OPHTHALMOLOGY (2020)
DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons
Therese Wilhelm et al.
GENES (2020)
A Multicenter, International Collaborative Study for American Joint Committee on Cancer Staging of Retinoblastoma Part II: Treatment Success and Globe Salvage
Ankit Singh Tomar et al.
OPHTHALMOLOGY (2020)
A Multicenter, International Collaborative Study for American Joint Committee on Cancer Staging of Retinoblastoma Part I: Metastasis-Associated Mortality
Ankit Singh Tomar et al.
OPHTHALMOLOGY (2020)
Roles of plant retinoblastoma protein: cell cycle and beyond
Benedicte Desvoyes et al.
EMBO JOURNAL (2020)
Metabolism
Ayesha Judge et al.
UNDERSTANDING BIOCHEMISTRY 6 (2020)
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics
Junfang Lyu et al.
NATURE COMMUNICATIONS (2020)
Human embryonic stem cell-derived organoid retinoblastoma reveals a cancerous origin
Hui Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Impact of Lineage Plasticity to and from a Neuroendocrine Phenotype on Progression and Response in Prostate and Lung Cancers
Mark A. Rubin et al.
MOLECULAR CELL (2020)
Tumor Suppressors RB1 and CDKN2a Cooperatively Regulate Cell-Cycle Progression and Differentiation During Cardiomyocyte Development and Repair Implications for Stimulating Neomyogenesis With Cell-Based Therapy
Konstantinos E. Hatzistergos et al.
CIRCULATION RESEARCH (2019)
Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01
Guillem Pascual-Pasto et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Drugging RB1 Deficiency: Synthetic Lethality with Aurora Kinases
Frederick A. Dick et al.
CANCER DISCOVERY (2019)
RB1 Deletion in Retinoblastoma Protein Pathway-Disrupted Cells Results in DNA Damage and Cancer Progression
Aren E. Marshall et al.
MOLECULAR AND CELLULAR BIOLOGY (2019)
RB constrains lineage fidelity and multiple stages of tumour progression and metastasis
David M. Walter et al.
NATURE (2019)
Mechanisms of Genomic Instability in Breast Cancer
Pascal H. G. Duijf et al.
TRENDS IN MOLECULAR MEDICINE (2019)
Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion
Fengkai Li et al.
CANCER RESEARCH (2019)
Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes
Michael Offin et al.
JOURNAL OF THORACIC ONCOLOGY (2019)
Diminished Condensin Gene Expression Drives Chromosome Instability That May Contribute to Colorectal Cancer Pathogenesis
Allison K. Baergen et al.
CANCERS (2019)
The RB1 Story: Characterization and Cloning of the First Tumor Suppressor Gene
Jesse L. Berry et al.
GENES (2019)
Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene
Xueqian Gong et al.
CANCER DISCOVERY (2019)
Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival
Matthew G. Oser et al.
CANCER DISCOVERY (2019)
Cell Cycle and Beyond: Exploiting New RB1 Controlled Mechanisms for Cancer Therapy
Erik S. Knudsen et al.
TRENDS IN CANCER (2019)
Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma
Ran Wei et al.
JCI INSIGHT (2019)
A laser-activated multifunctional targeted nanoagent for imaging and gene therapy in a mouse xenograft model with retinoblastoma Y79 cells
Mingxing Wu et al.
ACTA BIOMATERIALIA (2018)
Evaluating tumor-suppressor gene combinations
James Kim et al.
NATURE GENETICS (2018)
Rb is required for retinal angiogenesis and lamination
Yi Zhou et al.
CELL DEATH & DISEASE (2018)
Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer
Agnieszka K. Witkiewicz et al.
CELL REPORTS (2018)
High speed of fork progression induces DNA replication stress and genomic instability
Apolinar Maya-Mendoza et al.
NATURE (2018)
The Next Phase of Human Gene-Therapy Oversight
Francis S. Collins et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Germline mutation contribution to chromosomal instability
Sock Hoai Chan et al.
ENDOCRINE-RELATED CANCER (2017)
The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity
S. Kitajima et al.
ONCOGENE (2017)
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53-and RB1-deficient prostate cancer
Ping Mu et al.
SCIENCE (2017)
Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance
Sheng Yu Ku et al.
SCIENCE (2017)
The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression
I. Gonzalez-Vasconcellos et al.
SCIENTIFIC REPORTS (2017)
Mitochondrial OXPHOS Induced by RB1 Deficiency in Breast Cancer: Implications for Anabolic Metabolism, Stemness, and Metastasis
Eldad Zacksenhaus et al.
TRENDS IN CANCER (2017)
Microenvironmental regulation of tumour angiogenesis
Michele de Palma et al.
NATURE REVIEWS CANCER (2017)
De novo mutational profile in RB1 clarified using a mutation rate modeling algorithm
Varun Aggarwala et al.
BMC GENOMICS (2017)
The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more personalized approach to cancer staging
Mahul B. Amin et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2017)
Hallmarks of cancer stem cell metabolism
Patricia Sancho et al.
BRITISH JOURNAL OF CANCER (2016)
CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells
Alan L. Chang et al.
CANCER RESEARCH (2016)
Genotype-phenotype correlation in the presentation of retinoblastoma among 149 patients
Shahar Frenkel et al.
EXPERIMENTAL EYE RESEARCH (2016)
RB1: a prototype tumor suppressor and an enigma
Nicholas J. Dyson
GENES & DEVELOPMENT (2016)
RB1 deficiency in triple-negative breast cancer induces rnitochondrial protein translation
Robert A. Jones et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Emerging Links between E2F Control and Mitochondrial Function
Elizaveta V. Benevolenskaya et al.
CANCER RESEARCH (2015)
Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis
Michael S. Kareta et al.
CELL STEM CELL (2015)
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
Matthew J. Niederst et al.
NATURE COMMUNICATIONS (2015)
RB1 dual role in proliferation and apoptosis: Cell fate control and implications for cancer therapy
Paola Indovina et al.
ONCOTARGET (2015)
PRMT4-Mediated Arginine Methylation Negatively Regulates Retinoblastoma Tumor Suppressor Protein and Promotes E2F-1 Dissociation
Kevin Y. Kim et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
Phosphorylation of the Retinoblastoma protein (Rb) on serine-807 is required for association with Bax
Lisa A. Antonucci et al.
CELL CYCLE (2014)
The survival gene MED4 explains low penetrance retinoblastoma in patients with large RB1 deletion
Catherine Dehainault et al.
HUMAN MOLECULAR GENETICS (2014)
Suppression of Genome Instability in pRB-Deficient Cells by Enhancement of Chromosome Cohesion
Amity L. Manning et al.
MOLECULAR CELL (2014)
Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation
A. L. Manning et al.
ONCOGENE (2014)
Control of glutamine metabolism by the tumor suppressor Rb
M. R. Reynolds et al.
ONCOGENE (2014)
Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor
Simon M. Carr et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Cyclin D activates the Rb tumor suppressor by mono-phosphorylation
Anil M. Narasimha et al.
ELIFE (2014)
Rb1 Haploinsufficiency Promotes Telomere Attrition and Radiation-Induced Genomic Instability
Iria Gonzalez-Vasconcellos et al.
CANCER RESEARCH (2013)
Fine mapping of whole RB1 gene deletions in retinoblastoma patients confirms PCDH8 as a candidate gene for psychomotor delay
Laurent Castera et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2013)
The retinoblastoma protein induces apoptosis directly at the mitochondria
Keren I. Hilgendorf et al.
GENES & DEVELOPMENT (2013)
Loss of RBF1 changes glutamine catabolism
Brandon N. Nicolay et al.
GENES & DEVELOPMENT (2013)
Combination of oncolytic adenovirus and endostatin inhibits human retinoblastoma in an in vivo mouse model
Huiping Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2013)
Folding of a Cyclin Box LINKING MULTITARGET BINDING TO MARGINAL STABILITY, OLIGOMERIZATION, AND AGGREGATION OF THE RETINOBLASTOMA TUMOR SUPPRESSOR AB POCKET DOMAIN
Lucia B. Chemes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
On the role of retinoblastoma family proteins in the establishment and maintenance of the epigenetic landscape
Francesco Paolo Fiorentino et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2013)
RB1 in cancer: Different mechanisms of RB1 inactivation and alterations of pRb pathway in tumorigenesis
Riccardo Di Fiore et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2013)
Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation
Maya Kansara et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Replication stress links structural and numerical cancer chromosomal instability
Rebecca A. Burrell et al.
NATURE (2013)
Molecular mechanisms underlying RB protein function
Frederick A. Dick et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Deciphering the retinoblastoma protein phosphorylation code
Seth M. Rubin
TRENDS IN BIOCHEMICAL SCIENCES (2013)
Rb1 family mutation is sufficient for sarcoma initiation
Yongqing Liu et al.
NATURE COMMUNICATIONS (2013)
RB-Pathway Disruption Is Associated with Improved Response to Neoadjuvant Chemotherapy in Breast Cancer
Agnieszka K. Witkiewicz et al.
CLINICAL CANCER RESEARCH (2012)
The retinoblastoma tumor suppressor and stem cell biology
Julien Sage
GENES & DEVELOPMENT (2012)
Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control
Jason R. Burke et al.
GENES & DEVELOPMENT (2012)
Combined Treatment with an Oncolytic Adenovirus and Antitumor Activity of Vincristine against Retinoblastoma Cells
Xin Song et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)
Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation
M. Sangwan et al.
ONCOGENE (2012)
ErbB receptor tyrosine kinase/NF-κB signaling controls mammosphere formation in human breast cancer
Kunihiko Hinohara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle
Shauna A. Henley et al.
CELL DIVISION (2012)
GENOMIC INSTABILITY IN CANCER - OPINION RB: mitotic implications of a tumour suppressor
Amity L. Manning et al.
NATURE REVIEWS CANCER (2012)
Low penetrance of retinoblastoma for p.V654L mutation of the RB1 gene
Chia-Cheng Hung et al.
BMC MEDICAL GENETICS (2011)
Mad2 Is a Critical Mediator of the Chromosome Instability Observed upon Rb and p53 Pathway Inhibition
Juan-Manuel Schvartzman et al.
CANCER CELL (2011)
Multiple pathways counteract cell death induced by RB1 loss Implications for cancer
Giovanni Ciavarra et al.
CELL CYCLE (2011)
Drosophila Stem Cell Niches: A Decade of Discovery Suggests a Unified View of Stem Cell Regulation
Vicki P. Losick et al.
DEVELOPMENTAL CELL (2011)
Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein
Simon M. Carr et al.
EMBO JOURNAL (2011)
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
Bin-Zhi Qian et al.
NATURE (2011)
E2F transcription factor-1 regulates oxidative metabolism
Emilie Blanchet et al.
NATURE CELL BIOLOGY (2011)
RB-pathway disruption in breast cancer Differential association with disease subtypes, disease-specific prognosis and therapeutic response
Adam Ertel et al.
CELL CYCLE (2010)
Transient Inactivation of Rb and ARF Yields Regenerative Cells from Postmitotic Mammalian Muscle
Kostandin V. Pajcini et al.
CELL STEM CELL (2010)
Chromosomal anomalies in patients with retinoblastoma
Miriam G. Wilson et al.
CLINICAL GENETICS (2010)
Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive
Courtney H. Coschi et al.
GENES & DEVELOPMENT (2010)
Loss of pRB causes centromere dysfunction and chromosomal instability
Amity L. Manning et al.
GENES & DEVELOPMENT (2010)
Rescue of myogenic defects in Rb-deficient cells by inhibition of autophagy or by hypoxia-induced glycolytic shift
Giovanni Ciavarra et al.
JOURNAL OF CELL BIOLOGY (2010)
Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status
Zhe Jiang et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
Ankur Sharma et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers
Elisabet Ognedal Berge et al.
MOLECULAR CANCER (2010)
Signatures of mutation and selection in the cancer genome
Graham R. Bignell et al.
NATURE (2010)
Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1(+/-) mice
Hongbo Wang et al.
NATURE GENETICS (2010)
RNAi mediated acute depletion of Retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation
Angela Amato et al.
BMC CELL BIOLOGY (2009)
MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
Chi V. Dang et al.
CLINICAL CANCER RESEARCH (2009)
A comprehensive, sensitive and economical approach for the detection of mutations in the RB1 gene in retinoblastoma
Vidya Latha Parsam et al.
JOURNAL OF GENETICS (2009)
AAV-mediated Local Delivery of Interferon-beta for the Treatment of Retinoblastoma in Preclinical Models
Chie-Schin Shih et al.
NEUROMOLECULAR MEDICINE (2009)
p53 and E2f: partners in life and death
Shirley Polager et al.
NATURE REVIEWS CANCER (2009)
Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition
Yoshimi Arima et al.
CANCER RESEARCH (2008)
Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis
Vijay G. Sankaran et al.
GENES & DEVELOPMENT (2008)
RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3
Michelle S. Longworth et al.
GENES & DEVELOPMENT (2008)
Statement on guidance for genetic counseling in advanced paternal age
Helga V. Toriello et al.
GENETICS IN MEDICINE (2008)
Regulation of the PDK4 isozyme by the Rb-E2F1 complex
Michael C. F. Hsieh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
Pasquale Sansone et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure
Nassim Dali-Youcef et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Loss of RB compromises specific heterochromatin modifications and modulates HP1α dynamics
Hasan Siddiqui et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit
Ulrich K. Binne et al.
NATURE CELL BIOLOGY (2007)
The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer
Emily E. Bosco et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Rb is critical in a mammalian tissue stem cell population
Pamela L. Wenzel et al.
GENES & DEVELOPMENT (2007)
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
Rocio Sotillo et al.
CANCER CELL (2007)
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
Flora Iovino et al.
MOLECULAR CANCER (2006)
The retinoblastoma protein regulates pericentric heterochromatin
CE Isaac et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
RBI gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database -: art. no. 53
JR Valverde et al.
BMC GENETICS (2005)
Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir
P Chévez-Barrios et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Retinoblastoma in the 20th century: Past success and future challenges - The Weisenfeld lecture
DH Abramson
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Sensitive multistep clinical molecular screening of 180 unrelated individuals with retinoblastoma detects 36 novel mutations in the RB1 gene
KE Nichols et al.
HUMAN MUTATION (2005)
The search for the retinoblastoma cell of origin
MA Dyer et al.
NATURE REVIEWS CANCER (2005)
Differential regulation of apoptotic genes by Rb in human versus mouse cells
AP Young et al.
ONCOGENE (2004)
Acetylation regulates the differentiation-specific functions of the retinoblastoma protein
DX Nguyen et al.
EMBO JOURNAL (2004)
Retinoblastoma: Revisiting the model prototype of inherited cancer
DR Lohmann et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2004)
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
E Hernando et al.
NATURE (2004)
Evaluation of MYC E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays
JW Kim et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant
P Ji et al.
MOLECULAR CELL (2004)
E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas
U Ziebold et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase
J Wells et al.
ONCOGENE (2003)
Role of the retinoblastoma protein in differentiation and senescence
DM Thomas et al.
CANCER BIOLOGY & THERAPY (2003)
Extra-embryonic function of Rb is essential for embryonic development and viability
LZ Wu et al.
NATURE (2003)
Sensitive and efficient detection of RB1 gene mutations enhances care for families with retinoblastoma
S Richter et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
A role for the Rb family of proteins in controlling telomere length
M García-Cao et al.
NATURE GENETICS (2002)
Accelerated publication -: Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
RC Osthus et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)